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ORIGINAL RESEARCH article

Front. Psychol.
Sec. Health Psychology
Volume 16 - 2025 | doi: 10.3389/fpsyg.2025.1522536

Sleep as a Mediator Between Chronic Diseases and Depression: A NHANES Study (2005-2018)

Provisionally accepted
Cuixiao Wang Cuixiao Wang *Ming Tan Ming Tan Haihong Zhao Haihong Zhao Yaru nie Yaru nie pingping deng pingping deng
  • Department of Anatomy, Basic Medical College, Guangxi Medical University, Nanning, China

The final, formatted version of the article will be published soon.

    Objective: This article investigates the relationship between common chronic diseases and depression among US adults and examines the mediating role of sleep in this relationship, using a cross-sectional study to offer recommendations for depression prevention. Methods: This study analyzed data from 10,710 participants collected from the National Health and Nutrition Examination Survey (NHANES) between 2005 and 2018. Logistic regression, subgroup analysis, restricted cubic spline (RCS) analysis, and mediation analysis were employed to explore the relationship between common chronic diseases and depression, and the mediating role of sleep.

    Keywords: Chronic Disease, Trouble sleeping, Sleep hours, Depression, Mediation

    Received: 14 Nov 2024; Accepted: 02 Jan 2025.

    Copyright: © 2025 Wang, Tan, Zhao, nie and deng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Cuixiao Wang, Department of Anatomy, Basic Medical College, Guangxi Medical University, Nanning, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.