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422 news posts in Life sciences

Life sciences

01 Feb 2023

Medicines that modify the circadian clock might help heal scars more cleanly

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Scientists determined that compounds which play key roles in both collagen synthesis and circadian management can be used to make wounds on cell samples heal more quickly and effectively, offering promise for treatments to prevent problem scarring in the future. Healing often leaves a scar. But the role of the scar itself in healing is often underestimated: a scar that doesn’t heal cleanly can be painful or upsetting or affect the range of movement of the affected body part. It may even require further surgical treatment. Now, scientists based at the University of California Los Angeles have found that compounds which target the circadian clock and affect the synthesis of collagen — a protein which is important for skin repair — could improve scar healing. “Our aim was to find compounds that were able to increase the rate at which dermal wounds heal while mitigating the formation of hypertrophic scars,” said Dr Akishige Hokugo, corresponding author of a study published to Frontiers in Medicine. “Scars can result in emotional distress following normal wound healing by serving as permanent reminders of the initial incident. Accounting for additional revision procedures, extended hospital stays, and […]

Life sciences

31 Jan 2023

Songbird species work together to mob predator owls, but only strike when the time is right

By Mischa Dijkstra, Frontiers science writer Northern pygmy owl, Glaucidium gnoma. Image credit: W Douglas Robinson Scientists have now shown that songbirds don’t just flee from their predator, the northern pygmy owl: they sometimes actively seek them out to aggressively mob them. But the likelihood of mobbing wasn’t constant: it was highest during late summer and autumn when the owls mostly prey on young birds instead of mammals, and at low altitudes, where the owls are most common. The likelihood of mobbing also increased when there were more songbirds around to dilute the individual risk. The authors conclude that songbirds can tell when the risk of predation from northern pygmy owls is greatest, and mostly ignore these owls at other times of the year. Fleeing isn’t the only way by which songbirds can protect themselves against predators. Many songbird species are known to engage in mobbing, where they gather aggressively around a bird of prey, flying rapidly while making stereotypic movements and loud vocalizations. Mobbing is risky for both parties: birds of preys have been observed to attack their mobbers, while cases are known of birds of prey getting injured by mobbing songbirds. Read original article Download original article (pdf) […]

Life sciences

24 Jan 2023

‘Golden boy’ mummy was protected by 49 precious amulets, CT scans reveal

By Mischa Dijkstra, Frontiers science writer The ‘Golden boy’ digitally unwrapped, stepwise. Image credit: SN Saleem Scientists used CT scans to ‘digitally unwrap’ the approximately 2,300-year-old undisturbed mummy of a teenage boy of high socioeconomic status. The body was equipped with 49 amulets of 21 different types, many of which were made of gold, which had been carefully placed on or inside the body. These included a two-finger amulet next to the uncircumcised penis, a golden heart scarab placed inside the thoracic cavity, and a golden tongue inside the mouth. He was clad in sandals and garlanded with ferns, with ritual significance. This mummy is a showcase of Egyptian beliefs about death and the afterlife during the Ptolemaic period. The ancient Egyptians believed that when we died, our spiritual body sought out an afterlife similar to this world. But entry into this afterlife wasn’t guaranteed: it first required a perilous journey through the underworld, followed by an individual last judgment. For this reason, relatives and embalmers did everything they could to ensure that their loved one might reach a happy destination. Here, scientists from Egypt used computerized tomography (CT) to ‘digitally unwrap’ the intact, never-opened mummy of a 2,300-year-old teenage […]

Life sciences

19 Jan 2023

Microalgae could be the future of sustainable superfood in a rapidly changing world, study finds

By Peter Rejcek, science writer The global population recently hit eight billion people. Yet climate change and human environmental impacts threaten our long-term food security. Researchers at the University of California, San Diego, recently published a scientific review demonstrating that microalgae and other microscopic, plant-like organisms could help feed the world’s growing population more sustainably than current agricultural systems. Algae. It’s what’s for dinner. This variation on the iconic US advertising slogan from the beef industry may sound funny, but it’s no joke that the current agriculture system is a major source of greenhouse gas emissions and environmental pollution. In turn, the climate crisis and ecosystem degradation threaten long-term food security for billions of people around the world. Researchers at the University of California, San Diego (UCSD), believe algae could be a new kind of superfood thanks to its high protein and nutrition content. They make their case in a paper recently published in the journal Frontiers in Nutrition that examines the current scientific literature on microalgae, a catch-all term for the thousands of microscopic algal species and other photosynthetic organisms like cyanobacteria found in various aquatic environments. A more efficient food source The review highlights the current technologies for […]

