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ORIGINAL RESEARCH article

Front. Robot. AI, 16 October 2024
Sec. Bio-Inspired Robotics
This article is part of the Research Topic Latest Trends in Bio-Inspired Medical Robotics: Structural Design, Manufacturing, Sensing, Actuation and Control View all 7 articles

Novel bio-inspired soft actuators for upper-limb exoskeletons: design, fabrication and feasibility study

Updated
  • Mechanical Engineering, The University of Texas at Austin, Austin, TX, United States

Soft robots have been increasingly utilized as sophisticated tools in physical rehabilitation, particularly for assisting patients with neuromotor impairments. However, many soft robotics for rehabilitation applications are characterized by limitations such as slow response times, restricted range of motion, and low output force. There are also limited studies on the precise position and force control of wearable soft actuators. Furthermore, not many studies articulate how bellow-structured actuator designs quantitatively contribute to the robots’ capability. This study introduces a paradigm of upper limb soft actuator design. This paradigm comprises two actuators: the Lobster-Inspired Silicone Pneumatic Robot (LISPER) for the elbow and the Scallop-Shaped Pneumatic Robot (SCASPER) for the shoulder. LISPER is characterized by higher bandwidth, increased output force/torque, and high linearity. SCASPER is characterized by high output force/torque and simplified fabrication processes. Comprehensive analytical models that describe the relationship between pressure, bending angles, and output force for both actuators were presented so the geometric configuration of the actuators can be set to modify the range of motion and output forces. The preliminary test on a dummy arm is conducted to test the capability of the actuators.

1 Introduction

Soft robotics, in contrast to traditional rigid robots, are often considered safer for human-robot interaction due to their inherent compliant properties. This characteristic is particularly crucial for rehabilitation applications (O’Neill et al., 2017; Fang et al., 2020). Soft robots also exhibit a high power-to-weight ratio (O’Neill et al., 2022) and are typically lighter than rigid exoskeletons, which may enable soft actuator-based exoskeletons to operate in a more power-efficient manner.

This lightweight nature, combined with the inherent flexibility of soft materials, enhances the wearability and comfort of wearable exoskeleton devices. The improved wearability not only reduces user fatigue but also increases mobility, making these devices easier to transport and wear for extended periods. Consequently, soft wearable robots are well-suited for use in daily living environments, supporting rehabilitation and assistance in a more practical and user-friendly way. Additionally, developing soft robots is generally more cost-effective compared to manufacturing most rigid exoskeletons.

In rehabilitation training, there are two categories of soft robots commonly implemented tendon-driven and pneumatic-driven. Tendon-driven exosuits use strings and ropes as transmission and soft materials as interfaces between human tissue and the end effect point of the transmission. These systems can achieve a large range of motion, precise force, and position control, and generate large output force/torques Yun et al. (2017b), Yun et al. (2020), Yun et al. (2017a). However, several issues originate from tendon-driven soft exoskeletons. The strings connecting the tendon-driven actuators to the motors are prone to stretching, which requires them to be housed in isolated spaces to prevent unintended contact with the surrounding environment Yun et al. (2017a). Furthermore, the movement of a person’s limbs can also shift the position of the strings’ ends, leading to unwanted slack or tension in the strings. Tendon-driven joints also need at least two strands of strings to realize bidirectional motion with only one pipe given the elastic (or hyper-elastic) property of the actuator body (Gerez et al., 2019).

Pneumatically driven soft actuators are commonly used in human-involved experiments due to their intrinsic compliance and easy setting-up process. Heung et al. (2019) developed a silicone rubber-based beam-shaped wearable glove to assist with post-stroke rehabilitation training. Similarly, Park et al. (2022) introduced a fabric-based pneumatic exoskeleton for elbow-assistive motion. Natividad and Yeow (2016) introduced an inflatable, fabric beam shoulder actuator emphasizing lightweight and simple structural design. However, this design result is bulky and has limited output force. An extension from Natividad et al. (2021) introduces another design aiming to cover both the shoulder and elbow with a single mechanism. This design occupies substantial volume and requires numerous pneumatic actuator modules, making fabrication complex and cumbersome. There are other previous pneumatically-driven soft robotic systems for upper-limb assistive training. In general, these actuator designs, despite being suitable intrinsically for rehabilitation training, show limitations in assistive motion tasks including:

(1) Insufficient moment of force to effectively support human limb motion. The typical range of force generated by silicone rubber-based soft robots is from 0–10 N (Huang et al., 2020), less than the required force to push the human’s upper limb.

(2) The fabrication process for soft robotics is time-consuming and requires complicated tools. Many fabrications, especially the fabrication of inextensible fabric-based devices, require laser cutting and heat-sealing machines (Nguyen et al., 2019; Natividad et al., 2021).

(3) Establishing an accurate analytical model for soft robots is difficult due to the highly nonlinear property of the hyper-elastic material and the challenge of describing their irregular shape in analytical forms (Müller et al., 2020; Huang et al., 2020; Natividad and Yeow, 2016).

In this study, we introduce a design paradigm of soft pneumatic actuators for upper-limb assistance comprised of two soft actuator designs Lobster-Inspired Silicone Pneumatic Robot (LISPER) for below shown in Figure 1A SCAllop-Shaped Pneumatic Robot (SCASPER) Figure 1B along with their analytical modeling to tackle the issues mentioned above. Lobster-Inspired Silicone Pneumatic Robot (LISPER) is inspired by the rigid crust of the lobster and from which we included the c-shape constraint to restrict the elongation of the outer rings of LISPER as shown in Figure 1A. Similarly, the Scallop-Shaped Pneumatic Robot (SCASPER) is inspired by the opening motion of scallops. When the adductor muscle of the SCASPER inflates, then the two fans of the scallop open (Figure 1B). The model not only describes the relationship between pressure, bending angles, and output force but also explains how to change the range of motion and output forces numerically by modifying the geometry of the bellows. The feasibility of the device is tested on a dummy arm by applying position and gravity compensation controls.

Figure 1
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Figure 1. (A) Experimental Platform of LISPER for Unloading Bending Test (B) Experimental Platform of SCASPER for Unloading Bending Test (C) 2-DOF dummy arm before inflation. (D) 2-DOF dummy arm after inflation.

