About this Research Topic
Cancer is one of the leading causes of mortality worldwide. The association between physical exercise and many aspects of cancer such as incidence and prognosis has been well documented. In addition, many risk factors of cancer including obesity, aging, and inflammation are found to be affected by physical exercise. However, little is known about the molecular mechanisms underlying their connections. Due to the rapid development of multi-omics technologies and their reduced cost, new discoveries of the molecular foundations of physical exercise and their potential links with cancer are being illuminated.
Although it is widely recognized that physical exercise has a positive effect on cancer in terms of morbidity, prognosis, rehabilitation, and even therapy, there are issues in this field awaiting a deeper understanding. For example, are specific forms of exercise beneficial to alleviate certain cancer symptoms, or indicate a better prognosis of certain cancer types at the molecular level? Additionally, what is understood of the key signaling pathways in cancer cells in response to physical exercise? In this research topic, we aim to summarize the recent signs of progress in this field, discuss their potential impact on clinical practice and try to project future research directions.
The manuscripts submitted to this research topic can be either review or research articles. Themes to be covered in this research topic may include, but are not limited to:
• Molecular mechanisms underlying exercise and cancer treatment
• Molecular mechanism underlying exercise and cancer morbidity
• Molecular mechanism underlying exercise and cancer rehabilitation
• Multi-omics technologies for investigating the molecular foundation of exercise and cancer
• Molecular Immunology related to exercise and cancer
• Redox homeostasis related to exercise and cancer
Keywords: Cancer, Exercise, Multi-Omics, Inflammation, Homeostasis, Clinical, Obesity, Aging
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
