413 news posts in Life sciences

Life sciences

07 Dec 2022

Could new cancer drugs come from potatoes and tomatoes?

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Polish scientists revealed the potential for new cancer drugs to be formulated from bioactive compounds found in plants from the genus Solanum, like potatoes and aubergines. Everyone knows someone who has had cancer. In 2020, around 19m new cases — and around 10m deaths — were registered worldwide. Treatments are improving all the time but can damage healthy cells or have severe side-effects which are hard on patients; in the search for new, more targeted cancer drugs, traditional medicine offers many possible candidates. A team of Polish scientists led by Magdalena Winkiel at Adam Mickiewicz University, publishing today in Frontiers in Pharmacology, reviewed the bioactive compounds called glycolalkaloids that are found in many vegetables that are household names, like potatoes and tomatoes, to demonstrate their potential to treat cancer. “Scientists around the world are still searching for the drugs which will be lethal to cancer cells but at the same time safe for healthy cells,” said Winkiel. “It is not easy despite the advances in medicine and powerful development of modern treatment techniques. That is why it might be worth going back to medicinal plants that were used years ago with success […]

Life sciences

23 Nov 2022

World’s heaviest flying bird may be self-medicating on plants used in traditional medicine

By Mischa Dijkstra, Frontiers science writer Great bustard male displaying on lek. Image credit: Carlos Palacín Researchers show that great bustards in Spain prefer to eat two plant species with compounds active in vitro against protozoa, nematodes, and fungi: corn poppies and purple viper’s bugloss. Males, who spend much time and energy on sexual displays during the mating season, have a stronger preference for these plants than females, and more so during the mating season than at other times of the year. The authors thus consider great bustards as prime candidates for non-human animals that self-medicate, but stress that more research is needed to definitively prove this. If you see a great bustard (Otis tarda) in the wild, you’re unlikely to forget it. Massive, colorful, and impossible to mistake, they are the heaviest birds living today capable of flight, with the greatest size difference between the sexes. They are also ‘lek breeders’, where males gather at chosen sites to put on an audiovisual show for the visiting females, who choose a mate based on his appearance and the quality of his showbirdship. But now, a study in Frontiers in Ecology and Evolution suggests that great bustards have another claim to […]

Life sciences

11 Nov 2022

Having good friendships may make for a healthier gut microbiome

By Mischa Dijkstra, Frontiers science writer Grooming rhesus macaques on Cayo Santiago. Image credit: Lauren Brent Researchers show for the first time that monkeys that are more sociable – eg, grooming or being groomed more often, and with more grooming partners – have a healthier gut microbiome. For example, they have more of the beneficial bacteria Faecalibacterium and Prevotella, and fewer of the typically pathogenic bacteria Streptococcus. This is further evidence that in primates, social connectedness translates into good physical and mental health, and vice versa. Social connections are essential for good health and wellbeing in social animals, such as ourselves and other primates. There is also increasing evidence that the gut microbiome – through the so-called ‘gut-brain axis’ – plays a key role in our physical and mental health and that bacteria can be transmitted socially, for example through touch. So how does social connectedness translate into the composition and diversity of the gut microbiome? That’s the topic of a new study in Frontiers in Microbiology on rhesus macaques, Macaca mulatta. Lead author Dr Katerina Johnson, a research associate at the Department of Experimental Psychology and the Department of Psychiatry of the University of Oxford, said: “Here we show […]

Life sciences

04 Nov 2022

From ghost gear to microbe memories: 4 Frontiers articles you won’t want to miss

by Angharad Brewer Gillham, Frontiers science writer Image: Shutterstock.com At Frontiers, we bring some of the world’s best research to a global audience. But with tens of thousands of articles published each year, many often fly under the radar. Here are just four amazing papers you may have missed. The hunt for ghost gear 25-30% of the plastic waste in the sea is lost fishing gear, or ‘ghost gear’, some of it now up to 60 years old. This ghost gear devastates the environment not only through continuing to trap fish, but also by shedding microplastics into the environment which then enter the food chain. Once it sinks as far as the sea floor, it becomes invisible from above – a hidden threat to the marine ecosystem. A team led by Andrea Stolte from the World Wildlife Foundation, writing in Frontiers in Marine Science, reported a successful ghost-hunting collaboration between fisherfolk, scientists, and divers in the Baltic Sea. This coalition of stakeholders had several options for hunting down the ghost gear. Traditionally, when lost gear is spotted, fisherfolk use search hooks and other similar tools to try to retrieve it. However, this proved to be inefficient and damaging to the […]