In specific, this research makes contributions in three aspects:

(1) In mechanical design, we propose two types of pneumatic-driven soft actuators, Scallop-Shaped Pneumatic Robot (SCASPER) and Lobster-Inspired Silicone Pneumatic Robot (LISPER) for the shoulder and elbow, respectively. Both actuators outperform previous works in dynamic properties, including range of motion, maximum force output, linearity between pressure input and position output, low hysteresis, and high bandwidth, as mentioned above and in Table 1.

(2) In analytical modeling, we characterize the contribution of unfolding bellow structure by analytical modeling. This model can be used for parameter-driven mechanical design as it demonstrates how the triangular bellows design significantly enhances performance, providing additional forces and increased bending angles in response to pressure input.

(3) In the fabrication method, we introduce a concise fabrication technique to make inextensible soft actuators (SCASPER) that do not require fabrication machines and are time-efficient. Besides, we elaborate on the fabrication techniques to avoid failures caused by stress concentration and air leakage, which are common in large soft actuators.

Table 1
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Table 1. Comparison between designed actuators with other state-of-the-art works. Panel A Comparison between LISPER and the state of the art. Panel B Comparison between SCASPER and the state of the art.

Among the two actuators, LISPER is designed with 1) precise bending motion without a sophisticated controller, 2) high linearity between bending angle and inflation pressure input, 3) higher bandwidth and faster response rate, and 4) the ability to generate larger force and moment of force than conventional pneumatic soft robots.

However, the output force from the LISPER is insufficient to support motions of shoulder. The other actuator, SCASPER, is designed to solve this issue. Its features include 1) the ability to generate large output force/torques to support heavy human arms, 2) adjustable linearity and quicker deflation speed than conventional soft robots made of inextensible layers, and 3) low difficulty of fabrication and requiring only commonly used materials (e.g., polyethylene heat-shrinking tubes).

The research community could benefit from this work in two aspects 1) By directly following the design and fabrication process, rehabilitation studies could use the design for clinical research. 2) Upgrade upper-limb exoskeleton can be made following the design paradigm including c-shape constraints, tunable elasticity from rubber strips, two-actuator frame for the two joints, and parameter-driven geometric design.

The following sections are as follows:

Section 2 elaborates on the mechanical design and fabrication of LISPER and SCASPER. This section also explains the simulation of two actuators with the finite element analysis method (FEA/FEM) and the comparison with experimental results. Section 3 introduces the analytical modeling of LISPER and SCASPER, and discusses the impact of the bellow structure and its quantitative contribution to the range of motion and output force. Section 4 introduces how the experiments are conducted and compares the results with simulations. Section 5 discusses the details and limitations of the current work and explains prospective work. Finally, Section 6 summarizes the conclusion.

2 Mechanical design and fabrication

2.1 Design considerations

The main purpose of the mechatronic design is to provide dynamic gravitational compensation for human subjects along upper-limb rehabilitation training procedures. Therefore, the metrics of the wearable design include 1) Large range of motion, 2) Significant assistive force, 3) High Response rate 4) Comfortable wearability.

To alleviate the difficulty of the fabrication process, the SCASPER is designed to be manufactured without machine tools. The main structure of the SCASPER shall be made of material low-cost and easy to obtain. The main configuration of LISPER and SCASPER are listed in Tables 2, 3. The size of the LISPER and SCASPER is defined by measuring the width of an adult male’s forearm and rear arm, which are around 70 mm and 100 mm respectively. The actuators are designed to be around 10%–20% shorter than these widths. This dimension setting aims to avoid bulkiness while providing sufficient output force/torque.

Table 2
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Table 2. Main Configuration of LISPER.

Table 3
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Table 3. Main Configuration of SCASPER.

2.2 Mechanical design: Lobster-Inspired Silicone Pneumatic Robot (LISPER)

LISPER (Figures 2A–D), drawing design inspiration from the morphology of lobster fins, is designed for motor joints like elbows and wrists that necessitate low output force/torque for operation, particularly in scenarios where gravitational force compensation is minimal. In a coordinated system, LISPER has the potential to collaborate with SCASPER to facilitate precise horizontal rotational movements, with SCASPER primarily addressing the substantial components of gravitational force. With these in mind, the design objectives established for LISPER included 1) achieving high linearity between applied pressure and bending angle in unloaded conditions and 2) ensuring a high response rate.

Figure 2
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Figure 2. (A, B) Actual and CAD designs of LISPER. (C) Demonstration of components of unassembled LISPER and (D) The side view of LISPER. (E) Exploded view of molding and casting procedure of LISPER. (F, G) CAD demonstration of SCASPER, θ is the extension angle. (H, I) are front and rear views of actual SCASPER.

To achieve the design objectives, an arc-shaped body and bellows with sharp folds on one side of the external surface and the internal surface of the air chamber were incorporated into LISPER. These features serve several purposes: The arc-shaped design combined with bellow-shaped folds enables pure bending motion without undesired elongation, commonly occurring along the actuator’s length. The sharp bellows tend to unfold under uniform pressure applied to the chamber’s internally folded surface. Bellow-shaped folds on the internal surface reduce the air chamber’s volume, decreasing inflation and deflation times and reducing response time. The unfolding process of the bellow-shaped surface also accelerates bending speed. A minor benefit of an arc-shaped design is that it shifts the contact area between human tissue and the soft robot from the bottom to the side of the actuator, avoiding uncontrollable friction and the contact area between the surfaces. This change helps reduce sliding between surfaces, minimizing energy dissipation.

In addition to the bellow and arc shape design, rigid-soft coupling was employed to constrain undesired radial extension and “inverse folding” of the bellow-shaped folds. Brace locker and C-shape braces were added to the external edges of each fold, and a fabric mesh with hexagon patterns was placed between the brace and each fold’s tips (Figure 2B). When stretched in one direction, the hexagon fabric mesh shrinks in the perpendicular direction. This property achieves two goals: 1) providing an upper folding boundary to prevent inverse folding and 2) further decreasing undesired radial extension. A U-shaped 3D-printed TPU layer was added around the actuator’s bottom to constrain elongation in that area and define the bending’s neutral layer (Figure 2E). The actuator’s two “feet” were sealed with flat PLA plates.

The features introduced in LISPER’s design, including the C-shaped braces and the meshes, are mainly designed to constrain the undesired radial elongation of the silicone rubber’s chamber and consequently increase the response rate. The bellow structure helps realize high linearity between input pressure and bending angles or output forces. It also provides a higher range of motion and output forces. The quantitative details will be in the analytical modeling section of LISPER.

