Health
20 Dec 2023
Researchers from China monitored 25 obese patients losing weight during and after intermittent energy restriction (IER) for changes in their gut bacteria and in brain regions for appetite and addiction. They showed that changes in both these compartments of the brain-gut-microbiome axis are tightly coupled in time.
Health
07 Dec 2023
New study shows that working night shifts favors development of sleep disorders, particularly in young adults with a lower education
Health
08 Nov 2023
by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Scientists have found that specially processed samples of willow bark extract have an antiviral effect which isn’t seen in already known medical compounds from willow bark, such as salicylic acid, the precursor to modern aspirin. The extract worked against two common types of virus with very different structures, enteroviruses and coronaviruses, suggesting the potential for a new broad-spectrum antiviral to help us fight viruses that are otherwise hard to treat. From a seasonal cold to a stomach bug, nobody likes catching a virus — and epidemics can be devastating. We need safe, sustainable antiviral options to treat the outbreaks of the future. Scientists in Finland have now shown that an extract of willow bark — a plant which has already provided several medicines, including the precursor to modern aspirin — has a broad-spectrum antiviral effect in cell sample experiments. The extract worked both on enveloped coronaviruses, which cause colds as well as Covid-19, and non-enveloped enteroviruses, which cause infections such as flu and meningitis. There are no clinically approved drugs which work against enteroviruses directly, so this extract could be a future game-changer. “We need broadly acting and efficient tools to combat […]
Health
07 Nov 2023
by Deborah Pirchner, Frontiers science writer Image: Shutterstock.com Fluctuations in sex hormones influence brain activity of the fear circuitry. A team of researchers in Canada has now examined the effects of oral contraceptive (OC) use on women’s brains. Their findings showed that ventromedial prefrontal cortex (vmPFC) thickness of women who were using OCs was reduced compared to men, suggesting a mechanism on how OC use could impair emotion regulation in women. Based on this study, this effect appears to be reversible after discontinuing use. More studies on impact and reversibility are needed, the researchers cautioned. More than 150 million women worldwide use oral contraceptives. Combined OCs (COCs), made up of synthetic hormones, are the most common type. Sex hormones are known to modulate the brain network involved in fear processes. Now a team of researchers in Canada has investigated current and lasting effects of COC use, as well as the role of body-produced and synthetic sex hormones on fear-related brain regions, the neural circuitry via which fear is processed in the brain. “In our study, we show that healthy women currently using COCs had a thinner ventromedial prefrontal cortex than men,” said Alexandra Brouillard, a researcher at Université du Québec […]
Health
01 Nov 2023
by Deborah Pirchner, Frontiers science writer Image: Shutterstock.com Many people experience stress, anxiety, and depressive symptoms in their life. Times of transition, such as pregnancy and children starting school can be significant periods of stress and vulnerability within families. Studies have generally found that high levels of anxiety and depression in parents are linked to poorer behavioral and cognitive outcomes in children. Now, a team of researchers in Canada has examined if self-reported paternal anxious and depressive symptoms are associated with children’s cognitive functioning and behavior. They found that slightly higher, but mild anxious or depressive symptoms in fathers were associated with fewer behavioral difficulties in the first years of elementary school and better scores on a standardized IQ testing in their children. The results need to be confirmed by further studies, the researchers said. While the role of mothers’ stress, anxiety and depression on children’s behavioral and cognitive development is well established, less is known about the connection between fathers’ mental health and children’s development. Now, a team of researchers affiliated to different institutions across Quebec, Canada has examined if paternal anxious and depressive symptoms, measured during their partner’s pregnancy, and again six to eight years later, are associated […]
Health
25 Oct 2023
by Deborah Pirchner, Frontiers science writer Image: Shutterstock.com Even before it was found to reduce pain and anxiety in modern times, music has been used for centuries to relieve pain. Now, researchers in Canada have investigated which aspects of listening to music can lead to a decreased pain perception. They found that participants’ perception of pain intensity and unpleasantness was reduced when they listened to their favorite music compared to pre-selected relaxing music, which is commonly used in clinical settings. In addition, bittersweet music – unlike other emotionally loaded music – was found to additionally reduce pain unpleasantness. Research has shown that music might be a drug-free way to lower humans’ pain perception. This decreased sensitivity to pain – also known as hypoalgesia – can occur when pain stimuli are disrupted between their point of input and where they are recognized as pain by the conscious mind. In a new study, researchers in Canada have examined what type of music helps to dampen pain perception. “In our study, we show that favorite music chosen by study participants has a much larger effect on acute thermal pain reduction than unfamiliar relaxing music” said Darius Valevicius, a doctoral student at the Université […]
Health
16 Oct 2023
