Arthur Trognon ^1,2,3* Natacha Stortini ^1,2 Coralie Duman ^1,2 Nami Koïdé ¹ Ewa Skupinska ^1,4 Hamza Altakroury ¹ Alizée Poli ^1,5 Loann Mahdar-Recorbet ^1,6 Blandine Beaupain ^7,8,9 Jean Donadieu ^7,8,9 Michel Musiol ^10,2,3

• ¹ CLINICOG, Nancy, France
• ² Université de Lorraine, Nancy, Lorraine, France
• ³ UMR7118 Analyse et Traitement Informatique de la Langue Française (ATILF), Nancy, Lorraine, France
• ⁴ Université de Strasbourg, Strasbourg, Alsace, France
• ⁵ Université Paris-Saclay, Saint Aubin, France
• ⁶ Independent researcher, Lyon, France
• ⁷ Assistance Publique Hopitaux De Paris, Paris, Île-de-France, France
• ⁸ Hôpital Armand Trousseau, Paris, France
• ⁹ Other, Paris, France
• ¹⁰ Inria Nancy - Grand-Est research centre, Villers-lès-Nancy, France

Background: Shwachman-Diamond Syndrome (SDS) is a rare genetic disorder with documented cognitive and behavioral challenges. However, its socio-pragmatic dynamics remain underexplored, particularly in cooperative interactions where social norms and economic considerations intersect.Objective: This study investigates the socio-behavioral dynamics of SDS, focusing on how children with the condition navigate cooperative interactions. Using computational pragmatics, we aimed to identify the underlying principles guiding their social behavior. Methods: A cohort of 10 children (5 SDS, 5 matched controls) participated in ecological and cognitive tasks, including the WISC-V "Comprehension" subtest, NEPSY-II social perception tasks, and the Trognon Ecological Side Task for the Assessment of Speech-Act Processing (TEST-ASAP). Dialogues were analyzed using the Topological and Kinetic (2TK) model and a Recurrent Neural Network (RNN), enabling fine-grained computational insights into their interaction patterns.Results: Children with SDS exhibited cooperative behaviors shaped by perceived economic benefits, often at the expense of established social norms. Unlike behaviors classically observed in other pathologies such as autism spectrum disorders, where responses are influenced by the directness of communication, SDS behaviors were driven by personal gain, regardless of the indirectness of requests. Computational analyses revealed strong divergences in dialogical alignment when tasks lacked direct benefits, even with corrective prompts.Insights from Computational Pragmatics 2 Conclusions: SDS children demonstrate a transactional approach to social interactions, prioritizing personal benefits over cooperative norms. Neuroimaging interpretation from previous studies suggest these behaviors may stem from atypical processing in the anterior cingulate and orbitofrontal cortex, regions critical for valuing social rewards. These findings highlight the need for targeted interventions to improve pragmatic skills and adaptive functioning in SDS, considering their unique behavioral profiles.