2.3 Mechanical design: Scallop-shaped Pneumatic Robot (SCASPER)

SCASPER (Figures 2F–I), inspired by scallop fan shells, was designed to generate a large output force/torque and high linearity bi-directional motion. SCASPER is classified as an inextensible airbag pneumatic actuator, which usually generates larger moments of force (2 to 15 Nm) than silicone rubber-based soft robots like LISPER. However, conventional air-bag-based actuators predominantly suffer from (1) low linearity between inflation pressure and bending angles, (2) slow deflation speed, (3) severe hysteresis for bi-directional translation, and 4) complicated fabrication processes. These issues were considered in the development of SCASPER.

The design of SCASPER features a rotationally patterned arrangement of rectangular airbags, with two external corners trimmed off. This modification brings the contact points of the bags closer to the rotational axis, thereby enhancing the extension angle θ (Figure 2F). To speed up deflation and enhance the linearity between pressure and angle, silicone rubber strips were added to connect the external edges of the airbag (Figure 2I). These strips facilitate SCASPER’s tendency to return to its original position. A notable feature of SCASPER’s mechanical design is its construction from polyethylene heat-shrinking tubes, eliminating the need for layer stacking. The tube material does not impact performance because the angular extension does not rely on bag elasticity. Furthermore, this design allows for individual airbag airtightness checks before assembly into the overall structure.

2.4 Finite element analysis of LISPER and SCASPER

In this section, we discuss the application of FEA to simulate the relationship between inflation air pressures and corresponding bending angles for LISPER and SCASPER, considering their complex geometric structures. The simulation serves three primary purposes: (1) to provide proof of concept regarding bending direction, expected deformation, the linearity between air pressure and bending angles, and the output force/torque in different angular constraints; (2) to enable comparison between simulation results and experimental data; and (3) to identify stress concentration areas that could be potential sources of significant air leakage.

For the free motion of the simulation for LISPER, we assumed that the brace lockers and C-shape braces have large stiffness and do not deform during simulation by applying an elasticity of 4.4 MPa and Poisson’s ratio of 0.22 based on the experiment conducted by Wang et al. (2019). The mesh introduced in Section 2 is excluded from the simulation, as the inverse folding does not occur in the unloading state. A curved 2D plane was added at the middle plane of the TPU to represent the neutral layer. The Yeoh model was chosen for its simplicity and minimal parameter requirements in describing the hyper-elastic model. A general static model was used, as the inflation can be considered a quasi-static process. The inflation pressure was applied uniformly inside the internal chamber, increasing linearly from 0 kPa to 100 kPa in increments of 5 kPa (Figure 3). The simulated relationship between pressure and angles, along with a comparison with the experimental results, is shown in Figure 4A.

Figure 3
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Figure 3. FEM simulation of the stress distribution of LISPER with a pressure range from 10 kPa to 65 kPA. Note: The c-shaped brace is hidden on the image for clear demonstration.

Figure 4
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Figure 4. (A, D) Comparison between modelings and experimental bending angle for LISPER and SCASPER, respectively. (B, E) Comparison between analytical model-based prediction, FEA, and experiment on Pressure vs. Force and Pressure vs. Torque of LISPER and SCASPER under different fixed angles. (C, F) Comparison between the PID model-free controller and the model-based position controller applied to the elbow and shoulder, respectively.

The free motion of the simulation of SCASPER is based on the assumption that the material used for the airbag is inextensible. We set the young’s modulus as 6.5 MPa and Poisson’s ratio to 0.02. These values were not obtained through rigorous experimentation, as the simulation results are not significantly affected by the elasticity properties of the airbag itself (Figure 5). Here, we applied dynamic explicit simulation. To determine the moment when all airbags attach, we applied the set pressure as a step input and allow the simulation to run for a sufficient amount of time. The simulated extension angles tend to oscillate in a sine wave pattern, from which we found the mean value (the offset of the sine wave) and defined it as the extension angle in a stable state. From Figure 5, it is evident that the high stress is primarily distributed around the two side surfaces of the airbags, which explains the choice of a shrinking tube instead of two separate fabrics for the airbag construction. The simulated relationship between pressure and angles is shown in Figure 4B, along with a comparison with the experimental result.

Figure 5
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Figure 5. FEM simulation of stress distribution of SCASPER with pressure range from 10 kPa to 90 kPa.

We also verified the impact of the C-shaped braces and brace locker rings, which were added to the external edges of each fold. Through FEA analysis, we found that the C-shaped braces and brace locker rings increased the bending angle by 22.5 at 60 kPa Figures 6, 7.

Figure 6
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Figure 6. The comparison in the simulation of LISPER with and without c-shaped braces.

Figure 7
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Figure 7. The comparison of LISPER actuator with or without braces at 65 kPa pressure input. (A) is LISPER without braces and (B) is with braces.

To estimate the output force/torques in certain angles, we fixed multiple flat plains to constrain the motion of the LISPER and SCASPER in 0, 45, and 60°deg. and adding the input pressure from 0 kPa to 100 kPa. The normal reaction forces from the plains are defined as the output forces/torques from the actuators. The simulation result is shown in Figures 4B, E.

2.5 Fabrication and assembly of LISPER

LISPER features a silicone rubber body made of Tin cure silicone rubber. After comparing Shore A hardness levels 10, 20, and 40, 20A (Smooth-on Mold Max 20) was chosen for its ability to facilitate smooth bending with moderate pressure variation in both bending and extending directions. LISPER’s construction included C-shaped braces and corresponding locker rings, two 3D printed PLA bottom plates (Polymaker PLA Filament) sealing the internal chamber ends, and an air inlet attached to one of the plates. The inlet hole was connected to a PU tube (Beduan Pneumatic Air Tubing Pipe) with epoxy (J-B Weld Pro Size ClearWeld 5 Minute Set Epoxy). Each brace housed four squared holes for positioning fabric meshes (50″ 8600 Polyester Dive Mesh, Seattle Fabric Inc.). The fabric mesh layers were placed between the braces and the silicone rubber body. Fixtures for the mesh utilized a series of C-shaped small arc pieces that grip the bellows’ edge and one side of the mesh hexagon. The silicone body features 15 bellows, which necessitated 15 pairs of C-shaped braces and locker rings.

