Trabectedin, Lurbinectedin, and Other Marine-Derived Anticancer Alkaloids on Solid Cancer: Mechanisms of Action, Clinical Impact, and Future Perspectives

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EDITORIAL

Published on 25 Jan 2023

Editorial: Trabectedin, lurbinectedin, and other marine-derived anticancer alkaloids on solid cancer: Mechanisms of action, clinical impact, and future perspectives

Alberto Zambelli
Maurizio D’Incalci

doi 10.3389/fonc.2022.1115342

1,146 views
1 citation

SYSTEMATIC REVIEW

Published on 03 Nov 2022

Trabectedin and lurbinectedin: Mechanisms of action, clinical impact, and future perspectives in uterine and soft tissue sarcoma, ovarian carcinoma, and endometrial carcinoma

Angiolo Gadducci
Stefania Cosio

doi 10.3389/fonc.2022.914342

4,535 views
14 citations

REVIEW

Published on 08 Sep 2022

From seaside to bedside: Current evidence and future perspectives in the treatment of breast cancer using marine compounds

Rita De Sanctis
Flavia Jacobs
Chiara Benvenuti
Mariangela Gaudio
Raul Franceschini
Richard Tancredi
Paolo Pedrazzoli
Armando Santoro
Alberto Zambelli

doi 10.3389/fphar.2022.909566

3,361 views
9 citations

ORIGINAL RESEARCH

Published on 30 Aug 2022

DNA damage response and repair genes in advanced bone and soft tissue sarcomas: An 8-gene signature as a candidate predictive biomarker of response to trabectedin and olaparib combination

Alessandra Merlini
Maria Laura Centomo
Giulio Ferrero
Giulia Chiabotto
Umberto Miglio
Enrico Berrino
Giorgia Giordano
Silvia Brusco
Alberto Pisacane
13 more
Giovanni Grignani

doi 10.3389/fonc.2022.844250

2,635 views
7 citations

ORIGINAL RESEARCH

Published on 03 Jun 2022

Determination of Extravasation Effects of Nal-Iri and Trabectedin and Evaluation of Treatment Options for Trabectedin Extravasation in a Preclinical Animal Model

Omar Keritam
Viktoria Juhasz
Christian Schöfer
Christiane Thallinger
Marie-Bernadette Aretin
Gernot Schabbauer
Johannes Breuss
Matthias Unseld
Pavel Uhrin

doi 10.3389/fphar.2022.875695

2,153 views
4 citations

REVIEW

Published on 30 Mar 2022

Efficacy of Eribulin in Soft Tissue Sarcomas

Edward Phillips
Robin L. Jones
Paul Huang
Antonia Digklia

doi 10.3389/fphar.2022.869754

7,362 views
19 citations

ORIGINAL RESEARCH

Published on 17 Mar 2022

Antitumoral Effect of Plocabulin in High Grade Serous Ovarian Carcinoma Cell Line Models

Victoria Heredia-Soto
Javier Escudero
María Miguel
Patricia Ruiz
Alejandro Gallego
Alberto Berjón
Alicia Hernández
Marta Martínez-Díez
Shuyu Zheng
4 more
Marta Mendiola

doi 10.3389/fonc.2022.862321

1,944 views
2 citations

REVIEW

Published on 01 Mar 2022

Effects of the Anti-Tumor Agents Trabectedin and Lurbinectedin on Immune Cells of the Tumor Microenvironment

Paola Allavena
Cristina Belgiovine
Elisabeth Digifico
Roberta Frapolli
Maurizio D’Incalci

doi 10.3389/fonc.2022.851790

3,465 views
16 citations

REVIEW

Published on 23 Feb 2022

Preclinical and Clinical Evidence of Lurbinectedin in Ovarian Cancer: Current Status and Future Perspectives

Lucia Musacchio
Carlo Maria Cicala
Vanda Salutari
Floriana Camarda
Maria Vittoria Carbone
Viola Ghizzoni
Elena Giudice
Camilla Nero
Maria Teresa Perri
3 more
Domenica Lorusso

doi 10.3389/fonc.2022.831612

1,893 views
6 citations

REVIEW

Published on 23 Feb 2022

The Role of Trabectedin in Soft Tissue Sarcoma

Tomoki Nakamura
Akihiro Sudo

doi 10.3389/fphar.2022.777872

6,679 views
14 citations

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Pharmacology of Anti-Cancer Drugs

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Frontiers in Pharmacology
- Pharmacology of Anti-Cancer Drugs
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Articles

Editorial: Trabectedin, lurbinectedin, and other marine-derived anticancer alkaloids on solid cancer: Mechanisms of action, clinical impact, and future perspectives

Trabectedin and lurbinectedin: Mechanisms of action, clinical impact, and future perspectives in uterine and soft tissue sarcoma, ovarian carcinoma, and endometrial carcinoma

From seaside to bedside: Current evidence and future perspectives in the treatment of breast cancer using marine compounds

DNA damage response and repair genes in advanced bone and soft tissue sarcomas: An 8-gene signature as a candidate predictive biomarker of response to trabectedin and olaparib combination

Determination of Extravasation Effects of Nal-Iri and Trabectedin and Evaluation of Treatment Options for Trabectedin Extravasation in a Preclinical Animal Model

Efficacy of Eribulin in Soft Tissue Sarcomas

Antitumoral Effect of Plocabulin in High Grade Serous Ovarian Carcinoma Cell Line Models

Effects of the Anti-Tumor Agents Trabectedin and Lurbinectedin on Immune Cells of the Tumor Microenvironment

Preclinical and Clinical Evidence of Lurbinectedin in Ovarian Cancer: Current Status and Future Perspectives

The Role of Trabectedin in Soft Tissue Sarcoma

Frontiers in Oncology

Participating Journals

Impact