Novel Insights into Obesity-Related Diseases

Obesity is a complex disease with an excessive amount of ectopically distributed body fat, which leads to not only an unfavourable cosmetic concern but also an increased risk of type 2 diabetes, sleep apnea syndrome, polycystic ovary syndrome, cardiovascular diseases, etc., which are known as obesity-related diseases. Both obesity and related diseases have reached epidemic proportions globally, being a major health and social problem worldwide. As a result, a comprehensive understanding of the pathogenesis, along with the attempt to prevent or treat obesity as well as the related diseases are of great importance.

Obesity results from a combination of genetic factors, sedentary lifestyle, environmental influences, and personal preference for diet. Traditional interventions do not achieve ideal outcomes. In recent years, the most effective and promising treatment for obesity and related diseases is bariatric surgery, which leads to rapid and sustained weight loss and amelioration of obesity and related diseases. Nevertheless, the underlying physiological mechanisms remain unclear. A comprehensive understanding of bariatric surgery will help select obese patients who benefit the most and may provide a potential target for drugs. In this research topic, we encourage submissions on the latest advances in the pathogenesis of obesity, mechanisms of bariatric surgery and other novel concepts related to obesity prevention and treatment.

We encourage contributions to this topic exploring:

-pathogenesis of obesity and related diseases

-metabolic disorders in obesity and related diseases

-mechanisms of bariatric surgery in ameliorating obesity and related diseases

-other novel concepts related to obesity prevention and treatment

Article types accepted include original research, review, and systematic review.