About this Research Topic
Autophagy is a self-eating cellular catabolic pathway, through which long-lived proteins, damaged organelles and misfolded proteins are degraded and recycled for the maintenance of cellular homeostasis and normal cellular functions. Autophagy plays an important homeostatic role in the regulation of various cell activities and signalling. In recent years, the role of autophagy in the pathogenesis and progression of various inflammation-related diseases has been widely reported, showing the potential importance of autophagy in the regulation of such disorders.
Here, we aim to collect and assess the world's latest studies on uncovering the role of autophagy in inflammation-related diseases through starting a Frontiers Research Topic, aiming to draw a clearer picture for researchers on this issue. We believe that this Research Topic would provide a novel insight in taking advantage of autophagy in the treatment of inflammation-related diseases.
In this Research Topic, we would like to collect manuscripts that address the role of autophagy in inflammation-related disorders including inflammatory bowel disease, multiple sclerosis, atherosclerosis, ischemia. Those which exploring the underlying mechanisms related to autophagy would be preferred in the collection. In addition, all forms of autophagy besides macroautophagy would be encouraged in discussion in inflammation-related diseases. In this Research Topic, original articles, reviews, mini-reviews and meta-analysis are welcomed in submission. Researchers from all countries would be very much welcomed in submitting their brilliant works which are themed around the study of autophagy in inflammation-related diseases.
Keywords: autophagy, inflammation, inflammasome, apoptosis, macrophage
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.