A two-mold casting technique was employed to fabricate LISPER’s silicone rubber body (Figure 2E). A primary fabrication challenge was ensuring the high-viscosity liquid silicone rubber mixture uniformly fills the entire mold’s empty space. Failed castings are often a result of pores concentrated on the thin walls of the silicone rubber body. Therefore, syringe injection is unsuitable for filling the molds with silicone, as the high-viscosity liquid mixture may initially fill spaces with lower flow resistance, trapping air in small spaces and causing severe pores across the silicone rubber body. To address this issue, we utilized a vacuum pump and then decreased the temperature during the curing process. Additionally, we introduced air vent patterns, material inlet patterns, and a 3D-printed funnel to effectively prevent the accumulation of pores. The degassed silicone rubber liquid was poured into the funnel after being cooled with ice water. Positioned on the material inlet pattern atop the upper mold, the funnel allowed the liquid to flow slowly to the bottom of the empty space, pushing air upward to the air vent pattern locations.

In the molds used to fabricate LISPER, the two cores within the molds created a hollow chamber inside the silicone rubber body (Figure 2E). As detailed in the mechanical design section, one side of the silicone rubber body’s internal surface features a bellow-shaped structure, which was achieved by utilizing bellow-shaped cores. Each core contained two rectangular plugs corresponding to two grooves on the molds, ensuring accurate core-mold positioning and preventing downward core bias due to gravity.

A 3D-printed TPU layer (OVERTURE TPU Filament) was inserted around the mold’s bottom, which was wrapped with silicone rubber post-casting and embedded into the silicone rubber body. The holes on the TPU layer’s surface improved silicone rubber and TPU adhesion.

The chamber sealing process involved attaching two 3D-printed plates to the actuator’s ends. Additional freshly mixed silicone rubber was then added to the chamber ends. This was done by orienting the actuator upward and placing the SIL-Poxy coated plates (SIL-Poxy-Silicone Rubber Adhesive, Smooth-on Inc.) horizontally on both ends. The newly added silicone rubber mixture was then applied, and once it cured, it effectively sealed the chamber and firmly attached to the rest of the silicone rubber body.

2.6 Fabrication and assembly of SCASPER

The inextensible membrane-based SCASPER is composed of six airbags stacked together, maintaining a controlled distance between each one. Each airbag was crafted from a polyethylene heat-shrinking tube (ELECFUN 2in Heat Shrink Tubing), chosen for its compliance, wear resistance, accessibility, and affordability. The heat-shrinking tube’s sides were pre-sealed, reducing the likelihood of air leakage. The entire heat shrink tubing was divided into six equal-length pieces, with 5-hole and 6-hole patterns drilled on the distal (furthest from the rotational axis) and proximal (closest to the rotational axis) sides of the actuator to fix the bolts and nuts. Two corners on the distal side of each airbag were removed to bring the contact points between each airbag closer to the rotational axis of the SCASPER. The inlet was connected via a PU tube, and four long, flat ABS plates were used to seal the distal and proximal sides and secure the PU tube Figure 2H.

The six airbags were aligned and stacked on top of each other using pipe positioning rings. The six inlet pipes were merged into one to connect to the solenoid valve. Silicone rubber strips (Smooth-On Ecoflex 00-20 Super Soft Silicone) were connected at the distal end of each airbag (Figure 2I), which enables the adjustability of SCASPER.

The fabrication process of SCASPER takes approximately 45 min, excluding individual airbag airtightness testing. Overall, the fabrication procedure is significantly simplified, not requiring laser cutters, sewing machines, or heat-sealing machines. Given the strong adhesion of polyethylene heat-shrinking tubes to most types of tapes, achieving airtightness is relatively easy. SCASPER can withstand 150 kPa pressure input without experiencing irreversible deformation or significant air leakage.

3 Analytical modeling of LISPER and SCASPER

This section introduces the mathematical deduction process of the analytical models of LISPER and SCASPER. In these models, we use the general form of F=f(P,θ), where F is the output force for the actuator, P is the inflected pressure, and θ is the bending angle. The focus of the modeling section will be on explaining the inflation process of the bellow structure. The verification of the two analytical models is elaborated in the Mechatronic System for Experiments subsection in the Experiments and Results section, where we compare the models to experimental results.

3.1 LISPER analytical model: the modeling of the unfolding process of the bellow structure

The analysis of the unfolding process of LISPER is decomposed into three sections of the geometry of the soft robot structure: (1) the bellow structure, (2) the two bottom areas of the silicone rubber body, and (3) the arc structure.

Figure 8 describes the diagrams complementing the following modeling. Figures 8A–B show the common parts that will be mentioned throughout.

Figure 8
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Figure 8. Geometric diagram of LISPER. (A) The sectional view of the silicone rubber body. The outer ring section is constrained by PLA rings, the inner ring is the smallest contour of each bellow segment. (A1) The zoomed-in view of three pieces of bellow segments. (B) The labeling of three sections of small ring, arc, wall, and base. (C) Dimension labeling of the inner ring before inflation. (D) Dimension labeling of the inner ring after inflation. (F) Equivalent center of gravity and equivalent moment of arm. (G) Side view of the base section when it is bent.

The modeling process is formed based on several assumptions: 1) the linearization of hyper-elastic materials, which is based on the observation that the strain on the silicone rubber body is small; 2) the outer contour of the bellow segment does not extend given the PLA ring constraint of its outward motion; 3) the silicone rubber section between point A and point B in Figure 8A1 is straight, based on experimental observation.

From Marechal et al. (2021) which provides raw data for commonly used silicone rubber materials, we observe that when the range of strain is from 0 to 1, the stress-strain curve shows a high linearity, where Young’s modulus could be approximated by Equation 1:

E=σ/ϵ=1.53MPa(1)

where E is Young’s modulus of the silicone rubber body, σ is uniaxial stress, and ϵ is the strain of silicone rubber.

Using the Young’s modulus obtained, we investigate the mechanical behavior of LISPER during inflation. Figure 8C shows a cross-sectional cut of one of the bellows of LISPER, where.

