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ORIGINAL RESEARCH article

Front. Psychol.
Sec. Health Psychology
Volume 16 - 2025 | doi: 10.3389/fpsyg.2025.1478765

Relationship between accelerometer-measured physical activity and depressive symptoms in hemodialysis patients with comorbid diabetes mellitus: a multicenter cross-sectional study

Provisionally accepted
Ruiting Liang Ruiting Liang 1,2Xiaoyu Chen Xiaoyu Chen 2Gaowa Siqin Gaowa Siqin 3Zhixin Zhang Zhixin Zhang 1,2Shumei Zhang Shumei Zhang 3Lihua Li Lihua Li 3Sarna Talin Sarna Talin 3Qi Guo Qi Guo 2*
  • 1 Tianjin Key Laboratory of Exercise Physiology and Sports Medicine, School of Social Sports and Health Sciences, Tianjin University of Sport, Tianjin, China
  • 2 Department of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China
  • 3 Department of Cardiovascular, Inner Mongolia People's Hospital, Hohhot, Inner Mongolia Autonomous Region, China

The final, formatted version of the article will be published soon.

    The objective of this study was to examine the association between accelerometerderived moderate-to-vigorous physical activity (MVPA) and depressive symptoms in hemodialysis patients with and without type 2 diabetes mellitus (T2DM).This cross-sectional study finally included 450 maintenance hemodialysis patients (male 281, average age 62 years) from seven dialysis centers in Shanghai, China.Physical activity(PA) was measured using the triaxial accelerometer (ActiGraph GT3X+, Pensacola, FL, USA). We measured depressive symptoms using the 9-item Patient Health Questionnaire (PHQ-9) (PHQ-9⩾10). We categorized physical activity into quartile groups (Q1 through Q4), with the first quartile defined as low engagement and the remaining quartiles defined as moderate to high engagement. We used logistic regression and trend test to analyze the relationship between quartile groups and depressive symptoms. The analyses in this study adjusted for a range of confounders.Results: The prevalence of depression was higher in patients with hemodialysis combined with T2DM (17.2%). In diabetic patients, MVPAQ4 was negatively associated with depression after adjusting for covariates [OR=0.076; 95% confidence interval (CI)=0.006-0.955, p=0.046]. However, in non-diabetic hemodialysis patients, no significant association was found between MVPAQ1-Q4 and depression after adjusting for covariates (p > 0.05).Moderate-to-vigorous physical activity was associated with depression in the diabetic hemodialysis group, but not in the non-diabetic group. Further studies are needed to investigate more causal relationships between MVPA and depressive symptoms in patients with T2DM.

    Keywords: accelerometer, depressive symptoms, hemodialysis, Moderate-to-vigorous physical activity, type 2 diabetes mellitus

    Received: 14 Oct 2024; Accepted: 14 Jan 2025.

    Copyright: © 2025 Liang, Chen, Siqin, Zhang, Zhang, Li, Talin and Guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Qi Guo, Department of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China

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