by Deborah Pirchner, Frontiers science writer Image: Shutterstock.com At Frontiers, we bring some of the world’s best research to a global audience. But with tens of thousands of articles published each year, it’s impossible to cover all of them. Here are just five amazing papers you may have missed. Chronic pain associated with increased dementia risk Alzheimer’s disease and related dementias (ADRD) make up approximately 80% of the more than 47 million cases of dementia worldwide. Looking into the future, cases are expected to increase sharply in the coming decades. A large percentage of the older population is also affected by chronic pain, a leading cause of disability that shares many risk factors with ADRD. These include advanced age, depressive disorders, diabetes, obesity, social isolation, and a low level of education. Now, researchers in France have assessed the impact of chronic pain on the incidence of ADRD. They published their results in Frontiers in Aging Neuroscience. They found that the presence of chronic pain is associated with a higher incidence and risk of developing ADRD when compared with older adults with no chronic pain. The researchers stressed the importance of prevention, diagnosis, and management of chronic pain to limit resulting […]
Health
12 Oct 2023
by Deborah Pirchner, Frontiers science writer Image: Eric Arce for Outride Physical activity promotes mental well-being and finding activities that people are keen to engage in is key. For teenagers, cycling might be one of them – combining fun, competition, and transportation needs. Researchers in the US have examined if taking part in an in-school cycling program improves middle schoolers’ mental health and found positive effects. While they concluded that cycling programs may be a pathway to improved mental well-being of teenagers, they also noted that the conditions in which students are born and live in determine mental and physical well-being significantly. Physical activity has positive effects on mental health and yet, activity rates are declining. This is particularly worrying because the mental well-being of teenagers continues to deteriorate. In the US, one in six school children is diagnosed with some type of mental disorder. Riding bikes is a promising approach to introduce school-aged children to physical activity. Now, researchers in the US have investigated how adolescents’ psychosocial well-being changed after participating in a school-based cycling program. “Participation in a school cycling education program during the Covid-19 pandemic was associated with improved psychosocial well-being amongst middle schoolers in the US,” […]
Health
05 Oct 2023
by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Eating more plant-based dishes is good for your health and good for the planet – but the perception that these dishes are for women and not for men may be stopping some men from choosing plant-based meals. Scientists found that you can present vegan dishes with a masculine framing, altering the perception that these dishes are for women, but changing the perception doesn’t change people’s preferences. Eating more plant-based meals is better for our health and better for the planet. But cultural preferences are significant barriers to reducing meat consumption – especially for men, who are underrepresented among vegans and vegetarians. Studies have found that eating meat is associated with masculinity, and that gender stereotypes label plant-based diets as suitable for women but not men. So is it possible to change the perception of plant-based food with marketing, and convince men to eat more of it? “Men might be less inclined to consume vegan food due to the need to perform gender,” said Alma Scholz, lead author of a new study published in Frontiers in Communication. “However, with vegan food being framed in a masculine way, men might feel less resistance and […]
Health
27 Sep 2023
By Mischa Dijkstra, Frontiers science writer Researchers rated the teaching style of swimming teachers in the Netherlands, focusing on the degree to which the need for autonomy, competence, and relatedness of children were thwarted or supported on the whole. They concluded that there is an opportunity to improve swimming teaching styles, especially by focusing more on the need for autonomy in children. It is expected that this will improve the enjoyment of children and their willingness to continue once they have become competent swimmers. Learning to swim is not just potentially life-saving: it also provides a full-body workout that promotes cardiovascular and lung health. While in high-income countries most children learn to swim, few join a swimming club afterwards. Here, authors from the Netherlands showed that the way that swimming lessons are taught in the Netherlands can be improved. This could stimulate more children to keep up the activity. The results are published in Frontiers in Sports and Active Living. Lead author Carola Minkels, a doctoral student at the Department of Human Movement Sciences of the Free University Amsterdam, said: “Here we show that swimming lessons in the Netherlands poorly support the intrinsic motivation of children: their need for autonomy […]
Health
13 Sep 2023
By Mischa Dijkstra, Frontiers science writer Researchers have shown that high concentrations of key proteins in human breast milk, especially osteopontin and κ-casein, are associated with a greater abundance of two species of bacteria in the gut of babies: Clostridium butyricum and Parabacteroides distasonis, known to be beneficial for human health and used as probiotics. These results suggest that proteins in breast milk influence the abundance of beneficial gut microbes in infants, playing an important role in early immune and metabolic development More than 320 million years of mammalian evolution has adapted breast milk to meet all the physiological needs of babies: it contains not only nutrients, but also hormones, antimicrobials, digestive enzymes, and growth factors. Furthermore, many of the proteins in breast milk, for example casein and milk fat globule membrane proteins, aren’t just sources of energy and molecular building blocks, but also directly stimulate immunity, at least under preclinical conditions. Likewise, the gut microbiome, composed of bacteria, archaea, and fungi, plays a vital role in the regulation of the immune system. This raises the possibility that the immune-boosting function of breast milk proteins might be two-pronged: not only by stimulating the immune system directly, but also indirectly, by […]
