CRISPR Techniques for Biomedical Engineering and Functional Genomics

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REVIEW

Published on 28 Jan 2022

Utilization of CRISPR-Mediated Tools for Studying Functional Genomics in Hematological Malignancies: An Overview on the Current Perspectives, Challenges, and Clinical Implications

Maheswaran Solayappan
Adam Azlan
Kang Zi Khor
Mot Yee Yik
Matiullah Khan
Narazah Mohd Yusoff
Emmanuel Jairaj Moses

Utilization of CRISPR-Mediated Tools for Studying Functional Genomics in Hematological Malignancies: An Overview on the Current Perspectives, Challenges, and Clinical Implications

doi 10.3389/fgene.2021.767298

3,425 views
3 citations

ORIGINAL RESEARCH

Published on 23 Sep 2021

Assessment of Mosaicism and Detection of Cryptic Alleles in CRISPR/Cas9-Engineered Neurofibromatosis Type 1 and TP53 Mutant Porcine Models Reveals Overlooked Challenges in Precision Modeling of Human Diseases

Clifford Dustin Rubinstein
Dalton T. McLean
Brent P. Lehman
Jennifer J. Meudt
Dominic T. Schomberg
Kathy J. Krentz
Jamie L. Reichert
Mark B. Meyer
Marie Adams
1 more
Dhanansayan Shanmuganayagam

Assessment of Mosaicism and Detection of Cryptic Alleles in CRISPR/Cas9-Engineered Neurofibromatosis Type 1 and TP53 Mutant Porcine Models Reveals Overlooked Challenges in Precision Modeling of Human Diseases

doi 10.3389/fgene.2021.721045

3,259 views
8 citations

ORIGINAL RESEARCH

Published on 30 Aug 2021

Rapid CRISPR/Cas9 Editing of Genotype IX African Swine Fever Virus Circulating in Eastern and Central Africa

Hussein M. Abkallo
Nicholas Svitek
Bernard Oduor
Elias Awino
Sonal P. Henson
Samuel O. Oyola
Stephen Mwalimu
Nacrya Assad-Garcia
Walter Fuchs
1 more
Lucilla Steinaa

Rapid CRISPR/Cas9 Editing of Genotype IX African Swine Fever Virus Circulating in Eastern and Central Africa

doi 10.3389/fgene.2021.733674

5,129 views
15 citations

REVIEW

Published on 12 May 2021

Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing

Li Duan
Kan Ouyang
Xiao Xu
Limei Xu
Caining Wen
Xiaoying Zhou
Zhuan Qin
Zhiyi Xu
Wei Sun
Yujie Liang

Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing

doi 10.3389/fgene.2021.673286

59,401 views
201 citations

ORIGINAL RESEARCH

Published on 01 Apr 2021

CRISPR/Cas9-Mediated α-ENaC Knockout in a Murine Pancreatic β-Cell Line

Xue Zhang
Lihua Zhao
Runbing Jin
Min Li
Mei-Shuang Li
Rongfeng Li
Xiubin Liang

CRISPR/Cas9-Mediated α-ENaC Knockout in a Murine Pancreatic β-Cell Line

doi 10.3389/fgene.2021.664799

3,407 views
6 citations

REVIEW

Published on 28 Jan 2021

Gene Editing in Rabbits: Unique Opportunities for Translational Biomedical Research

Jie Xu
Jifeng Zhang
Dongshan Yang
Jun Song
Brooke Pallas
Chen Zhang
Jiafen Hu
Xuwen Peng
Neil D. Christensen
1 more
Y. Eugene Chen

Gene Editing in Rabbits: Unique Opportunities for Translational Biomedical Research

doi 10.3389/fgene.2021.642444

7,368 views
15 citations

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