Life sciences

17 Jan 2023

From pylons to pandas: 5 Frontiers articles you won’t want to miss

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com At Frontiers, we bring some of the world’s best research to a global audience. But with tens of thousands of articles published each year, many often fly under the radar. Here are just five amazing papers you may have missed. Building better-looking pylons Pylons help support essential amenities – but they can be an eyesore. Italian scientists led by Dr Luca Di Angelo at University of L’Aquila investigated the best way to build a pylon with less visual impact on the landscape. As visual impact is subjective, reducing it requires consultation with residents who will see the pylons every day. But designs invented by residents without technical knowledge may not be able to meet safety standards. Di Angelo and colleagues used the development of new electrical pylons in the coastal regions of Italy to test a novel method of integrating visual impact minimization with the design process. They identified shapes which were related to the geography and culture of the area and streamlined enough for pylon design, and surveyed Italians from different coastal regions to determine which shapes were considered most recognizable and representative. A sail was chosen, and models were developed […]

Life sciences

16 Jan 2023

Our toilets can yield excellent alternatives for widespread polluting fertilizers

By Mischa Dijkstra, Frontiers science writer Scientists show that the yield of cabbages grown on soils supplied with two modern nitrified urine fertilizers recycled from human urine is approximately equal to the yield when soils are fertilized with commercial vinasse. The exclusive use of compost recycled from human feces gave a slightly lower yield, but such compost is expected to give extra carbon to soils when combined with nitrified urine fertilizers. Importantly, pharmaceuticals in feces ended up in the edible plant parts only in negligible amounts, implying that fertilizers recycled from human excreta are not only productive but also safe. To tackle the climate crisis, biodiversity loss, and pollution, humanity will need to move to a circular economy, where all resources are recycled. Why not recycle our own body waste too as fertilizer, provided there is no risk that harmful microbes or traces from pharmaceuticals end up in the consumed crops? Most nutrients needed for plant growth occur in human urine and feces. Urine is especially rich in nitrogen and potassium, and also contains trace amounts of metals such as boron, zinc, and iron. Feces could in theory supply other nutrients such as phosphorus, calcium, and magnesium or valuable organic […]

Life sciences

09 Jan 2023

Eating almonds daily boosts exercise recovery molecule by 69% among ‘weekend warriors’

By Mischa Dijkstra, Frontiers science writer A new randomized controlled trial showed that participants who daily ate 57g almonds over four weeks had a 69% higher level of the beneficial oxylipin molecule 12,13-dihydroxy-9Z-octadecenoic acid in their blood after a 90 minute session of eccentric exercise than control volunteers. In contrast, they had a 40% lower level of the mildly toxic 9,10-Dihydroxy-12-octadecenoic acid in their blood after exercise than control participants. The authors conclude that daily consumption of almonds changes the metabolism to recover faster after strenuous exercise. For those who exercise regularly, eating almonds each day might be the ideal new year’s resolution. A randomized controlled trial in Frontiers in Nutrition showed that female and male participants who ate 57g almonds daily for one month had more of the beneficial fat 12,13-dihydroxy-9Z-octadecenoic acid (12,13-DiHOME) in their blood immediately after a session of intense exercise than control participants. This molecule, a so-called oxylipin (oxidized fat) is synthetized from linoleic acid by brown fat tissue, and has a beneficial effect on metabolic health and energy regulation. Corresponding author Dr David C Nieman, a professor and director of the Appalachian State University Human Performance Laboratory at the North Carolina Research Campus, said: “Here […]

Life sciences

16 Dec 2022

Screening a puppy’s DNA methylome may help predict how energetic or fearful they will be