Life sciences

02 Nov 2022

Italian researchers discover new recipe for extending shelf life of fresh pasta by 30 days

By Peter Rejcek, science writer Image credit: Raimunda Losantos / Shutterstock.com Pasta is one of the most popular food staples in the world, but fresh pasta has a limited shelf life. Scientists in Italy have cooked up a novel process for preventing or delaying spoilage by changing packaging protocols, as well as adding antimicrobial probiotics to the dough. Not only does this new method extend storage of fresh pasta by 30 days, it helps reduce food waste. Pasta is serious business in Italy, with reportedly more than 300 specific forms known by some 1,300 names. There is even a 55-year-old ‘pasta law’ that governs its production and manufacture. But that doesn’t mean the beloved food staple is shut off from innovation. ► Read original article► Download original article (pdf) Now, Italian researchers have cooked up a new process for extending the shelf life of fresh pasta by 30 days, using a novel packaging process that also involves applying bioprotective probiotic cultures to the dough. They published this new recipe for better preserving fresh pasta in the journal Frontiers in Microbiology. The problem with fresh pasta Most fresh pasta sold in stores today is produced through an industrial process that includes heat-treating the […]

Life sciences

26 Oct 2022

‘Virtual autopsy’ identifies a 17th century mummified toddler hidden from the sun

by Angharad Brewer Gillham, Frontiers science writer Image: Riderfoot/Shutterstock.com Scientists used a ‘virtual autopsy’ to examine the mummy of a child found in an aristocratic family crypt, revealing him most probably as Reichard Wilhelm (1625-1626). Despite his wealthy background, the child experienced extreme nutritional deficiency and a tragically early death from pneumonia. A team of scientists based in Germany have examined a 17th century child mummy, using cutting-edge science alongside historical records to shed new light on Renaissance childhood. The child was found in an aristocratic Austrian family crypt, where the conditions allowed for natural mummification, preserving soft tissue that contained critical information about his life and death. Curiously, this was the only unidentified body in the crypt, buried in an unmarked wooden coffin instead of the elaborate metal coffins reserved for the other members of the family buried there. The team, led by Dr Andreas Nerlich of the Academic Clinic Munich-Bogenhausen, carried out a virtual autopsy and radiocarbon testing, and examined family records and key material clues from the burial, to try to understand who the child was and what his short life looked like. “This is only one case,” said Nerlich, lead author of the paper published today […]

Life sciences

24 Oct 2022

CO2 ventilation breakthrough could turn city rooftops into bumper vegetable gardens

by Angharad Brewer Gillham, Frontiers science writer Image: Shutterstock.com Scientists find that expelled air from ventilation systems can make corn and spinach grow taller and larger, recycling CO2-rich indoor air to fertilize edible plants. As the world’s cities grow, the hunt is on for ways to make them greener, more sustainable, and more livable. Rooftop farms and gardens that take advantage of underutilized roof space are a popular option, providing new food resources while simultaneously cooling the surrounding area, increasing building insulation, and improving air quality. But the conditions on rooftops — greater solar radiation, more wind exposure, lesser soil moisture — often mean that plants are smaller and less healthy. A team led by Dr Sarabeth Buckley, now at the University of Cambridge, theorized that repurposing the CO2 from building exhaust as a kind of fertilizer might help counter some of these challenges. To explore this, they grew corn and spinach on the roof of a campus building at Boston University. “We wanted to test whether there is an untapped resource inside buildings that could be used to make plants grow larger in rooftop farms,” said Buckley, whose team named their experimental garden BIG GRO and published their work […]

Life sciences

21 Oct 2022

Secret behind spectacular blooms in world’s driest desert is invisible to human eyes

