22 news posts in Cancer

Smell receptor linked to prostate cancer progression

Blocking the olfactory receptor with drugs or scents might be a new prostate cancer treatment, say Duke researchers: Frontiers in Oncology

Neuroscience

13 Sep 2017

Preventing childhood deafness following treatment with life-saving cancer drugs

A new way to deliver steroids to the inner ear reduces hearing loss caused by chemotherapy, finds a study in Frontiers in Cellular Neuroscience.

Life sciences

26 May 2017

One Face Among Many in DNA Damage Response

The Research Topic, Published in Frontiers in Oncology & Frontiers in Genetics aims to give a comprehensive overview of our current understanding of ubiquitin and SUMO pathways in all aspects of DDR

Health

23 May 2017

High-energy charged particles: the beginning and end of cancer

The Research Topic, published in Frontiers in Oncology, consists of a collection of scientific articles investigating high-energy charged particles either for cancer treatment or for space radiation protection.

Life sciences

22 Mar 2017

Preventing long-term effects after drug holidays in cancer patients

Computer modelling suggests that drug combinations could protect from long-term drug level reductions in certain patients after a break from anti-cancer drug.

Health

26 May 2016

Linking our diets to changes in hormones and cancer

By Monica Favre, Frontiers science writer We’ve heard the phrase, “you are what you eat,” but recent research shows that what we are eating, how much we are eating and how we are living our lives could result in a cancer epidemic. “Our society is moving away from foods that our body has evolved to process, particularly in the western world. The problems come from simple energy balance, really,” said Professor Jeff Holly. “This is the first time in human evolution that we are eating caloric foods at higher frequency along with such sedentary life styles.” A professor of Clinical Sciences at the University of Bristol in the UK and the Field Chief Editor of Frontiers in Endocrinology, Holly’s work points to how nutrition is altering the signaling happening within the body. Based on his research and others in the field, the changes are occurring in the hormone molecules and their receptors, which work together to regulate the growth of cells. This could result in breast, prostate, colorectal and other cancers. “Our hormones are changing in relation to our lifestyles and diet. If you are getting the wrong nutrition, one that is triggering the hormone system to tell cells to […]

Life sciences

13 May 2016

Using precision-genetics in pigs to beat cancer

Because of their similarities to people, using new technology in pigs turns up as a valuable alternative to rodent models of cancer. By Mônica Favre, Frontiers Staff Science Writer The numbers are staggering: more than 40 % is the lifetime risk of developing cancer in the U.S., with only 66 % survival-rates 5 years after diagnosis, for all types of cancer. Trends suggest that in 2015, over 1.6 million new cases were diagnosed in the U.S., with over 580,000 deaths in consequence. These numbers emphasize the need to better understand and treat the various forms of the disease, but mouse models usually used in cancer research have given us limited answers. However, Senior Scientist Adrienne Watson and colleagues at Recombinetics and the University of Minnesota, say that pigs may turn out to be the best alternative models. “Many organ systems vary so greatly between rodents and humans that certain types of cancer cannot be accurately modelled,” says Watson, despite the major role mouse models have played in our understanding of the disease. The authors conclude that the five deadliest cancers in the U.S. cannot be modeled in rodents, or have ineffective models for identification of treatments that translate to the […]