Skip to main content

ORIGINAL RESEARCH article

Front. Psychol.

Sec. Psycho-Oncology

Volume 16 - 2025 | doi: 10.3389/fpsyg.2025.1491734

Reduction of death anxiety in patients with advanced cancer in shortterm psychotherapy

Provisionally accepted
  • Department of Medical Psychology and Medical Sociology, University Hospital Leipzig, Leipzig, Germany

The final, formatted version of the article will be published soon.

    Death anxiety has increasingly become the focus of research in recent years. So far, we know little about the reduction of death anxiety through psychotherapeutic interventions in patients with advanced cancer and possible predictors of this reduction. The aim of this study is to investigate the extent to which death anxiety is reduced during the course of psychotherapeutic interventions and whether specific socio-demographic, psychological or medical variables can predict such reduction over time.This study is a secondary data analysis of the randomized controlled trial of Managing Cancer and Living Meaningfully (CALM) Therapy, a short-term psychotherapy used to reduce depression and psychological distress in patients with advanced cancer. The active control group, a non-specific psychotherapeutic counselling intervention (SPI), showed equal effects on depression and distress and consequently both groups are investigated together in this study. Within the present study, we analyze the reduction of death anxiety from baseline to 3and 6-months follow-up. Data were collected using validated questionnaires; death anxiety was assessed using an adapted version of the Death and Dying Distress Scale (DADDS). Predictors of the reduction of death anxiety were investigated using multiple linear regression models. Results: The sample comprised 194 patients (average age 58 years, 62% female, all with a UICC stage of III or IV). There was a significant reduction of death anxiety over time, in particular between the baseline and 3 months follow-up (t (148) = 5.26, p < .001, d = 0.43) and the baseline and 6 months follow-up (t (120) = 5.48, p < .001, d = 0.50). The UICC disease stage III (p = 0.05) and an elevated death anxiety score/level at baseline (p = 0.01) were found to be predictors for the reduction of death anxiety. No further predictors were found within the study.The results suggest that psychotherapeutic interventions could reduce death anxiety in patients with advanced cancer. A time effect cannot be excluded and further studies using a care-as-usual control group are necessary. Nevertheless, this study sheds light on the role that psychotherapeutic interventions play in reducing death anxiety and complements the use of palliative medical treatments to alleviate patients' discomfort.

    Keywords: Psychooncology, psychooncological intervention, palliative psychologists, palliative psychological support, calm

    Received: 05 Sep 2024; Accepted: 19 Mar 2025.

    Copyright: © 2025 Oberth, Springer, Lehmann-Laue and Mehnert-Theuerkauf. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Paula Oberth, Department of Medical Psychology and Medical Sociology, University Hospital Leipzig, Leipzig, Germany

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

    Research integrity at Frontiers

    Man ultramarathon runner in the mountains he trains at sunset

    94% of researchers rate our articles as excellent or good

    Learn more about the work of our research integrity team to safeguard the quality of each article we publish.


    Find out more