About this Research Topic
This research topic will feature a compilation of Original Research articles, Brief Research Reports, Methods, Reviews, Mini-reviews and Opinion or Perspective articles that contribute to our better understanding of transcriptional regulation and TF function through the use of functional genomics in fungal pathogens and the assessment of the dynamics of TF regulatory networks during the interaction of pathogenic fungi with the host environment (or conditions mimicking the host environment). We believe that the content of this research topic will contribute to better resolving the global landscape of fungal transcriptional circuits and assessing their contribution to the armamentarium of virulence mechanisms used by fungi to thrive in their host niches. We more specifically welcome contributions to the following fields:
• Systems biology and functional genomics of transcriptional regulation in fungal pathogens of humans, animals and/or plants.
• TF functional analyses in pathogenic fungi with medical, environmental and/or agricultural importance using top-down approaches (e.g. ChIP-Seq, transcriptomics, etc.).
• Evolution of TF function in fungal pathogens with approaches that use non-pathogenic fungal species for comparative analyses (e.g. studies of TFs in pathogenic and non-pathogenic fungi to understand the evolution of transcriptional networks).
• Development of novel methods, technologies and algorithms/computational approaches addressing transcriptional regulation/TF function in fungal pathogens on a large-scale basis.
• Review articles addressing recent developments in the field of host-fungal pathogen interactions with a focus on TFs or transcriptional regulation.
• Perspective and opinion articles addressing functional genomics of TFs in pathogenic fungi.
Keywords: Functional Genomics, Transcriptional Regulatory Networks, Transcription Factors, Host-Fungal Interactions, Sensing/Response to Host-Environment
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.