Health
07 Sep 2023
by Dr Dario Novak, University of Zagreb Image courtesy of Dr Novak: Dario Novak and Marin Čilić, 2020 Olympic silver medalist To provide adequate support to young athletes, it is important to understand their development path. Over the years, researchers have recognized the significance of tracking all processes aimed at optimizing athletes’ progress and overall success. In a new study by Mario Oršolić, Dr Petar Barbaros, and Dr Dario Novak, 30 tennis players at different levels of success were interviewed, including 10 Grand Slam winners, to understand how they got into the sport and what drove their success. The research, published in Frontiers in Sports and Active Living, sought to deepen the understanding of specialization in tennis by exploring the experiences of tennis players at different levels of success. By analyzing their stories, the researchers aimed to contribute to a wider knowledge on the development of tennis players, as well as providing valuable insight for individual sports careers. They condensed their findings down to the following guidelines for coaches and players: It is important that the initial introduction into tennis for younger children is aimed at stimulating positive feelings and love for the sport; Specialization (targeted and more intensive training) […]
Health
31 Aug 2023
by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Maintaining a regimen of antipsychotic drugs can be difficult, but going off them unexpectedly can have disastrous health consequences for patients. Traditionally, monitoring patients on these drugs involves blood tests, which can be painful and time-consuming. A quick, non-invasive finger sweat test newly developed by scientists could replace these blood tests and make patients’ lives easier. Antipsychotic drugs treat incredibly vulnerable patients. Maintaining a treatment regimen is difficult for many patients, but not taking the medication is associated with a higher risk of poor health outcomes. These drugs are also very powerful with strong side-effects, and blood tests are often used to calibrate a patient’s dosage and confirm that they are taking the recommended dose. However, blood tests are invasive and potentially uncomfortable. Scientists have now discovered a way to test the levels of common antipsychotic drugs in the sweat from patients’ fingerprints, offering a quicker, more comfortable, and more convenient alternative to blood draws for patient monitoring. “Our test offers patients a quick and dignified way of showing commitment to antipsychotic treatment,” said Katherine Longman of the University of Surrey, first author of the study in Frontiers in Chemistry. “This non-invasive […]
Health
24 Aug 2023
by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Scientists have developed a device that works with a smartphone or tablet to capture medical images which can identify infected wounds. By capturing the heat produced by a wound and the fluorescence of bacteria, it helps clinicians tell the difference between inflammation and a potentially dangerous infection. This could allow for quicker intervention, catching infections before they become serious threats to health. It’s notoriously difficult for doctors to identify a wound that is becoming infected. Clinical signs and symptoms are imprecise and methods of identifying bacteria can be time-consuming and inaccessible, so a diagnosis can be subjective and dependent on clinician experience. But infection can stall healing or spread into the body if it isn’t treated quickly, putting a patient’s health in grave danger. An international team of scientists and clinicians thinks they have the solution: a device run from a smartphone or tablet app which allows advanced imaging of a wound to identify infection. “Wound care is one of today’s most expensive and overlooked threats to patientsand our overall healthcare system,” said Robert Fraser of Western University and Swift Medical Inc, corresponding author of the study published in Frontiers in Medicine. […]
Health
23 Aug 2023
By Mischa Dijkstra, Frontiers science writer Researchers analyzed health information on middle-aged and senior participants in the UK Biobank. They showed that those who took part in adult education classes had a 19% lower risk of developing dementia within five years of follow-up. Adult education also appeared to help preserve nonverbal reasoning performance and fluid intelligence. How can we best keep our brain fit as we grow older? It’s well known that regular cognitive activity, for example brainteasers, sudokus, or certain video games in middle and old age tends to protect against cognitive decline and dementias like Alzheimer’s. But many of us regularly engage in adult education classes, for example learning a language or a new skill. Is such adult education likewise associated with a lower risk of cognitive decline and dementia? Yes, according to researchers from the Institute of Development, Aging and Cancer of Tohoku University in Sendai, Japan who have shown this for the first time, in a new study in Frontiers in Aging Neuroscience. “Here we show that people who take adult education classes have a lower risk of developing dementia five years later,” said Dr Hikaru Takeuchi, an associate professor and the study’s first […]
Get the latest research updates, subscribe to our newsletter