Precision medicine approaches for heterogeneous conditions such as autism spectrum disorders (The need for a biomarker exploration phase in clinical trials - Phase 2m)

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EDITORIAL

Published on 19 Jan 2023

Editorial: Precision medicine approaches for heterogeneous conditions such as autism spectrum disorders (The need for a biomarker exploration phase in clinical trials - Phase 2m)

David Q. Beversdorf
Evdokia Anagnostou
Antonio Hardan
Paul Wang
Craig A. Erickson
Thomas W. Frazier
Jeremy Veenstra-VanderWeele

doi 10.3389/fpsyt.2022.1079006

2,147 views
5 citations

BRIEF RESEARCH REPORT

Published on 22 Jul 2022

Relationship Between MR Spectroscopy-Detected Glutamatergic Neurometabolites and Changes in Social Behaviors in a Pilot Open-Label Trial of Memantine for Adults With Autism Spectrum Disorder

Neetu Nair
John Patrick Hegarty
Carmen Mihaela Cirstea
Meng Gu
Carrina Brooke Appling
David Quentin Beversdorf

doi 10.3389/fpsyt.2022.898006

1,260 views

ORIGINAL RESEARCH

Published on 22 Jun 2022

Distinct Patterns of Cognitive Outcome in Young Children With Autism Spectrum Disorder Receiving the Early Start Denver Model

Michel Godel
François Robain
Nada Kojovic
Martina Franchini
Hilary Wood de Wilde
Marie Schaer

doi 10.3389/fpsyt.2022.835580

2,897 views
8 citations

ORIGINAL RESEARCH

Published on 09 May 2022

Identifying Age Based Maturation in the ERP Response to Faces in Children With Autism: Implications for Developing Biomarkers for Use in Clinical Trials

Sara Jane Webb
Iris Emerman
Catherine Sugar
Damla Senturk
Adam J. Naples
Susan Faja
Jessica Benton
Heather Borland
Carter Carlos
13 more
the Autism Biomarkers Consortium for Clinical Trials

doi 10.3389/fpsyt.2022.841236

2,289 views
6 citations

ORIGINAL RESEARCH

Published on 14 Apr 2022

Motor Cortex Excitation/Inhibition Imbalance in Young Adults With Autism Spectrum Disorder: A MRS-TMS Approach

Inês Bernardino
Ana Dionísio
Inês R. Violante
Raquel Monteiro
Miguel Castelo-Branco

doi 10.3389/fpsyt.2022.860448

3,147 views
14 citations

ORIGINAL RESEARCH

Published on 08 Mar 2022

Regressive Autism Spectrum Disorder: High Levels of Total Secreted Amyloid Precursor Protein and Secreted Amyloid Precursor Protein-α in Plasma

Xiaoli Li
Ping Zhou
Qiu Li
Bin Peng
Yupeng Cun
Ying Dai
Hua Wei
Xiao Liu
Yang Yu
7 more
Li Chen

doi 10.3389/fpsyt.2022.809543

5,067 views
5 citations

PERSPECTIVE

Published on 25 Feb 2022

Rethinking Autism Intervention Science: A Dynamic Perspective

Yun-Ju Chen
Eric Duku
Stelios Georgiades

doi 10.3389/fpsyt.2022.827406

3,280 views
5 citations

SYSTEMATIC REVIEW

Published on 27 Jan 2022

Examining Effectiveness and Predictors of Treatment Response of Pivotal Response Treatment in Autism: An Umbrella Review and a Meta-Analysis

Mirko Uljarević
Wesley Billingham
Matthew N. Cooper
Patrick Condron
Antonio Y. Hardan

doi 10.3389/fpsyt.2021.766150

7,455 views
11 citations

ORIGINAL RESEARCH

Published on 20 Jan 2022

Saliva RNA Biomarkers of Gastrointestinal Dysfunction in Children With Autism and Neurodevelopmental Disorders: Potential Implications for Precision Medicine

David Q. Beversdorf
Kristin Sohl
David Levitskiy
Priscilla Tennant
Robin P. Goin-Kochel
Rebecca C. Shaffer
Alexandra Confair
Frank A. Middleton
Steven D. Hicks

doi 10.3389/fpsyt.2021.824933

4,776 views
6 citations

ORIGINAL RESEARCH

Published on 03 Nov 2021

Investigating Changes in Reward-Related Neural Correlates After PEERS Intervention in Adolescents With ASD: Preliminary Evidence of a “Precision Medicine” Approach

Elizabeth Baker
Elina Veytsman
Tricia Choy
Jan Blacher
Katherine K. M. Stavropoulos

doi 10.3389/fpsyt.2021.742280

2,630 views
6 citations

STUDY PROTOCOL

Published on 24 Aug 2021

A Phase II Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy, Safety, and Tolerability of Arbaclofen Administered for the Treatment of Social Function in Children and Adolescents With Autism Spectrum Disorders: Study Protocol for AIMS-2-TRIALS-CT1

Mara Parellada
Antonia San José Cáceres
Melanie Palmer
Richard Delorme
Emily J. H. Jones
Jeremy R. Parr
Evdokia Anagnostou
Declan G. M. Murphy
Eva Loth
3 more
Celso Arango

doi 10.3389/fpsyt.2021.701729

6,793 views
14 citations

BRIEF RESEARCH REPORT

Published on 29 Jun 2021

Brief Report: Preliminary Evidence of the N170 as a Biomarker of Response to Treatment in Autism Spectrum Disorder

Shashwat Kala
Max J. Rolison
Dominic A. Trevisan
Adam J. Naples
Kevin Pelphrey
Pamela Ventola
James C. McPartland

doi 10.3389/fpsyt.2021.709382

3,718 views
9 citations

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Articles

Editorial: Precision medicine approaches for heterogeneous conditions such as autism spectrum disorders (The need for a biomarker exploration phase in clinical trials - Phase 2m)

Relationship Between MR Spectroscopy-Detected Glutamatergic Neurometabolites and Changes in Social Behaviors in a Pilot Open-Label Trial of Memantine for Adults With Autism Spectrum Disorder

Distinct Patterns of Cognitive Outcome in Young Children With Autism Spectrum Disorder Receiving the Early Start Denver Model

Identifying Age Based Maturation in the ERP Response to Faces in Children With Autism: Implications for Developing Biomarkers for Use in Clinical Trials

Motor Cortex Excitation/Inhibition Imbalance in Young Adults With Autism Spectrum Disorder: A MRS-TMS Approach

Regressive Autism Spectrum Disorder: High Levels of Total Secreted Amyloid Precursor Protein and Secreted Amyloid Precursor Protein-α in Plasma

Rethinking Autism Intervention Science: A Dynamic Perspective

Examining Effectiveness and Predictors of Treatment Response of Pivotal Response Treatment in Autism: An Umbrella Review and a Meta-Analysis

Saliva RNA Biomarkers of Gastrointestinal Dysfunction in Children With Autism and Neurodevelopmental Disorders: Potential Implications for Precision Medicine

Investigating Changes in Reward-Related Neural Correlates After PEERS Intervention in Adolescents With ASD: Preliminary Evidence of a “Precision Medicine” Approach

A Phase II Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy, Safety, and Tolerability of Arbaclofen Administered for the Treatment of Social Function in Children and Adolescents With Autism Spectrum Disorders: Study Protocol for AIMS-2-TRIALS-CT1

Brief Report: Preliminary Evidence of the N170 as a Biomarker of Response to Treatment in Autism Spectrum Disorder

Frontiers in Psychiatry

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