Environment
19 Oct 2022
Mushroom that grows on insects could help develop new anti-viral medications and cancer drugs
By Angharad Brewer Gillham, Frontiers science writer Image: bob.leccinum.Robert Kozak/Shutterstock.com Scientists studying the medicinal potential of a rare insect-eating mushroom have found a way to grow the elusive fungi in the lab, opening the way for the development of new anti-viral and cancer medications. The Cordyceps mushroom is best known for its gruesome eating habits: famously, its spores infect insects and kill them, growing into fully-fledged fruiting bodies that sprout from the insects’ flesh. But Cordyceps also has significant medicinal potential, containing a bioactive compound cordycepin which could potentially be developed into powerful new antiviral medications and cancer drugs. The mushrooms are rare in the wild, and until now, growing healthy Cordyceps in the lab has been a challenge which impedes scientific research – but Professor Mi Kyeong Lee of Chungbuk National University and her team including Dr Ayman Turk, publishing today in Frontiers in Microbiology, have found a way to grow these elusive fungi in a controlled setting without losing their potency. “Cordycepin is one of the cytotoxic nucleoside analogs with complementary therapeutic activities in anti-proliferation and anti-metastasis in cancer cells,” said Dr Lee, senior author of the study. “In addition, recent research findings strongly urge preclinical and clinical […]