About this Research Topic
Similarly, multiple studies investigating pacing techniques for controlling the heart in real-time and preventing the onset of life-threatening arrhythmias have focused on the prediction and control of cardiac alternans, a suggested precursor to fatal tachy-arrhythmias. However, given the spatiotemporal and structural complexity of the human heart, designing algorithms to effectively suppress alternans and prevent fatal cardiac rhythms has been challenging, especially in chronic disease and ambulatory models. Hence, there is an unmet clinical need to decipher electrical intervention and autonomic modulation techniques to inhibit or control the onset of abnormal cardiac rhythms.
The goal of this Research Topic is to cover novel treatment strategies for the prediction, prevention and control of arrhythmias, based on cardiac pacemaking and neuromodulation techniques. We invite articles describing the recent advances in cardio-neurology by providing insights into approaches for controlling abnormal cardiac rhythms using electrical interventions.
We welcome original research, brief reports or review articles on the following themes:
1) pacing strategies for prevention or control of cardiac alternans and arrhythmias
2) application of neuromodulation techniques like vagal stimulation for control of cardiac arrhythmias
3) novel pacemaker strategies in healthy or diseased, in-silico, animal or clinical models
4) mechanistic insights into effect of parasympathetic or sympathetic activation on cardiac electrophysiology
5) techniques for cardiac pacing or neuromodulation in ambulatory models
Keywords: cardiac pacing, alternans, arrhythmias, neuromodulation, vagal stimulation
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