Aquatic Pharmacology

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Background

Infectious diseases are among the most serious threats to aquaculture development. As the aquaculture system becomes intensified and diversified, disease outbreaks are increasingly reported. However, currently only a few antimicrobial drugs are approved for use in aquatic animals compared to land animals and new drug development specifically for aquatic animals in the near future is unlikely. As a result, the current best option is to use available drugs wisely and sustainably. To preserve the efficacy of the currently available drugs while minimizing any drug-related adverse effects such as drug-resistance, tissue residue violation, toxicity to human consumers and non-target organisms and animals, scientific data supporting reasonable uses of compounds with pharmaceutical properties is required.

To our knowledge, out of more than 300 veterinary and aquatic science journals listed in the science citation index (SCI), there is no journal or single section in any journal that is dedicated specifically to pharmacological researches in aquatic species. Consequently, knowledge dissemination in the broad discipline of aquatic pharmacology falls significantly behind that of the land animals. Therefore, this Research Topic aims to fill the huge knowledge gaps between aquatic and land animal pharmacology in order to advance the health and wellbeing of aquatic species, and to create the first collection of its kind. With increasing importance in aquaculture industry, the launch of such medium to facilitate knowledge dissemination in the broad discipline of aquatic pharmacology is imminent.

With emphasis on the aquatic antimicrobials stated above, this Research Topic is devoted to scientific papers in all of the basic and clinical aspects of aquatic pharmacology and pharmacokinetics, providing a dependable platform to share concepts and findings pertaining to aquatic drug discovery, development, therapy and safety; it will cover areas including, but not limited to, the pharmacokinetics, pharmacodynamics, pharmacotherapeutics, pharmacogenetics, pharmacovigilance and immunopharmacology in all aquatic species of domestic, wild, and laboratory origin.

The goal of this Research Topic is to collect scientific information regarding the development and application of antimicrobial drugs (including but not limited to antibacterial, antifungal and antiparasitic agents) used in aquatic animals in the aspects of drug efficacy (both in vitro and in vivo), safety/toxicity, pharmacokinetics, metabolism and tissue residue depletion. As an alternative to the antimicrobial drug uses, application of other therapeutic agents like antiseptics/disinfectant (for external infection), herbal/algal extracts and their isolated compounds, or novel chemicals that show promising results for aquaculture application are welcome. However, immunomodulators, probiotics, vitamins, or other general health-promoting substances that are not aimed for disease treatment are outside the scope of this Research Topic. In addition, to minimize inappropriate uses of aquatic drugs, any research on prohibited or unapproved drugs such as malachite green, chloramphenicol, nitrofurans, colistin, vancomycin, higher generations of cephalosporins, etc. in food fish and shellfish is discouraged unless the authors can provide a good argument for such study.

Keywords: Aquatic, Pharmacology, Pharmacokinetics, Antimicrobial, Drug resistance, Drug Residues

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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