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ORIGINAL RESEARCH article
Front. Psychol.
Sec. Psycho-Oncology
Volume 15 - 2024 |
doi: 10.3389/fpsyg.2024.1444522
Psychiatric disorders in patients with benign and malignant sinonasal tumors: a prospective cross-sectional study
Provisionally accepted
Guang-Ye Zhan
1*
Hui-Fang Wang
2*
Dong-Fang Wang
2*
Yihui Wen
2
Hua Zhong
2
Weiping Wen
2
Jian Li
2*
Liang Peng
2*- 1 Sanming First Hospital, Fujian Medical University, Sanming, China
- 2 The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Objective: To assess the prevalence of depression, anxiety, insomnia, and somatic symptom disorder (SSD) in patients with benign and malignant sinonasal tumors.: Pretreatment patients with sinonasal tumors were prospectively recruited on the rhinology ward of a tertiary hospital from July 2021 to March 2022. The electronic questionnaire which contains the rhinological symptom scale, 22-item Sinonasal Outcome Test (SNOT-22) scale, Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), Insomnia Severity Index (ISI), and Patient Health Questionnaire-15 (PHQ-15) was filled out by patients at admission. The associations between symptom /SNOT-22 scores and scores of psychometric tests were assessed by the Pearson correlation coefficient (r) and simple linear regression. Receiver operating characteristic (ROC) analysis was used to evaluate the performance of the SNOT-22 score in predicting psychiatric disorders.Results: Thirteen patients with benign sinonasal tumors and fifteen patients with malignant sinonasal tumors were recruited. The benign and malignant groups did not differ significantly regarding symptomatology and mental well-being. Of the total patients, 9 were at risk of depression (PHQ-9 > 4), 10 were at risk of anxiety (GAD-7 > 4), 11 were at risk of insomnia (ISI > 7), and 11 were at risk of SSD (PHQ-15 > 4). The overall symptom, facial pain/pressure, postnasal drip, and SNOT-22 scores were positively associated with scores of psychometric tests. Patients with a high SNOT-22 score (> 18) are likely to be affected by comorbid psychiatric disorders.When interpreting the results of this study, it should be noted that screening tools, not diagnostic tools, were used to identify psychiatric risk.Depression, anxiety, insomnia, and SSD are prevalent in patients with sinonasal tumors. Otolaryngologists should have a low threshold to ask the patient about psychiatric symptoms, especially for patients with a SNOT-22 score > 18.
Keywords: Depression, Anxiety, insomnia, Somatic symptom disorder, sinonasal tumor
Received: 11 Jun 2024; Accepted: 26 Nov 2024.
Copyright: © 2024 Zhan, Wang, Wang, Wen, Zhong, Wen, Li and Peng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Guang-Ye Zhan, Sanming First Hospital, Fujian Medical University, Sanming, 365000, China
Hui-Fang Wang, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Dong-Fang Wang, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Jian Li, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Liang Peng, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
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