Biomarkers and Pathogenesis of Alpha-Synuclein in Parkinson's Disease

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ORIGINAL RESEARCH

Published on 02 Jul 2021

PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway

  • Manikandan Samidurai
  • Bharathi N. Palanisamy
  • Alejandra Bargues-Carot
  • Monica Hepker
  • Naveen Kondru
  • Sireesha Manne
  • Gary Zenitsky
  • Huajun Jin
  • Vellareddy Anantharam
  • 1 more
  • Arthi Kanthasamy
PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway
doi 10.3389/fnagi.2021.661505
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  • 17 citations