About this Research Topic
With the demographic development resulting globally in an "aging population", the number of cardiovascular diseases is increasing year by year, and cardiovascular diseases rank the first mortality rate among all diseases. The prevalence rate of cardiovascular diseases will continue to increase in the next 10 years. The homeostasis balance of vascular structure and function is an important basis for life activities. Under the influence of various pathogenic factors such as inflammation, infection, environmental factors and personal lifestyle, the blood composition and shear stress of blood flow can be affected, causing endothelial dysfunction, platelet aggregation, fat deposition, inflammatory reaction, smooth muscle cell proliferation, etc., and then lead to hypertension, atherosclerosis, and intravascular restenosis, pulmonary hypertension and other vascular remodeling diseases.
Traditional Chinese (TM) has been proposed for the treatment for cardiovascular diseases, having shown potential in protecting vascular endothelial cells, regulating vascular microenvironment, and maintaining vascular homeostasis. Many formulae, herbs and natural products have been investigated for their effects in the prevention and treatment of cardiovascular diseases, such as Salvia miltiorrhiza, Pueraria lobata, Ligusticum chuanxiong, safflower, and Ginkgo biloba, and have the function of scavenging free radicals, inhibiting inflammatory reaction of blood vessels and improving hemorheology, which are widely used in clinical patients with cardiovascular diseases.
This Research Topic will focus on the effect and mechanisms of TM on vascular homeostasis and vascular remodeling. We seek to clarify the pathophysiological mechanism of TM on vascular homeostasis and remodeling from the gene, molecular, cellular, and overall levels, and find evidence of the characteristics and mechanisms of TM in vascular injury and repair. These works will help to find sensitive and effective early biomarkers, establish effective treatments, and find potential drug targets.
The articles of this Research Topic must be related to TM, and the traditional use must be described in the introduction and supported with bibliographical primary references. The methods in the articles must be reliable. Experimental outcomes should be linked to traditional therapeutic concepts.
In this Research Topic, we welcome the following article types: Original Research, Review, Mini-Review, Opinion, Hypothesis and Theory, or Methods, on the following subtopics, but not limited to:
• Basic research on regulation of vascular homeostasis and remodeling by TM.
• Evidence-based clinical study of TM in the management of cardiovascular diseases.
• Review of TM on vascular homeostasis and remodeling.
• Methods of vascular homeostasis and remodeling research.
This project aims to build upon the discoveries of Volume 1: The Potential Effect and Mechanism of Chinese Traditional Medicine on Vascular Homeostasis and Remodeling.
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One can find more information about the Article Types guidelines in the Ethnopharmacology section here.
All the manuscripts submitted to this project will be peer-reviewed and need to fully comply with the Four Pillars of Best Practice in Ethnopharmacology (you can freely download the full version here).
Traditional Chinese (TM) has been proposed for the treatment for cardiovascular diseases, having shown potential in protecting vascular endothelial cells, regulating vascular microenvironment, and maintaining vascular homeostasis. Many formulae, herbs and natural products have been investigated for their effects in the prevention and treatment of cardiovascular diseases, such as Salvia miltiorrhiza, Pueraria lobata, Ligusticum chuanxiong, safflower, and Ginkgo biloba, and have the function of scavenging free radicals, inhibiting inflammatory reaction of blood vessels and improving hemorheology, which are widely used in clinical patients with cardiovascular diseases.
This Research Topic will focus on the effect and mechanisms of TM on vascular homeostasis and vascular remodeling. We seek to clarify the pathophysiological mechanism of TM on vascular homeostasis and remodeling from the gene, molecular, cellular, and overall levels, and find evidence of the characteristics and mechanisms of TM in vascular injury and repair. These works will help to find sensitive and effective early biomarkers, establish effective treatments, and find potential drug targets.
The articles of this Research Topic must be related to TM, and the traditional use must be described in the introduction and supported with bibliographical primary references. The methods in the articles must be reliable. Experimental outcomes should be linked to traditional therapeutic concepts.
In this Research Topic, we welcome the following article types: Original Research, Review, Mini-Review, Opinion, Hypothesis and Theory, or Methods, on the following subtopics, but not limited to:
• Basic research on regulation of vascular homeostasis and remodeling by TM.
• Evidence-based clinical study of TM in the management of cardiovascular diseases.
• Review of TM on vascular homeostasis and remodeling.
• Methods of vascular homeostasis and remodeling research.
This project aims to build upon the discoveries of Volume 1: The Potential Effect and Mechanism of Chinese Traditional Medicine on Vascular Homeostasis and Remodeling.
---
One can find more information about the Article Types guidelines in the Ethnopharmacology section here.
All the manuscripts submitted to this project will be peer-reviewed and need to fully comply with the Four Pillars of Best Practice in Ethnopharmacology (you can freely download the full version here).
Keywords: Chinese Traditional Medicine, Vascular homeostasis, Vascular remodeling, Mechanism of action, Cardiovascular diseases
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