By Mischa Dijkstra, Frontiers science writer The 2021 ‘desierto florido’ near Caldera, Chile. The purple flowers are the pussypaw Cistanthe longiscapa (family Montiaceae), the object of this study. Image credit: Oven Pérez-Nates A ‘desierto florido’ mass bloom happened in the northern Atacama desert in 2021, which was even visible from space. Researchers used advanced imaging techniques to measure the variation in flower color and pattern for the dominant species, the pussypaw Cistanthe longiscapa. They found that this variation is much greater when viewed by the UV-sensitive eyes of hymenopteran pollinators, and caused by differences in the mix of betalain pigments in the petals. Evolution is probably ongoing, driven by the species-specific visual preferences of pollinators, which could ultimately lead to new species. The Atacama desert, which stretches for approximately 1,600 km along the western coast of the cone of South America, is the driest place on Earth. Some weather stations there have never recorded rainfall throughout their existence. But it‘s far from barren: many species live here that occur nowhere else, adapted to its extreme conditions. And approximately every five to 10 years, from September to mid-November, the Atacama hosts one of the most spectacular sights of the natural world: […]

Life sciences

07 Oct 2022

Scientists peel back ancient layers of banana DNA to reveal mystery ancestors

By Mischa Dijkstra, Frontiers science writer Researchers compare the genomes of more than 200 wild and domesticated varieties of bananas and show that three extra ancestors, either subspecies or distinct species, must have been involved in the domestication process. They also deduce the geographic regions in Australasia where these mystery ancestors lived. If they haven’t gone extinct, they are likely threatened and it’s urgent to find and protect them, to preserve genetic diversity that could help breed better bananas. Bananas are thought to have been first domesticated by people 7,000 years ago on the island of New Guinea. But the domestication history of bananas is complicated, while their classification is hotly debated, as boundaries between species and subspecies are often unclear. Now, a study in Frontiers in Plant Science shows that this history is even more complex than previously thought. The results confirm that the genome of today’s domesticated varieties contains traces of three extra, as yet unknown ancestors. ► Read original article► Download original article (pdf) “Here we show that most of today’s diploid cultivated bananas that descend from the wild banana M. acuminata are hybrids between different subspecies. At least three extra wild ‘mystery ancestors’ must have contributed to this […]

Life sciences

27 Sep 2022

Sugary poo could be used to lure destructive plant pests to their doom

By K.E.D. Coan, science writer Aggregation of spotted lanternflies, Lycorma delicatula. Image credit: Jana Shea / Shutterstock.com Spotted lanternflies send signals with their honeydew excretions, shows a new study. Scientists are researching how this damaging invasive species communicates in order to better manage the pest problem. This research provides knowledge of how these insects find each other, as well as the first evidence to show that these signals appear sex-specific. Spotted lanternflies communicate through their smelly excretions, called honeydew, reports a new study in Frontiers in Insect Science. This invasive species has been impacting crops in the northeastern US, but little is known about how these insects locate each other for reproduction or feeding. According to this latest research, the insects’ honeydew emits several airborne chemicals that attract other lanternflies. Surprisingly, these effects are sex-specific, which may be the first known case of such signals in insects known as planthoppers. “This research is important because the first step to managing any pest is to understand their biology and behavior,” said Dr Miriam Cooperband of the United States Department of Agriculture Animal and Plant Health Inspection Service, Plant Protection and Quarantine Division (USDA APHIS PPQ) in the US. “As we learn […]

Life sciences

23 Sep 2022

Acquired immunity against random food allergens may protect some lucky people against Covid-19

By Conn Hastings, science writer A new study has investigated the potential of proteins in common foods to elicit protection against SARS-CoV-2. The researchers found that antibodies that bind SARS-CoV-2 can also bind to proteins in certain foods, viruses, vaccines, and common bacteria. The results suggest that exposure to such agents may confer some protective immunity to Covid-19, but further research is needed to confirm this. Why do some people become seriously ill with Covid-19, while others have no symptoms at all? The answer may lie in the proteins our immune system has previously been exposed to. A recent study in open-access journal Frontiers in Immunology finds that common foods, vaccines, bacteria and viruses may all prime our immune system to attack SARS-CoV-2, the virus that causes Covid-19. These agents all contain proteins that are similar to those found in SARS-CoV-2. As such, exposure to these proteins may train our immune system to respond when it encounters the virus. The study paves the way for new immunotherapies or vaccines that lead to stronger immunity against Covid-19. SARS-CoV-2: comfort in the familiar? SARS-CoV-2 is new, and the pandemic can make it feel like an alien invader from another planet. However, it […]

