About this Research Topic
According to the World Health Organization, one in 10 people live in places where the air quality is unsafe for their health and approximately 7 millions people worldwide die every year from exposure to polluted air. With the worsening of both indoor and outdoor air quality, there is a growing risk of mortality linked to a combination of respiratory and cardiovascular complications such as stroke, lung cancer, ischemic heart disease, acute lower respiratory infection and chronic obstructive pulmonary disease. Besides an increased environmental risk of early death, pollution impacts also human health, leading to the development and exacerbation of many chronic and debilitating conditions in multiple organ systems. In fact, pollutants can not only penetrate our respiratory and circulatory systems, but can also affect skin, eyes and even brain. Adverse health effects deriving from pollution are influenced by a variety of factors including the type of pollutant and its concentration, but also by the length of exposure and pre-existing health status.
The need to address the impact of environmental pollution on human health has never been clearer as highlighted by a growing number of air-pollution-related illnesses and deaths. To identify the most appropriate approaches to preventing and/or modulating the effects of pollution toxicity on humans, it’s important to improve the understanding of the specific biological and biochemical mechanisms by which harmful atmospheric pollutants affect disease risk. In a future scenario of increasing health and environmental concerns, one of the most fascinating and currently interesting challenges faced by scientists is to unravel the complex interaction between pollutants acting simultaneously with heterogeneous mechanisms of action and the complicated nature of human tissues that can respond differently to the same dangerous agent.
The current Research Topic encourages the submission of different kind of manuscripts - Original Research papers, Reviews, Mini-Reviews, Commentaries, Hypothesis and Theory papers, Opinion manuscripts that will include recent and state-of-art progress and achievements on the links between health conditions and pollution toxicity at a molecular and cellular level.
Areas to be covered in this Research Topic may include, but are not limited to:
• Understanding impacts of pollution toxicity on specific organ conditions i.e. skin, lungs, heart, etc
• Improving understanding of the connections between pollution and impaired neurodevelopment and cognitive ability
• Biomarkers
• Biomonitoring and adverse/toxic health effects
• Air, soil, water and biota chemical pollutants and health
• Microplastics
• Chemical stressors
• Ecotoxicology
• Environmental epidemiology
• Environmental toxicology
• Environmental Epigenetics
• Environment-related "omics"
• Indoor and outdoor air pollution
• Risks and public health
• Metals and health
• Mechanisms of toxicity
• Pollution and oxidative damage
• Pollution and inflammation
• Exposome and premature aging
The need to address the impact of environmental pollution on human health has never been clearer as highlighted by a growing number of air-pollution-related illnesses and deaths. To identify the most appropriate approaches to preventing and/or modulating the effects of pollution toxicity on humans, it’s important to improve the understanding of the specific biological and biochemical mechanisms by which harmful atmospheric pollutants affect disease risk. In a future scenario of increasing health and environmental concerns, one of the most fascinating and currently interesting challenges faced by scientists is to unravel the complex interaction between pollutants acting simultaneously with heterogeneous mechanisms of action and the complicated nature of human tissues that can respond differently to the same dangerous agent.
The current Research Topic encourages the submission of different kind of manuscripts - Original Research papers, Reviews, Mini-Reviews, Commentaries, Hypothesis and Theory papers, Opinion manuscripts that will include recent and state-of-art progress and achievements on the links between health conditions and pollution toxicity at a molecular and cellular level.
Areas to be covered in this Research Topic may include, but are not limited to:
• Understanding impacts of pollution toxicity on specific organ conditions i.e. skin, lungs, heart, etc
• Improving understanding of the connections between pollution and impaired neurodevelopment and cognitive ability
• Biomarkers
• Biomonitoring and adverse/toxic health effects
• Air, soil, water and biota chemical pollutants and health
• Microplastics
• Chemical stressors
• Ecotoxicology
• Environmental epidemiology
• Environmental toxicology
• Environmental Epigenetics
• Environment-related "omics"
• Indoor and outdoor air pollution
• Risks and public health
• Metals and health
• Mechanisms of toxicity
• Pollution and oxidative damage
• Pollution and inflammation
• Exposome and premature aging
Keywords: Pollutants, antioxidant response, oxinflammation, inflammaging, neuroinflammation
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
