About this Research Topic
With the proven benefits of a personalized approach to medicine, it is crucial that all institutions worldwide start adopting these approaches in day-to-day healthcare delivery. As naturally expected, discrepancies have been noted, with some institutions leading the way in this field. The majority of the documented efforts (both research and clinical applications) are concentrated in the US and Europe, while not much information is available from different parts of the world, with few exceptions.
Therefore, the goal of this Research Topic is to shed more light onto worldwide PGx research and clinical applications with a focus on current accomplishments, challenges, lessons learnt, and opportunities for further advances in the field towards better clinical uptake of PGx.
Manuscripts submitted could be original research articles including surveys, reviews, case studies, short communications, opinions and perspectives related to any one or more of the following themes:
- Current availability and/or limitations of clinical PGx in specific countries or regions.
- Challenges of bringing PGx into clinical practice in specific countries or regions.
- Highly-powered PGx research in understudied populations or ethnicities.
- Applications of PGx clinical guidelines in understudied populations or ethnicities.
- Highly-powered candidate gene approaches vs. genome wide approaches for discovery of new markers in understudied populations or ethnicities.
- Integration of PGx in electronic medical records and clinical decision supports.
- Feasibility, cost/reimbursement and return of test results in preemptive genotyping vs. point of care genotyping
- Cost-effectiveness of PGx: case studies.
- Physicians related challenges: knowledge/education, attitudes, and practice/adoption/clinical workflow.
- Patients/society related challenges: expectations, knowledge, ethics/data protection concerns, legislation, counseling.
Keywords: Clinical, genotyping, ethnicities, reimbursement, education, society
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.