Anatomical Substrate of Neural Circuit Physiology

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About this Research Topic

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Background

Cell-type specific circuits impose biological limits in the phase-space of physiological phenomena. Distinct invertebrate and vertebrate nervous systems exhibit systems physiological events, including central pattern generators, punctate events such as hippocampal sharp waves, as well as widespread global events in the mammalian brain (eg, sleep spindles) that are bound by underlying neuroanatomical connectivity. The current topic focuses on the underlying anatomical substrate.
Neurophysiological phenomenon involving the interactions (social dynamics) between neurons, involves both cell-specific physiology and anatomical connectivity, among a diverse group of neurons with both specific physiological/anatomical boundaries. Rhythms in the brain (eg, delta, alpha, beta, theta and gamma), as well as more punctate events (eg, hippocampal sharp wave) are constrained by anatomical features of individual cells and their connectivity. In contrast to a focus on the "function" of such events, the current topic seeks to advance an understanding that such events are bound by cell morphology and micro-macro neuroanatomy.The current topic is focused on how neuroanatomy imposes boundaries on distinct physiological events and oscillatory rhythms. We wish to focus on how cell-type specific circuits, micro-circuitry and long-range feedback/feedforward/loop anatomy support and bound punctate physiological events (eg, sharp waves), and oscillatory rhythms (eg., sleep spindles, theta, alpha, beta, gamma oscillations). 
This topic seeks Original Research, Systemic Review, Methods, Review, Mini-Review, Hypothesis and Theory, Perspective, Data Report, Brief Research Reports and General Commentary submissions that relate to how neuroanatomy bounds/supports/constrains focal or long-range neurophysiological phenomena, including dissenting views that might suggest that the underlying neuroanatomy does not constrain/bound functionality.

Keywords: neuroanatomy, neurophysiology, oscillations, circuits, cell-type

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