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28 Jul 2021
Machine learning and knowledge engineering uncovers significant role of elevated blood glucose in severe Covid-19
By Colm Gorey, Frontiers’ Science Communications Manager A digital reconstruction of SARS-CoV-2 primary infection in the lungs. Image: Blue Brain Project/EPFL 2005-2021. All rights reserved Why does Covid-19 present itself more severe in some patients but not in others? The question has puzzled researchers and clinicians since the start of the pandemic, but now new research from the EPFL Blue Brain Project may have found a major clue to solving the mystery thanks to machine learning. Analyzing data extracted from 240,000 open access scientific papers, the findings of a paper published in Frontiers revealed the previously undiscovered roles elevated blood glucose levels have in the severity of Covid-19. What makes one person more at risk of developing severe Covid-19 than someone else? While it is widely accepted that elderly people are the most at-risk during the current pandemic, many young, seemingly healthy people have also been hospitalized by the disease. A number of preexisting conditions are known to contribute to the severity of the disease – such as diabetes, obesity and hypertension – but a more recent finding has highlighted the impact of blood glucose levels among both diabetic and non-diabetic people. Yet the role that glucose plays in the […]