θ3 - angle between the base of the bellow and the wall

R2 - radius from the center of the bellow to the external ring

h - height from the lower area of the base to the upper area of the base

2β - angle of the ring of the bellow (constant value of initial position)

dθ - differential angle of the ring of the bellow

lbase - length of the base

s - arc length

Once the air pressure is increased, the arc elongates following the Poisson effect. The resulting differential arc length, dsnew, of the bellow during inflation can be expressed as:

dsnew=dsinitial+dselongated=rdθ+rPlthickdθEv(2)

Since dsinitial=rdθ and dselongated=rPΔrdθEv

P - pressure during inflation.

r - radius of the middle layer between the inner ring and outer ring expressed as r=rinner+router2lthick - wall thickness of the whole small ring.

dsinitial - initial arc length, dsinitial=rdθdselongated - increase in arc length.

v - Poisson’s ratio

In application, we usually assume the Poisson’s ratio of silicone rubber to be around 0.5. In our practice, we found slight variations of Poisson’s ratio do not cause a visible impact on the numerical results.

Integrating Equation 2 from β to β, we can find the elongated arc length of the bellow during inflation, snew

snew=ββr+rnewPlthickEvdθ=r+rnewPlthickEv2β(3)

where rnew is the new radius of the middle layer during inflation. Assuming that βnewβ, we can have:

snew=rnew2β(4)

By substituting Equation 4 into Equation 3, this leads us to finding the new arc length:

snew=2βr+snewlthickPEv=2βr1lthickPEv(5)

To characterize the elongation of the side wall, consider Figure 8B, which shows the pressure profile along the wall. The elongation of the side wall can be found through:

lwall_new=lwall_initial+lwall_initiallthickPEv(6)

lwall_initial - length of the wall before elongation

lwall_new - length of the wall after elongation

Since we know snew from Equation 5, lwall_new from Equation 6, and l_base is a constant, we can find θ2,θ3 and rnew by simultaneously solving Equation 7 using a numerical solver and with the help of auxiliary lines along the plane of the bellow’s structure, as shown in Figure 8D:

θ22=θ3θ2=lnewrnewlbase2cosθ3=lwall_new+rnewtanθ22(7)

After acquiring all the geometric parameters, we can find the height of the sectional contour of the chamber, h(x) in Equation 8:

hx=tanθ3xlbase2lbase2<x<lbase+lwall_newcosθ3sinθ3lwall_newrnewcosθ22+rnew2x2|x|<lbasesnewcosθ3tanθ3xlbase2lbaselwall_newcosθ3<x<lbase2(8)

Now, we will characterize the forces generated by LISPER. To find the forces at the side spike of each bellow, we refer to (Figure 8E). First, we need to characterize the lateral compression of the below in Equation 9:

F2D=AΔlEA=dBellow_wall+ΔlvΔl=lnew lold (9)

where F2D is the force generated by the compression of each bellow segment in 2D, dBellow_wall is the width of the bellow wall, and Δl is the compressed length of bellow segment.

Applying cosine law, we can find Equation 10:

lold 2=OA2+OB22cosαOAOBlnew 2=OA2+OB22cosαOAOBOA=h2+hx(10)

where α is the angle between two extension side line intercepting at rotational axis O, α=θBending_angle/(2N).

From the equations above, we can find F2D(x), and by integrating from lbase2 to lbase2, we can find the compression force of the entire bellow structure, F3D in Equation 11:

F3D=lbase/2lbase/2F2Ddx(11)

To find the force generated at the side normal to the segment line of the bellow, Ftotal_1 (Figure 8A1), we can use Equation 12:

Ftotal_1=Ttotal_1lequiv=li×F3D,ilequiv=F3Dlcos90°γ2Nlequiv(12)

γ - angle between extension line of the tip of the bellow and the bellow’s segment

N - number of bellows

lequiv - length of the equivalent force’s executing point to the axis of rotation.

li - moment arm from the axis of rotation to the bellow

Now we need to find Ftotal 2, as shown in Figure 8A. Ftotal 2 is the force generated by the air pressure at the feet of the LISPER (Figure 8F) in Equation 13.

Ftotal_2=AfeetP(13)

Afeet - Area of the feet of the actuator

Now, we need to find the opposite force generated by the inner arc during the expansion of the actuator, Ftotal_3 (Figure 8G) with Equation 14:

Ftotal_3=ΔϕAbaseER(14)

Δϕ - difference of bending angle

Δϕ=θBending_angleθInitial_Bending_AngleAbase - sectional area of the base

R - length of the equivalent forces from the geometric center of the sectional area to the rotational axis

The overall output force can then be expressed as:

Foutput=l1×Ftotal_1+l2×Ftotal_2+l3×Ftotal_3lequiv(15)

Where l1,l2,l3 are moment of arm with respect to Ftotal_1,Ftotal_2,Ftotal_3. We address l1=l2=lequiv and l3=R. Equation 15 describes the relationship between pressure input P, bending angle θBending_angle and output force Foutput. Geometrically, the Foutput is proportional to the number of bellow segment N, and the thickness of bellow segment lthick. By setting Foutput as part of the cost function, geometrical optimization of the silicone rubber dimensions is realizable.

Considering the contribution of Ftotal_1 quantitatively to the total exerted force by percentage in Equation 16,

PercBellow_force_contribution=Ftotal_1Foutput×100%(16)

we found the contribution of force generated by bellow is around 35%, which means the bellows structure plays an essential role in providing force out. The larger force output refers to the large range of motion because it provides a larger power supply to compensate for the inverse force (Ftotal_3) and the resistance force from the environment.

3.2 SCASPER analytical model: the modeling of the unfolding process of the bellow structure

To characterize the quasi-static behavior of SCASPER, we first need to find the relationship between the total angle of expansion and the inflation pressure. Then we will find the total force exerted by SCASPER. All necessary diagrams for SCASPER’s modeling are outlined in Figure 9.

Figure 9
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Figure 9. Geometric diagram of SCASPER. (A) The geometric labeling of SCASPER before and after compressed. F is the force output r1 is the moment of the arm from the contact point between the airbags to the center of rotation. (B) The sectional view of one airbag before and after compression from the environment. (C) The width of each airbag from the top view. (D) The geometric labeling of the PU pipe when they are bent.

