DNA Methylation in Plants Associated with Abiotic Stress

  • 29k

    Total downloads

  • 121k

    Total views and downloads

Download PDFDownload EPUB

Submit your idea

Select the journal/section where you want your idea to be submitted:

Submit your manuscript summarySubmit your manuscript

About this Research Topic

Submission closed

Background

Methylation of DNA is an evolutionarily conserved modification. It is associated with heterochromatic structures. Together with histone modifications, DNA methylation generates unique patterns that support gene regulation, chromatin structuring, and repression of repetitive elements. This modification provides a heritable mark that can be propagated through mitosis and meiosis. The methylated region of DNA is recognized and interpreted by the epigenetic toolkit: the readers, writers, and erasers.

In most higher organisms, DNA methylation is restricted to symmetric cytosines. Due to the symmetry, the pattern can easily be propagated from one cell generation to the next after replication. Plants are the only organisms that display methylation of asymmetric cytosines, which represents a novel feature of regulation. This mechanism, defined as RNA-directed DNA methylation (RdDM), involves the presence of small regulatory RNAs as triggering molecules.

As several of the identified regulatory components of DNA methylation respond to the environmental conditions, the pattern of methylation in the genome can also change. Some of the environmental changes can occur from minutes to hours, others can affect longer periods like days, weeks, or even years for perennial plants. These changes can result in differential methylated regions in the genome (DMRs). If the DMR is located in the regulatory region of a gene, it might influence the transcriptional activity. In several cases, methylation of a promoter element leads to suppression of transcriptional activity, described as transcriptional gene silencing. In other cases, such as gene body methylation, the regulatory effect is not completely understood. It is generated as a footprint of post-transcriptional gene silencing. During the silencing process not only are 21mer siRNA generated but 24mer heterochromatic (hc)-siRNAs can also be generated. These hc-siRNAs lead via the RdDM process to methylate the region homologous to the silencing trigger. The question of whether methylation inside the coding sequence affects the rate of transcription requires further analysis. Meanwhile, transcription factors are described that require cis-element methylation for transcriptional activation. This finding contradicts the hypothesis of transcriptional gene silencing.

As the origin of most small RNAs is from repetitive DNA elements and retrotransposons, it is obvious that any environmental change that might lead to transcriptional reactivation of these elements has the potential to change the DNA methylation pattern. Therefore, for many environmental changes, differentially methylated genomic areas or sites are described. In some cases, these changes are affecting nearby genes and can cause changes in the phenotype. Although many factors involved in the molecular mechanism of DNA methylation pattern formation are identified, the complex interplay of environmentally induced DNA methylation change and phenotypic change is not always easy to address.

This Research Topic should collect examples of changes in DNA methylation caused by changes in the environment. This will shed light on the dynamics of pattern formation, the persistence of these patterns through the generations, and gene regulatory aspects.

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Topic editors

Frequently asked questions

  • Frontiers' Research Topics are collaborative hubs built around an emerging theme.Defined, managed, and led by renowned researchers, they bring communities together around a shared area of interest to stimulate collaboration and innovation.

    Unlike section journals, which serve established specialty communities, Research Topics are pioneer hubs, responding to the evolving scientific landscape and catering to new communities.

  • The goal of Frontiers' publishing program is to empower research communities to actively steer the course of scientific publishing. Our program was implemented as a three-part unit with fixed field journals, flexible specialty sections, and dynamically emerging Research Topics, connecting communities of different sizes and maturity.

    Research Topics originate from the scientific community. Many of our Research Topics are suggested by existing editorial board members who have identified critical challenges or areas of interest in their field.

  • As an editor, Research Topics will help you build your journal, as well as your community, around emerging, cutting-edge research. As research trailblazers, Research Topics attract high-quality submissions from leading experts all over the world.

    A thriving Research Topic can potentially evolve into a new specialty section if there is sustained interest and a growing community around it.