Life sciences

22 Sep 2022

Teams of sperm swim more smoothly against the current

By Peter Rejcek, science writer The physics of how sperm navigate their way to an egg in mammals, including humans, are not well understood. The tendency for sperm to cluster together as they make their way upstream through the thickish, elastic-like fluid of the female reproductive tract is more than just random behavior. Researchers have found biological benefits for sperm working together that may have implications for fertility studies. It turns out sperm go against the flow better when they swim together. Despite the popular idea that the fastest and fittest male reproductive cell is the one that wins the fertilization race, research has shown that spermatozoa often team up to navigate the female reproductive tract in a wide range of mammalian species. A new study published in the journal Frontiers in Cell and Developmental Biology offers some compelling reasons behind a newly identified clustering behavior. Previous research by the team, led by scientists out of North Carolina A&T State University and Cornell University, first discovered that sperm naturally pull together without attaching to each other when swimming in viscoelastic fluid. This is the type of fluid encountered by sperm migrating through the cervix and uterus to the oviduct where […]

Life sciences

09 Sep 2022

Scientific ‘detective work’ reveals South American mummies were brutally murdered

By Mischa Dijkstra, Frontiers science writer Sketch from the book by Reiss and Stübel (1887. The necropolis at Ancon) on the excavations and findings at the necropolis of Ancon, Peru. As it was typical at the end of the 19th/beginning of the 20th century, the content of graves was examined on the spot: mummy bundles and objects worth selling were taken away, invaluable items discarded. An international team used interdisciplinary techniques including 3D CT to do a ‘virtual autopsy’ on three mummies found in Peru and Chile, dating to between 900 and 1300 CE. They show that both male mummies had been murdered. These results highlight the wealth of archeological information that can be gained from mummies, as opposed to from skeletons. How frequent was violence in prehistoric human societies? One way to measure this is to look for trauma in prehistoric human remains. For example, a recent review of pre-Columbian remains found evidence of trauma from violence in 21% of males. So far, most studies of this kind focused on skulls and other parts of the skeleton, but a potentially richer source of information are mummies, with their preserved soft tissues. Now in a new study in Frontiers in […]

Life sciences

30 Aug 2022

Beetles rely on unique ‘back pockets’ to keep bacterial symbionts safe during metamorphosis

By Mischa Dijkstra, Frontiers science writer Lagria villosa adult. Image credit: RS Janke Researchers show that beetles in the genus Lagria have evolved unique ‘back pockets’ on their larvae and pupae to house bacterial symbionts, which protect the immature life stages against fungi. But in adult females, the symbionts exclusively occur in the accessory glands, next to the oviduct, from where they are deposited onto eggs. When the adult beetles emerge, friction shuffles the symbionts out of the pockets and backwards to the genital area. They then colonize the accessory glands by an unknown mechanism. Beetles of the genus Lagria need a little help from their bacterial friends throughout their immature life stages. But keeping them in the same spot throughout life isn’t feasible. This is because beetles are holometabolous insects, which undergo an overall bodily reorganization (metamorphosis) as pupae. Here, scientists show for the first time that the beetles have evolved an ingenious solution to this problem: female pupae keep their symbiotic bacteria in specialized pockets on their back. When they emerge as adults, they shuffle the bacteria out of these pockets, backwards and then on into their genital area. These results are published in Frontiers in Physiology. ► Read […]

Life sciences

17 Aug 2022

Modern pesticides damage the brain of bees so they can’t move in a straight line

By Mischa Dijkstra, Frontiers science writer Image: Shutterstock.com Researchers show for the first time that honeybee foragers exposed to the pesticides sulfoxaflor and imidacloprid have an impaired optomotor response, which makes them poor at keeping themselves on a straight trajectory while moving. This impairment is accompanied by damage to brain cells and dysregulation of detoxification genes. These results add to the growing evidence that modern pesticides are highly damaging to beneficial insects like bees. The challenge to let people walk back and forth in a straight line isn’t just used by police to test if drivers are intoxicated: it’s also used by neurologists to diagnose neurological disorders like ataxia, where parts of the brain that coordinate movement are impaired. Now, researchers use an insect version of this challenge to show for the first time that modern pesticides damage the nervous system of honeybees so that it becomes hard for them to walk in a straight line. The results are published in Frontiers in Insect Science. “Here we show that commonly used insecticides like sulfoxaflor and the neonicotinoid imidacloprid can profoundly impair the visually guided behavior of honeybees. Our results are reason for concern because the ability of bees to respond […]