To find the relationship between the total angle of expansion of SCASPER and the pressure, we need to consider that the airbag is made out of non-extensible material and SCASPER inflates to an irregular shape. FEA simulation results were used for polynomial regression to find the angular extension as a function of pressure when there is no external loading and the airbag is not compressed as Equation 17:

ΘP=polyfitP=0.0145P2+3.0507P1.1438(17)

Θ - total extension angle of the actuator

P- inflation pressure

Referring to Figures 9A, B, when the airbag is compressed the work exerted from the environment will be converted to the change of volume of the airbag. Therefore we can characterize the volume of one airbag in Equation 18 as

ΔVP=ΔW(18)

ΔV - total volume compression on airbags

ΔW - total work exerted on the actuator from environment

Assumıng that ΔVΔΘ,

ΔVP=FΔΘR=ΔΘτ(19)

K - equivalent spring coefficient

F - force exerted to the environment

τ - torque exerted by SCASPER

ΔΘ - angular difference before and after compression

We can then set

ΔV=0L12 length 2ΔhdL(20)

Plugging in Equation 20 in Equation 19, we get the relationship between the torque and pressure applied in Equation 21:

τ=ΔVPΔΘ=12lengthLΔΘr1PΔΘ=lengthLr1P2(21)

Here we found an important conclusion that the exerted torque τ is irrelevant to ΔΘ. However, since the PU pipe would resist the extension of SCASPER when inflated, we assume the PU pipes are purely bent (Figure 9D) and apply the Euler–Bernoulli bending Equation 22 to find the internal moment of the pipe:

Mpipe =M1+M2+M3=2EIR1+EIR2+EIR3(22)

Mn - internal moment in each PU pipe

E - Young’s modulus of PU pipe

Rn - radius of the pure bending on each pipe

I - torsion moment of inertia, I=πD24D1432, D1,D2 are the internal and external diameters of pipes

Rn of each pipe can be described as:

R1=L_pipeΘ/6R2=L_pipe2Θ/6R2=L_pipe3Θ/6

or more broadly:

RN/2=L_pipeN/2Θreal /N

where N is the number of bags.

Therefore, the total torque produced by SCASPER is Mtotal =τMpipe . This Mtotal  describes the relationship between pressure input, bending angle, and torque output.

4 Experiments and results

A comprehensive set of experiments was conducted to assess the performance of LISPER and SCASPER, focusing on aspects including range of motion, force/torque versus pressure across various constrained angles, response rate, and fabrication complexity. The differences between the two actuators are detailed in Figure 4. Notably, SCASPER, owing to its inextensible layer properties, is capable of generating greater output force/torque, whereas LISPER offers reduced latency, high linearity, and relatively large output force/torque compared with previous studies. These properties play important roles in assistive motion around the shoulder and elbow.

4.1 Mechatronic system for experiments

The mechatronic system of the actuators was designed for measuring bending angles, controlling the air pressure loaded onto the actuators, and measuring the generated force. It also served to coordinate between two actuators to drive a two-degree-of-freedom human dummy arm. The system utilized a compressed pressure regulator (Hromee Compressed Filter Regulator Combo, Rohne Co. Inc.) to stabilize the inflow air compression source at 200 kPa. The inflow pipe was further connected to a proportional electronic pressure regulator (ITV2050-212BL4, SMC Corp.) to control the input pressure into the actuator. The master microcontroller implemented here was the NI myRIO-1900 development board (National Instruments Corp.), which received orientation angles at 100 Hz from the NUCLEO-F091RC development board (STMicroelectronics Corp.) via UART ports. The orientation of the actuators was measured by two JY62 IMUs (Wit-motion Inc.) located at both ends of each actuator. The IMUs provided data about the linear acceleration, angular velocity, and angular orientation (in the form of Euler angles) to the NUCLEO board (Figures 1A, B).

4.2 Pressure vs. angle and the comparison with simulation

To establish the relationship between angle and pressure, SCASPER and LISPER were mounted on an aluminum extrusion frame. Each was subjected to three inflation cycles, with pressures ranging from 10 kPa to 100 kPa for LISPER and from 10 kPa to 90 kPa for SCASPER, in increments of 10 kPa. The experimental results were then compared with FEM simulation results. As illustrated in Figure 9A, the intervention point of the experiment and simulation is slightly misaligned, which could be caused by the outward offset of the bottom plates. However, the experimental data closely match the simulation results up to 50 kPa. Beyond the intervention point of FEM, the bending angle continues to increase as the intervention surfaces slide against each other, and the discrepancy grows. The maximum bending angle of LISPER is 112.2. In Figure 4D, the discrepancy between experimental and simulated extension angles increases after the pressure reaches around 30 kPa, reaching a maximum of 43.63 at 70 kPa. The overall discrepancy for SCASPER is large, which could be attributed to the stress from the deformed air tube attached to the end of each airbag. This design deficit will be fixed in the next version of the design.

4.3 Pressure vs. force/torque relationship with different constraint angles

Force vs. pressure experiments under different bending angles were conducted for LISPER and SCASPER (Figures 4B–E), where the force was measured using a High Accuracy Digital Force Gauge (Omega Engineering Inc.). The actuators were constrained to 0°, 45°, and 60°, and each case’s measurements were conducted three times. Since LISPER’s output was modeled using force, whereas SCASPER was modeled using torque, the experiment measured the output force of LISPER and the torque of SCASPER. The corresponding moment of force was then calculated by multiplying the force with the moment arm. The force was assumed to be exerted at the tips of SCASPER. The moment of the arm was measured from the tip of either LISPER or SCASPER to their rotational axis. The inflation pressure range goes from 10 kPa to 100 kPa for SCASPER and LISPER. The maximum force and moment for SCASPER is around 5.45 Nm, and for LISPER, it is around 11.5 N.

4.4 Bandwidth analysis with sinusoidal set angle input

To find out how the rate of pressure change affects the dynamic range of motion of each unloaded pneumatic actuator, we added sinewave set pressure input to test the bandwidth of the actuators. The set angles desired are sine waves input range from 0 to 85; the analytical models map from input pressure to desired angles are generated by experimental data from Figures 4A, D by a simple polynomial fit. The specific data are provided in Table 4. For LISPER and SCASPER, the Mean Time Errors are around 0.3 s, which causes a negligible impact on patient-involved experiments. Given the elastic property of the LISPER body, the Maximum Angular Error of LISPER is much smaller than that of SCASPER. The elastic rubber pattern of SCASPER also shows its impact by decreasing the amount of Maximum Angular Error of SCASPER. One limitation we found from this experiment is that the angular errors for both actuators are generally large. This could be attributed to the limitation of the response rate of solenoid valves and the inefficient design of internal chambers. This deficiency will be solved in our further research with the help of more optimal designs for the internal chamber. One example of set angle vs. real angle for LISPER under 4-s periodic set angle input is demonstrated in the time domain in Figure 10, which shows that LISPER could follow the desired trajectory most of the time, except in the areas around the trough of the waveform. A similar situation happens to SCASPER. The severe follow-up error around low set angle input could be given to small elastic forces from the actuator bodies around the tough. SCASPER could further improve its follow-up capacity by increasing the elasticity of the strip rubber pattern.