By Mischa Dijkstra, Frontiers science writer Scientists found that differences in the epigenome, in particular the DNA methylome, are predictably associated with differences in the temperament of dogs, especially their energy and fearfulness. The DNA methylome predicted these traits better than Single-Locus Polymorphisms or age. In future, breeders could screen the epigenome of puppies to find the best candidates for companion or service dogs. Anyone who’s ever had a dog knows how different one can be from another. For example, they can be reserved or friendly, playful or calm, fearful or bold, and prone to bark or fetch or not. Research has shown that some of these differences are genetically determined. But even within dog breeds, where line breeding and artificial selection have led to the loss of much of the original genetic variation, the behavior of individuals can differ widely. Now, researchers show that part of the differences in temperament – in particular  their ‘energy’ level and fear-related behaviors – depend on acquired differences in the epigenome. The epigenome, an individual’s unique set of chemical tags on DNA and its associated histone complexes (nucleosomes), can dial the expression of local genes up or down. Because the epigenome is known […]

Life sciences

09 Dec 2022

Evolution of bat wings and calls through ‘foraging syndromes’ allows diversity to flourish

By Mischa Dijkstra, Frontiers science writer Egyptian slit-faced bats, Nycteris thebaica In a new study, scientists show that the wing shape and the echolocation frequency of bats are tightly linked across species. This pattern could only be identified because of the large dataset in the present study, which allowed the authors to look beyond the effect of bat family on these traits. The results mean that wing shape and echolocation frequency have jointly evolved in response to foraging ecology, yielding an optimal combination of traits or ‘foraging syndrome’ in each habitat. Bats are an evolutionary success story. With approximately 1,400 species living today, they thrive in every environment except the polar regions. They come in a remarkable range of sizes, from the golden-crowned flying fox with a mass of 1.2 kg and a wingspan of 171 cm, to Kitti’s hog-nosed ‘bumblebee’ bat with a mass of 2 g and a wingspan of 33 cm. The frequencies that bats emit during echolocation are also highly variable, ranging from 11 kHz to 212 kHz. But what has driven the evolution of this extraordinary diversity? “Here we show with that among bat species, there is a close correspondence between wing shape and the […]

Life sciences

07 Dec 2022

Could new cancer drugs come from potatoes and tomatoes?

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Polish scientists revealed the potential for new cancer drugs to be formulated from bioactive compounds found in plants from the genus Solanum, like potatoes and aubergines. Everyone knows someone who has had cancer. In 2020, around 19m new cases — and around 10m deaths — were registered worldwide. Treatments are improving all the time but can damage healthy cells or have severe side-effects which are hard on patients; in the search for new, more targeted cancer drugs, traditional medicine offers many possible candidates. A team of Polish scientists led by Magdalena Winkiel at Adam Mickiewicz University, publishing today in Frontiers in Pharmacology, reviewed the bioactive compounds called glycolalkaloids that are found in many vegetables that are household names, like potatoes and tomatoes, to demonstrate their potential to treat cancer. “Scientists around the world are still searching for the drugs which will be lethal to cancer cells but at the same time safe for healthy cells,” said Winkiel. “It is not easy despite the advances in medicine and powerful development of modern treatment techniques. That is why it might be worth going back to medicinal plants that were used years ago with success […]

Life sciences

23 Nov 2022

World’s heaviest flying bird may be self-medicating on plants used in traditional medicine

By Mischa Dijkstra, Frontiers science writer Great bustard male displaying on lek. Image credit: Carlos Palacín Researchers show that great bustards in Spain prefer to eat two plant species with compounds active in vitro against protozoa, nematodes, and fungi: corn poppies and purple viper’s bugloss. Males, who spend much time and energy on sexual displays during the mating season, have a stronger preference for these plants than females, and more so during the mating season than at other times of the year. The authors thus consider great bustards as prime candidates for non-human animals that self-medicate, but stress that more research is needed to definitively prove this. If you see a great bustard (Otis tarda) in the wild, you’re unlikely to forget it. Massive, colorful, and impossible to mistake, they are the heaviest birds living today capable of flight, with the greatest size difference between the sexes. They are also ‘lek breeders’, where males gather at chosen sites to put on an audiovisual show for the visiting females, who choose a mate based on his appearance and the quality of his showbirdship. But now, a study in Frontiers in Ecology and Evolution suggests that great bustards have another claim to […]