  • Each Research Topic must be approved by the specialty chief editor, and it falls under the editorial oversight of our editorial boards, supported by our in-house research integrity team. The same standards and rigorous peer review processes apply to articles published as part of a Research Topic as for any other article we publish.

    In 2023, 80% of the Research Topics we published were edited or co-edited by our editorial board members, who are already familiar with their journal's scope, ethos, and publishing model. All other topics are guest edited by leaders in their field, each vetted and formally approved by the specialty chief editor.

  • Publishing your article within a Research Topic with other related articles increases its discoverability and visibility, which can lead to more views, downloads, and citations. Research Topics grow dynamically as more published articles are added, causing frequent revisiting, and further visibility.

    As Research Topics are multidisciplinary, they are cross-listed in several fields and section journals – increasing your reach even more and giving you the chance to expand your network and collaborate with researchers in different fields, all focusing on expanding knowledge around the same important topic.

    Our larger Research Topics are also converted into ebooks and receive social media promotion from our digital marketing team.

     

  • Frontiers offers multiple article types, but it will depend on the field and section journals in which the Research Topic will be featured. The available article types for a Research Topic will appear in the drop-down menu during the submission process.

    Check available article types here 

  • Yes, we would love to hear your ideas for a topic. Most of our Research Topics are community-led and suggested by researchers in the field. Our in-house editorial team will contact you to talk about your idea and whether you’d like to edit the topic. If you’re an early-stage researcher, we will offer you the opportunity to coordinate your topic, with the support of a senior researcher as the topic editor. 

    Suggest your topic here 

  • A team of guest editors (called topic editors) lead their Research Topic. This editorial team oversees the entire process, from the initial topic proposal to calls for participation, the peer review, and final publications.

    The team may also include topic coordinators, who help the topic editors send calls for participation, liaise with topic editors on abstracts, and support contributing authors. In some cases, they can also be assigned as reviewers.

  • As a topic editor (TE), you will take the lead on all editorial decisions for the Research Topic, starting with defining its scope. This allows you to curate research around a topic that interests you, bring together different perspectives from leading researchers across different fields and shape the future of your field. 

     

    You will choose your team of co-editors, curate a list of potential authors, send calls for participation and oversee the peer review process, accepting or recommending rejection for each manuscript submitted.

  • As a topic editor, you're supported at every stage by our in-house team. You will be assigned a single point of contact to help you on both editorial and technical matters. Your topic is managed through our user-friendly online platform, and the peer review process is supported by our industry-first AI review assistant (AIRA).

  • If you’re an early-stage researcher, we will offer you the opportunity to coordinate your topic, with the support of a senior researcher as the topic editor. This provides you with valuable editorial experience, improving your ability to critically evaluate research articles and enhancing your understanding of the quality standards and requirements for scientific publishing, as well as the opportunity to discover new research in your field, and expand your professional network.

  • Yes, certificates can be issued on request. We are happy to provide a certificate for your contribution to editing a successful Research Topic.

  • Research Topics thrive on collaboration and their multi-disciplinary approach around emerging, cutting-edge themes, attract leading researchers from all over the world.

  • As a topic editor, you can set the timeline for your Research Topic, and we will work with you at your pace. Typically, Research Topics are online and open for submissions within a few weeks and remain open for participation for 6 – 12 months. Individual articles within a Research Topic are published as soon as they are ready.

    Find out more about our Research Topics

  • Our fee support program ensures that all articles that pass peer review, including those published in Research Topics, can benefit from open access – regardless of the author's field or funding situation.

    Authors and institutions with insufficient funding can apply for a discount on their publishing fees. A fee support application form is available on our website.

  • In line with our mission to promote healthy lives on a healthy planet, we do not provide printed materials. All our articles and ebooks are available under a CC-BY license, so you can share and print copies.

     

Impact

  • 121kTopic views
  • 89kArticle views
  • 29kArticle downloads
View impact