Stress-related Diseases and Dysfunctions

Inadequate responses to environmental challenges are known to be a risk factor in the development of dysfunctions and diseases. However, the mechanistic features underlying different pathophysiological processes triggered from stressful situations are poorly understood. Global epidemiological data show that the current knowledge on the mechanisms involved in the stress-related diseases, and therapeutic arsenal against these diseases need to be broadened, in order to pave ways for novel and efficient therapeutic approaches interfering directly with the morbidity and mortality.

The aim of this Research Topic, as Integrative Physiology, is to collect high quality science that unravels details on the mechanisms involved in the dysfunctions and diseases related to acute and chronic stress exposure, in different experimental models.

This Research Topic welcomes manuscripts resulting from cutting-edge research that approach neurobiological, autonomic, metabolic, hemodynamic, endocrine, behavioral and pharmacological aspects involved in the pathophysiology and treatments of dysfunctions and diseases found in different models of acute and chronic stress exposure.