Brain Aging in Health and Disease - A Single-Cell-Technology Approach

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ORIGINAL RESEARCH

Published on 27 Apr 2022

Bioinformatics Analysis of Publicly Available Single-Nuclei Transcriptomics Alzheimer’s Disease Datasets Reveals APOE Genotype-Specific Changes Across Cell Types in Two Brain Regions

Stella A. Belonwu
Yaqiao Li
Daniel G. Bunis
Arjun Arkal Rao
Caroline Warly Solsberg
Tomiko Oskotsky
Alice L. Taubes
Brian Grone
Kelly A. Zalocusky
2 more
Marina Sirota

Bioinformatics Analysis of Publicly Available Single-Nuclei Transcriptomics Alzheimer’s Disease Datasets Reveals APOE Genotype-Specific Changes Across Cell Types in Two Brain Regions

doi 10.3389/fnagi.2022.749991

4,062 views
5 citations

REVIEW

Published on 25 Mar 2022

Microglia and Neuroinflammation: Crucial Pathological Mechanisms in Traumatic Brain Injury-Induced Neurodegeneration

Fangjie Shao
Xiaoyu Wang
Haijian Wu
Qun Wu
Jianmin Zhang

Microglia and Neuroinflammation: Crucial Pathological Mechanisms in Traumatic Brain Injury-Induced Neurodegeneration

doi 10.3389/fnagi.2022.825086

16,108 views
128 citations

BRIEF RESEARCH REPORT

Published on 08 Nov 2021

Characterization of Alzheimer’s Disease-Associated Excitatory Neurons via Single-Cell RNA Sequencing Analysis

Fanghong Shao
Meiting Wang
Qi Guo
Bowen Zhang
Xiangting Wang

Characterization of Alzheimer’s Disease-Associated Excitatory Neurons via Single-Cell RNA Sequencing Analysis

doi 10.3389/fnagi.2021.742176

5,278 views
9 citations

ORIGINAL RESEARCH

Published on 28 May 2021

Amitriptyline Decreases GABAergic Transmission in Basal Forebrain Neurons Using an Optogenetic Model of Aging

Eunyoung Bang
Angelika Tobery
Karienn S. Montgomery
Annette S. Fincher
David J. Earnest
David A. Murchison
William H. Griffith

Amitriptyline Decreases GABAergic Transmission in Basal Forebrain Neurons Using an Optogenetic Model of Aging

doi 10.3389/fnagi.2021.673155

7,460 views
9 citations

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Frontiers in Aging Neuroscience

Frontiers in Aging Neuroscience

Alzheimer's Disease and Related Dementias
Neurocognitive Aging and Behavior
Cellular and Molecular Mechanisms of Brain-aging
Parkinson’s Disease and Aging-related Movement Disorders
Aging Neuroscience Archive
Neuroinflammation and Neuropathy

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