Proteoglycan biosynthesis and degradation in cancer: a key to proteoglycans structure and tumour microenvironment

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Articles

REVIEW

Published on 24 Jul 2014

The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics

Edward Hammond
Ashwani Khurana
Viji Shridhar
Keith Dredge

doi 10.3389/fonc.2014.00195

11,471 views
158 citations

OPINION

Published on 16 Jul 2014

Carbohydrate-Mediated Modulation of NK Cell Receptor Function: Structural and Functional Influences of Heparan Sulfate Moieties Expressed on NK Cell Surface

Michael Brusilovsky
Olga Radinsky
Rami Yossef
Kerry S. Campbell
Angel Porgador

doi 10.3389/fonc.2014.00185

4,248 views
16 citations

ORIGINAL RESEARCH

Published on 15 Apr 2014

Transcriptional Activity of Heparan Sulfate Biosynthetic Machinery is Specifically Impaired in Benign Prostate Hyperplasia and Prostate Cancer

Anastasia V. Suhovskih
Alexandra Y. Tsidulko
Olesya S. Kutsenko
Anna V. Kovner
Svetlana V. Aidagulova
Ingemar Ernberg
Elvira V. Grigorieva

doi 10.3389/fonc.2014.00079

4,835 views
18 citations

ORIGINAL RESEARCH

Published on 07 Feb 2014

Neuroendocrine Tumors Show Altered Expression of Chondroitin Sulfate, Glypican 1, Glypican 5, and Syndecan 2 Depending on Their Differentiation Grade

Olivia García-Suárez
Beatriz García
Iván Fernández-Vega
Aurora Astudillo
Luis M Quirós

doi 10.3389/fonc.2014.00015

4,764 views
33 citations

REVIEW

Published on 03 Feb 2014

Syndecans as Modulators and Potential Pharmacological Targets in Cancer Progression

Despoina Barbouri
Nikolaos Afratis
Chrisostomi Gialeli
Demitrios H Vynios
Achilleas D Theocharis
Nikos Karamanos

doi 10.3389/fonc.2014.00004

7,859 views
87 citations

REVIEW

Published on 14 Jan 2014

Post-Synthetic Regulation of HS Structure: The Yin and Yang of the Sulfs in Cancer

Romain R Vives
Amal Seffouh
Hugues Lortat-Jacob

doi 10.3389/fonc.2013.00331

5,115 views
74 citations

REVIEW

Published on 13 Jan 2014

Serglycin: At the Crossroad of Inflammation and Malignancy

Angeliki Korpetinou
Spyros S Skandalis
Vassiliki T Labropoulou
Gianna Smirlaki
Argyrios Noulas
Nikos K. Karamanos
ACHILLEAS D. THEOCHARIS

doi 10.3389/fonc.2013.00327

11,911 views
113 citations

REVIEW

Published on 19 Dec 2013

The Role of Syndecan-1 in Cellular Signaling and its Effects on Heparan Sulfate Biosynthesis in Mesenchymal Tumors

Tünde Szatmári
Katalin Dobra

doi 10.3389/fonc.2013.00310

20,497 views
60 citations

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Articles

The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics

Carbohydrate-Mediated Modulation of NK Cell Receptor Function: Structural and Functional Influences of Heparan Sulfate Moieties Expressed on NK Cell Surface

Transcriptional Activity of Heparan Sulfate Biosynthetic Machinery is Specifically Impaired in Benign Prostate Hyperplasia and Prostate Cancer

Neuroendocrine Tumors Show Altered Expression of Chondroitin Sulfate, Glypican 1, Glypican 5, and Syndecan 2 Depending on Their Differentiation Grade

Syndecans as Modulators and Potential Pharmacological Targets in Cancer Progression

Post-Synthetic Regulation of HS Structure: The Yin and Yang of the Sulfs in Cancer

Serglycin: At the Crossroad of Inflammation and Malignancy

The Role of Syndecan-1 in Cellular Signaling and its Effects on Heparan Sulfate Biosynthesis in Mesenchymal Tumors

Frontiers in Oncology

Participating Journals

Impact