
Health
01 Feb 2016
VIDEO: Scientist’s work plays leading role in redefining our understanding of the brain’s systems
By Ben Stockton With a wish to not appear immodest, Professor Pierre Magistretti tentatively indicates two moments that have shaped his career. The first came with the surprise that lactate, more typically associated with insufficient blood supply to muscle, was being produced by the support cells of the brain, known as glia or astrocytes, and used as an energy source for neurons. “Neurons can send messages to glial cells and tell them, “please get us some energy,”” and this arrives in the form of lactate, explains Magistretti. It recently became apparent that lactate had further implications in the brain. Magistretti and his peers are now “fully engaged in understanding how this lactate is not only an energy substrate but also a signal for plasticity and memory,” which has become a cornerstone of his current work. Magistretti, a Professor at the King Abdullah University of Science and Technology in Saudi Arabia and at the Brain Mind Institute at EPFL in Lausanne, could be excused for immodesty. His contribution to the field of brain energy metabolism have seen him awarded with the IPSEN Neuronal Plasticity prize and he currently presides over the International Brain Research Organization. Amongst this, he lends his expertise […]