Life sciences

11 Nov 2022

Having good friendships may make for a healthier gut microbiome

By Mischa Dijkstra, Frontiers science writer Grooming rhesus macaques on Cayo Santiago. Image credit: Lauren Brent Researchers show for the first time that monkeys that are more sociable – eg, grooming or being groomed more often, and with more grooming partners – have a healthier gut microbiome. For example, they have more of the beneficial bacteria Faecalibacterium and Prevotella, and fewer of the typically pathogenic bacteria Streptococcus. This is further evidence that in primates, social connectedness translates into good physical and mental health, and vice versa. Social connections are essential for good health and wellbeing in social animals, such as ourselves and other primates. There is also increasing evidence that the gut microbiome – through the so-called ‘gut-brain axis’ – plays a key role in our physical and mental health and that bacteria can be transmitted socially, for example through touch. So how does social connectedness translate into the composition and diversity of the gut microbiome? That’s the topic of a new study in Frontiers in Microbiology on rhesus macaques, Macaca mulatta. Lead author Dr Katerina Johnson, a research associate at the Department of Experimental Psychology and the Department of Psychiatry of the University of Oxford, said: “Here we show […]

Life sciences

04 Nov 2022

From ghost gear to microbe memories: 4 Frontiers articles you won’t want to miss

by Angharad Brewer Gillham, Frontiers science writer Image: Shutterstock.com At Frontiers, we bring some of the world’s best research to a global audience. But with tens of thousands of articles published each year, many often fly under the radar. Here are just four amazing papers you may have missed. The hunt for ghost gear 25-30% of the plastic waste in the sea is lost fishing gear, or ‘ghost gear’, some of it now up to 60 years old. This ghost gear devastates the environment not only through continuing to trap fish, but also by shedding microplastics into the environment which then enter the food chain. Once it sinks as far as the sea floor, it becomes invisible from above – a hidden threat to the marine ecosystem. A team led by Andrea Stolte from the World Wildlife Foundation, writing in Frontiers in Marine Science, reported a successful ghost-hunting collaboration between fisherfolk, scientists, and divers in the Baltic Sea. This coalition of stakeholders had several options for hunting down the ghost gear. Traditionally, when lost gear is spotted, fisherfolk use search hooks and other similar tools to try to retrieve it. However, this proved to be inefficient and damaging to the […]

Life sciences

02 Nov 2022

Italian researchers discover new recipe for extending shelf life of fresh pasta by 30 days

By Peter Rejcek, science writer Image credit: Raimunda Losantos / Shutterstock.com Pasta is one of the most popular food staples in the world, but fresh pasta has a limited shelf life. Scientists in Italy have cooked up a novel process for preventing or delaying spoilage by changing packaging protocols, as well as adding antimicrobial probiotics to the dough. Not only does this new method extend storage of fresh pasta by 30 days, it helps reduce food waste. Pasta is serious business in Italy, with reportedly more than 300 specific forms known by some 1,300 names. There is even a 55-year-old ‘pasta law’ that governs its production and manufacture. But that doesn’t mean the beloved food staple is shut off from innovation. ► Read original article► Download original article (pdf) Now, Italian researchers have cooked up a new process for extending the shelf life of fresh pasta by 30 days, using a novel packaging process that also involves applying bioprotective probiotic cultures to the dough. They published this new recipe for better preserving fresh pasta in the journal Frontiers in Microbiology. The problem with fresh pasta Most fresh pasta sold in stores today is produced through an industrial process that includes heat-treating the […]

Life sciences

26 Oct 2022

‘Virtual autopsy’ identifies a 17th century mummified toddler hidden from the sun

by Angharad Brewer Gillham, Frontiers science writer Image: Riderfoot/Shutterstock.com Scientists used a ‘virtual autopsy’ to examine the mummy of a child found in an aristocratic family crypt, revealing him most probably as Reichard Wilhelm (1625-1626). Despite his wealthy background, the child experienced extreme nutritional deficiency and a tragically early death from pneumonia. A team of scientists based in Germany have examined a 17th century child mummy, using cutting-edge science alongside historical records to shed new light on Renaissance childhood. The child was found in an aristocratic Austrian family crypt, where the conditions allowed for natural mummification, preserving soft tissue that contained critical information about his life and death. Curiously, this was the only unidentified body in the crypt, buried in an unmarked wooden coffin instead of the elaborate metal coffins reserved for the other members of the family buried there. The team, led by Dr Andreas Nerlich of the Academic Clinic Munich-Bogenhausen, carried out a virtual autopsy and radiocarbon testing, and examined family records and key material clues from the burial, to try to understand who the child was and what his short life looked like. “This is only one case,” said Nerlich, lead author of the paper published today […]