About this Research Topic
Due to lack of understanding the disease, rarity, and difficulty in diagnosis, management for LCNEC remains unclear in several areas. Extrapolating from other lung cancer histologies, patients are currently treated like non-small cell lung cancer or SCLC. Because there are no established guidelines that address multi-disciplinary care of LCNEC, consensus approaches to manage LCNEC in clinics are warranted. We welcome prospective and retrospective original studies as well as literature reviews that provide readers with up-to-date management.
- Role of surgery and other non-medical management
- Adjuvant chemotherapy
- Systemic treatment (chemotherapy) in advanced stage
- New systemic treatments including targeted and immune checkpoint inhibitors
- Molecular characteristics of LCNEC
Keywords: Large Cell Neuroendocrine Carcinoma, lung cancer, chemotherapy, immunotherapy, surgery
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