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REVIEW article

Front. Public Health
Sec. Infectious Diseases: Epidemiology and Prevention
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1498445

COVID-19 Clinical Presentation, Management, and Epidemiology: A Concise Compendium

Provisionally accepted
David P Maison David P Maison 1,2*Hawi Tasissa Hawi Tasissa 3Amelia Deitchman Amelia Deitchman 3Michael J Peluso Michael J Peluso 4Youping Deng Youping Deng 5F DeWolfe Miller F DeWolfe Miller 6Timothy J Henrich Timothy J Henrich 2Mariana Gerschenson Mariana Gerschenson 1*
  • 1 Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Mānoa, Honolulu, Hawaii, United States
  • 2 Division of Experimental Medicine, Department of Medicine, School of Medicine, University of California San Francisco, San Francisco, United States
  • 3 Department of Clinical Pharmacy, University of California San Francisco, San Francisco, United States
  • 4 Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, School of Medicine, University of California San Francisco, San Francisco, United States
  • 5 Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii at Mānoa, Honolulu, Hawaii, United States
  • 6 Department of Tropical Medicine, Medical Microbiology & Pharmacology, John A. Burns School of Medicine, University of Hawaii at Mānoa, Honolulu, Hawaii, United States

The final, formatted version of the article will be published soon.

    Coronavirus Disease 2019, caused by severe acute respiratory coronavirus 2, has been an everevolving disease and pandemic, profoundly impacting clinical care, drug treatments, and understanding. In response to this global health crisis, there has been an unprecedented increase in research exploring new and repurposed drugs and advancing available clinical interventions and treatments. Given the widespread interest in this topic, this review aims to provide a current summary -for interested professionals not specializing in COVID-19 -of the clinical characteristics, recommended treatments, vaccines, prevention strategies, and epidemiology of COVID-19. The review also offers a historical perspective on the pandemic to enhance understanding.

    Keywords: COVID-19, SARS-CoV-2, Clinical presentation, Epidemiology, Risk factors, Vaccines, treatments, Public Health

    Received: 27 Sep 2024; Accepted: 21 Jan 2025.

    Copyright: © 2025 Maison, Tasissa, Deitchman, Peluso, Deng, Miller, Henrich and Gerschenson. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    David P Maison, Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Mānoa, Honolulu, 96813-5534, Hawaii, United States
    Mariana Gerschenson, Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Mānoa, Honolulu, 96813-5534, Hawaii, United States

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.