About this Research Topic
Our genes play a role in the occurrence of diseases and the characteristics of complex traits. An understanding of the interplay of these genes and environmental factors is essential for the development of effective therapeutic approaches for the management of diseases. Unfortunately, the majority of the genetic studies have been performed in Europeans. The underrepresentation of ethnically diverse populations hinders our ability to completely comprehend the genetic architecture of complex traits and human disease, thereby worsening health inequalities in the underrepresented populations.
In this Research Topic, we are seeking high-quality Original Research and Review papers describing the genetics of diseases in understudied populations. These include African, Latin American, Indian and other indigenous populations. The specific themes of interest in this special issue include but not limited to:
- Genome-wide association studies;
- Gene-environment interactions;
- Polygenic/Genetic Risk Scores;
- Epigenetics;
- Pharmacogenomics;
- Microbiome studies.
In this Research Topic, we are seeking high-quality Original Research and Review papers describing the genetics of diseases in understudied populations. These include African, Latin American, Indian and other indigenous populations. The specific themes of interest in this special issue include but not limited to:
- Genome-wide association studies;
- Gene-environment interactions;
- Polygenic/Genetic Risk Scores;
- Epigenetics;
- Pharmacogenomics;
- Microbiome studies.
Keywords: GWAS, Genetics, Disease, Complex Traits, Indigenous populations
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
