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MINI REVIEW article

Front. Syst. Biol.
Sec. Integrative Genetics and Genomics
Volume 4 - 2024 | doi: 10.3389/fsysb.2024.1497510

Interplay of Circular RNAs in Gastric Cancer -A Systematic Review

Provisionally accepted
Dipanjan Guha Dipanjan Guha Jit Mondal Jit Mondal Anirban Nandy Anirban Nandy Sima Biswas Sima Biswas Angshuman Bagchi Angshuman Bagchi *
  • University of Kalyani, Kalyani, India

The final, formatted version of the article will be published soon.

    Circular RNAs (circRNAs) have gained prominence as important players in various biological processes such as gastric cancer (GC). Identification of several dysregulated circRNAs may serve as biomarkers for early diagnosis or as novel therapeutic targets. Predictive models can suggest potential new interactions and regulatory roles of circRNAs in GCs. Experimental validations of key interactions are being performed using in vitro models, confirming the significance of identified circRNA networks. The aim of this review is to highlight the important circRNAs associated with GC. On top of that an overview of the mechanistic details of the biogenesis and functionalities of the circRNAs are also presented. Furthermore, the potentialities of the circRNAs in the field of new drug discovery are deciphered.

    Keywords: circRNA, Biogenesis, gastric cancer, early diagnosis, Therapeutics

    Received: 17 Sep 2024; Accepted: 31 Oct 2024.

    Copyright: © 2024 Guha, Mondal, Nandy, Biswas and Bagchi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Angshuman Bagchi, University of Kalyani, Kalyani, India

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