Table 4
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Table 4. Bandwidth-related properties of LISPER and SCAPSER. Panel A Range of motion, time error, and mean error angle of LISPER. Panel B Range of motion, time error, and mean error angle of SCASPER without rubber pattern. C Range of motion, time error, and mean error angle of SCASPER with rubber pattern.

Figure 10
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Figure 10. The experiment of set angle vs real angle under 4s sine set angle input of LISPER.

4.5 Preliminary feasibility tests on dummy arm

4.5.1 Maximum bending angle test

To test the maximum bending angle driven by LISPER and SCASPER. The two actuators were positioned around the shoulder and elbow joints of a 2-DOF 3D-printed human arm to test the range of motion as shown in Figures 1C, D. To simplify the process, open-loop inflation pressures of 100 kPa and 90 kPa were set for LISPER and SCASPER, respectively. Based on the forward kinematics derived from joint angles (measured by the IMUs) to the end effect point, LISPER rotates 47.4° under 80 kPa, and SCASPER rotates 54.4° under 100 kPa. The end effect point had a maximum offset of 10.4 cm horizontally and 32.7 cm vertically.

To further verify the feasibility of the two actuators, we set two control modes commonly used in upper-limb rehabilitation training position control and gravity compensation control. The position controller drives the two actuators to push the dummy arm to desired angles whereas the active motion of participants drives the gravity compensation mode of the two actuators. The elaboration on the two controllers will be in the Supplementary Appendix.

4.6 Positional controller and gravity compensation controller

In our experiments, the elbow and shoulder joints of a 2-DOF dummy arm were controlled by sinewave inputs to achieve desired angles ranging from −10 to 30 for the elbow and 16 to 60 for the shoulder. These input range sets reflect the physically constrained range of motion of the 2-DOF arm. The shoulder was driven by SCASPER, and the elbow was driven by LISPER. As depicted in Figures 4C, F, the maximum deviation observed is approximately 8.5 at the elbow and 10.2 at the shoulder. Overall, the actual angles of both joints closely followed the set trajectories. The accompanying video demonstrates this synchronized sinewave movement. Notably, we observed relative errors around the turning points of the desired angles, likely due to the solenoid valves’ limited response capabilities when handling oscillating reference pressures.

Additionally, the gravity compensation controller was implemented based on the inverse quasi-static model and arm posture estimation. The aim was for the dummy arm to maintain three arbitrary positions, counteracting the gravitational pull. The gravity compensation test was conducted on the two joints independently and followed by a synchronized test on both joints.

5 Discussion

5.1 Comparison with previous work in mechanical design

The mechanical design for the actuators focuses on improving the range of motion, force/torque versus pressure across various constrained angles, response rate, and fabrication complexity. For context and comparison, we reference previous works in this domain Abrar et al. (2019); Irshaidat et al. (2019); Robertson et al. (2021); Zhao et al. (2015); Shiota et al. (2019); Koh et al. (2017), selecting studies that utilize similar materials (inextensible fabric or extensible silicone rubber), function as wearable robots and operate on pneumatic power. Detailed experimental outcomes are presented in Table 1. To standardize the comparison, we chose the range of motion and output force/torque at 100 kPa. The output force/torque of Robertson et al. Robertson et al. (2021) is calculated based on the linear range of motion and active linear stiffness. In Zhao et al. (2015), we chose 85 under 167 Kpa as the direct pressure vs angle curve is not provided. A reading of 4.5 N at 150 Kpa was chosen for its highly nonlinear force/torque versus pressure curve. Overall, our actuators show equivalent or better performances than the referenced works. Additionally, our devices exhibit higher linearity than those in Zhao et al. (2015). It is also noteworthy that the fabrication process, particularly the manufacturing equipment required for SCASPER, is significantly simpler compared to other fabric- or PET-based soft actuators.

In general, LISPER and SCASPER outperform all the previous works or show similar performance. We noticed the Maximum Angular Error in the response rate test across all three cases (refer to Table 1). The results demonstrate that the latency of pneumatic soft actuators, although partially mitigated by constraints on undesired extension and tunable elastic rubber patterns, still requires more advanced pneumatic systems and controller designs. With further geometric optimization, the range of motion and output force/torque can be further improved, the volumes of the actuators can be reduced, and the latency in the time domain can be attenuated.

5.2 Limitations of analytical model and controllers

The analytical model of LISPER assumes the linear property of Smooth-on Mold Max 20 which is based on the observation that the strain exerted on the silicone rubber body is less than 1. Another simplification is we assume the side walls of the bellow structure will remain flat after inflation, whereas in reality, it is partially curved.

In the analytical modeling of SCASPER, we neglect the irregular deformation of the inflated airbag and assume its cross-sectional view is triangular. The geometric parameters are set as constant and measured empirically. Apart from these, we also assume the friction between each bag is negligible. Although these assumptions can bring additional inaccuracy to the modeling, the position controller applied in this model follows up the desired trajectory accurately (Figures 4C, F), considering we included a back-loop compensation.

LISPER’s accuracy is also proven in the experimental results of the force predictions based on analytical modelings 9. (d). We noticed that in the force measurement experiment LISPER, the discrepancy between predicted force and desired force increases with pressure, which is caused by the sliding between the force gauge and LISPER.

Another assumption is the linearity between the stress and strain of the Smooth-on Mold Max 20. Although the silicone rubber is commonly a hyperelastic material, from Figure 4A. (a) it is easy to tell that the FEA simulation in free motion is a straight line, which provides support for the assumption of linear property in small-scale deformation. Another support of the linearity is from Marechal et al. (2021), where most silicone rubbers show linear stress-strain behavior within the strain range of 0–1. The team believes this assumption on linearity is not the source of modeling inaccuracy.

The gravity compensation controller, essentially an open-loop system, enables the dummy arm to maintain its position under externally applied forces, thereby validating the precision of the analytical models. This controller’s effectiveness is contingent on the accurate determination of the dummy arm’s state values. However, it’s important to note that this controller operates without back-loop error compensation, which means it does not actively correct for any deviations or errors that occur post-initial calibration. This aspect highlights a reliance on the initial accuracy of the system’s state values and may suggest a potential area for enhancement in future iterations of the controller design.

