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SYSTEMATIC REVIEW article

Front. Psychol.
Sec. Psycho-Oncology
Volume 15 - 2024 | doi: 10.3389/fpsyg.2024.1435110

Effect of Cognitive-Behavioral Therapy on Fatigue in Cancer Patients: A Systematic Review and Meta-Analysis

Provisionally accepted
Parisa Hosseini Koukamari Parisa Hosseini Koukamari 1Mahmood Karimy Mahmood Karimy 1*Mohtasham Ghaffari Mohtasham Ghaffari 2*Alireza Milajerdi Alireza Milajerdi 3*
  • 1 Social Determinants of Health Research Center, Saveh University of Medical Sciences, Saveh, Markazi, Iran
  • 2 Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Alborz, Iran
  • 3 Research Center for Biochemistry and Nutrition in MetabolicDiseases, Kashan University of Medical Sciences, Kashan, Isfahan, Iran

The final, formatted version of the article will be published soon.

    Background: Fatigue is a prevalent issue among cancer patients. Cognitive Behavioral Therapy (CBT) is an individualized intervention that empowers patients and caregivers to actively participate in the treatment process. A recent systematic review and meta-analysis have examined the impact of CBT on fatigue in cancer patients. Methods: Articles published up to April 2023 were systematically searched in Scopus, PubMed, and Web of Science using relevant keywords. All randomized clinical trials (RCTs) investigating the effects of CBT on fatigue in cancer patients were included. Statistical analyses were conducted using Stata version 14, with a significance level set at p< 0.05. Results: The current systematic review and meta-analysis encompassed 10 RCTs. CBT demonstrated a significant reduction in fatigue scores among cancer patients [Standardized Mean Difference (WMD): -2.50; 95%CI: -3.43, -1.56; I2= 95.8%, p<0.001]. This effect was consistent across all subgroup analyses.This study underscores the significant impact of CBT on fatigue in cancer patients.Further randomized clinical trials focusing on various cancer types are warranted to validate and build upon these findings.

    Keywords: Cancer, cbt, CRF, Fatigue, Cancer-related fatigue, cognitive behavioral therapy

    Received: 26 May 2024; Accepted: 13 Dec 2024.

    Copyright: © 2024 Hosseini Koukamari, Karimy, Ghaffari and Milajerdi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Mahmood Karimy, Social Determinants of Health Research Center, Saveh University of Medical Sciences, Saveh, Markazi, Iran
    Mohtasham Ghaffari, Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Alborz, Iran
    Alireza Milajerdi, Research Center for Biochemistry and Nutrition in MetabolicDiseases, Kashan University of Medical Sciences, Kashan, 87137.81147, Isfahan, Iran

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.