About this Research Topic
Goal There has been a growing interest in exploring innovative methodology to optimize pediatric drug development, as well as individualized therapy. In this context, pharmacometrics presents a promising and valuable approach. Pharmacometrics is the science of quantitative pharmacology. In application to pediatrics, it involves primarily developmental pharmacokinetic and pharmacodynamic modeling and simulation, which can combine information from many diverse sources as drug characteristics, developmental clinical pharmacology, physiological changes during childhood, pediatric disease and statistics. In this Research Topic, we would like to highlight the value of model-based drug evaluation of antimicrobial agents in neonates, infants, children, and adolescents.
Scope and Information for Authors: model-based drug development of antimicrobial agents in the pediatric population; model-based individualized antimicrobial therapy in neonates, infants, children, and adolescents.
Type of manuscripts: Original Research; Brief Research Report; Review; Study Protocol.
Topic Editor Johannes N. van den Anker is the Chief Medical Officer at Reveragen Biopharma, as well as holding his positions at academic institutions. The other Topic Editor declares no competing interests with regard to the Research Topic subject.
Keywords: Pharmacokinetics, Pharmacometrics, Developmental Pharmacology, Children, Antimicrobial Agents
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