About this Research Topic
In this Research Topic, we would like to focus on the technologies which are recently developed and are related to the comprehensive analysis of neural circuits, such as three-dimensional reconstruction of neural tissue either by light or electron microscopy, CLEM (correlative light- and electron- microscopy) and tissue clearing and synaptome analysis. Not only the experimental approach but also computational approaches, such as the auto-segmentation of electron microscope images by machine learning, should be included. Genome research to reveal the comprehensive analysis of gene expression pattern in the brain can also be the target of this Research Topic. Though these articles come from a relatively wide background, we hope that the readers can obtain not only useful information to proceed with their own projects but also to create new technologies for connectomical approaches, by combining various technologies introduced in this Research Topic. All article types accepted by the Journal are welcome for submission, including original research and reviews.
Keywords: connectome, microscopy, three-dimensional reconstruction, segmentation, synaptome
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.