5.3 Fluctuation of preliminary test on dummy arm

The evaluation of the controller’s effectiveness was conducted using a 2-DOF (Degrees of Freedom) human dummy arm, as a substitute for human testing. This approach was chosen due to the challenges in discriminating the work contribution by humans from the actuators in a soft robot system.

A notable issue identified in the model controllers, as illustrated in Figures 4C, F and the position controller in the attached video, is the fluctuation observed around the peaks and troughs of the sine wave, particularly for the elbow joint. This phenomenon may be attributed to the limitations inherent in the solenoid valves and the quasi-static models, which overlook the effects of velocity and acceleration. When compared to the model-free PID controller, it was observed that the elbow controller (Figure 4C) exhibited increased oscillation. The shoulder PID controller demonstrated similar stability and accuracy as shown in Figure 4F, yet it also exhibited noticeable oscillation. These fluctuations could be caused by the overshot of the PID controllers rather than the design deficit of the mechanical design.

5.4 Impact of fabrication design

Our fabrication is different from many fabrications of the pouch-based structure. The fabrication design of SCASPER is largely simplified and requires only scissor cutting, 3D printed rigid frame, taping, and screwing. In contrast, many other pouch-based structures require sewing machines, heat-sealing machines, laser-cutting machines, etc. The fabrication time is largely decreased, given the concise structure design of the airbag stacks. The fabrication process of LISPER decreases the chance of air bubble trapping in complex geometric structures of the casting modes which is used to be challenging in large-size silicone rubber body fabrication. These modifications from traditional fabrication techniques guarantee the quality of soft actuators and improve the success rate of fabrication.

5.5 Future work: human-involved experiments

In the future, the two actuators will be integrated into a complete single-arm exoskeleton. Several human-involved experiments will be conducted to verify the wearability and usability of the device. The group has developed the first version of an interface to hold the actuators on the human body, as shown in Figure 11. Preliminary tests on human subjects have indicated undesired sliding between the human body and the actuators. An optimal design should be implemented to address this undesired motion. The next mechanical iteration shall focus on interface design to 1) have good alignments with human motion. 2) fit variations among different people considering their biomechanical properties.

Figure 11
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Figure 11. (A, B) shows the human subject practicing full arm extension and flexion wearing the two actuators.

Other potential research directions, following the establishment of reliable usability and wearability, include: Conducting pilot tests for rehabilitation in a clinical setting. This would involve a paradigm composed of single-joint strength training and two-joint coordination training. Developing dynamic modeling and control strategies that take into account the hysteresis of the actuators and the reduced dynamic model of the human upper limb.

6 Conclusion

In this study, we propose a new paradigm for designing bio-inspired pneumatic actuators for upper-limb rehabilitation, including the development of analytical models and fabrication processes. Furthermore, we conducted experiments to verify the dynamic properties of the two actuators and their coordinated performance on a mannequin arm. Specifically, we proposed the LISPER and SCASPER actuators for the elbow and shoulder, respectively. The LISPER actuator features detailed bellow-shaped folds, meshes, and braces, offering excellent performance in terms of rango of motion, output force/torque, and linearity. In contrast, the SCASPER actuator is designed for time-efficient fabrication, with adjustable linear output force/torque achieved by modifying the silicone rubber strip pattern. It provides sufficient output force/torque to enable a wide range of motion and effectively support shoulder flexion.

The actuators were combined as a mechatronic system and deployed with position control and gravity compensation control mode to evaluate their practical performance. Although the system exhibited slight fluctuations at certain points of the working range, the two-degree-of-freedom system tracked the desired trajectories stably under position control and maintained the desired position under gravity compensation mode.

However, both soft actuators showed relatively large peak error values during high-speed repetitions, which can be attributed to limitations in pneumatic drivers, control strategies, and the geometric design parameters of the chambers. These limitations, along with other potential improvements discussed in the manuscript, will be addressed in our future research.

Our results indicate that this actuator design paradigm has significant potential for further development in future work. By refining and optimizing the design principles outlined in this study, researchers could enhance the functionality and versatility of pneumatic actuators for various applications, particularly in rehabilitation and assistive technologies. Future research could explore adapting these actuators for different joints or movements, integrating more advanced control strategies, and improving material properties to enhance durability and performance in real-world settings.

Data availability statement

The original contributions presented in the study are included in the article/Supplementary Material, further inquiries can be directed to the corresponding author.

Author contributions

HZ: Conceptualization, Data curation, Formal Analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing–original draft, Writing–review and editing. GN: Conceptualization, Data curation, Formal Analysis, Investigation, Methodology, Visualization, Writing–review and editing. JB: Visualization, Writing–review and editing. ZW: Investigation, Methodology, Writing–review and editing. AH: Investigation, Methodology, Writing–review and editing. AD: Conceptualization, Supervision, Validation, Writing–review and editing, Funding acquisition, Resources.

Funding

The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. The funding is from ReNeu Lab's general deposite.

Acknowledgments

The team would like to thank Zonghuan Wu for providing technical support on sensors and embedded systems, and Ashwin Hingwe designed wearable mechanical settings to mount the actuators on experimental platforms and human subjects.

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Supplementary material

The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/frobt.2024.1451231/full#supplementary-material

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Keywords: index terms-pneumatic soft actuators, bio-inspired design, analytical modeling, wearable devices, exoskeleton

Citation: Zhang H, Naquila G, Bae J, Wu Z, Hingwe A and Deshpande A (2024) Novel bio-inspired soft actuators for upper-limb exoskeletons: design, fabrication and feasibility study . Front. Robot. AI 11:1451231. doi: 10.3389/frobt.2024.1451231

Received: 18 June 2024; Accepted: 10 September 2024;
Published: 16 October 2024.

Edited by:

Yilun Sun, Technical University of Munich, Germany

Reviewed by:

Mahdi Haghshenas-Jaryani, New Mexico State University, United States
Zengwei Wang, Technical University of Munich, Germany

Copyright © 2024 Zhang, Naquila, Bae, Wu, Hingwe and Deshpande. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Haiyun Zhang, aGFpeXVuemhhbmdAdXRleGFzLmVkdQ==; Ashish Deshpande, YXNoaXNoQGF1c3Rpbi51dGV4YXMuZWR1

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.