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ORIGINAL RESEARCH article

Front. Psychol.
Sec. Psychology for Clinical Settings
Volume 15 - 2024 | doi: 10.3389/fpsyg.2024.1376257

Cross-sectional survey to determine fatigue in patients with systemic lupus erythematosus

Provisionally accepted
Jingya Lu Jingya Lu Minmin Yu Minmin Yu Rong Xu Rong Xu *
  • The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China

The final, formatted version of the article will be published soon.

    Background: Fatigue is a prevalent symptom among individuals with active systemic lupus erythematosus (SLE). We aimed to investigate the status quo and influencing factors of fatigue in patients with SLE, to provide insights to the clinical SLE treatment and care.Methods: We conducted a longitudinal survey on the fatigue of active SLE patients from June 2022 to November 2023 in our hospital. Fatigue severity scale (FSS), Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) were used for data collection. Pearson correlation and multiple stepwise regression analysis were conducted to analyze the relevant factors affecting the fatigue level of patients with SLE.Results: A total of 212 active SLE patients were included, the incidence of fatigue in active SLE patients was 55.66%. There were statistical differences in the fatigue score between SLE patients with different age and course of SLE (all P<0.05). Fatigue was positively correlated with anxiety (r = 0.559) and depression (r = 0.591) in patients with SLE (all P<0.05). Multiple stepwise regression analysis indicated that age, course of SLE, anxiety and depression were the influencing factors of fatigue in SLE patients (all P<0.05).Conclusions: Patients with SLE exhibit a significant degree of fatigue, which varies with respect to age, disease duration, and the presence of comorbid anxiety and depression. It is imperative that healthcare providers closely monitor the fatigue levels in this patient population and implement targeted interventions to mitigate the impact of fatigue on the quality of life and overall well-being of individuals with SLE.

    Keywords: Fatigue, systemic lupus erythematosus, Treatment, care, clinical

    Received: 25 Jan 2024; Accepted: 09 Jul 2024.

    Copyright: © 2024 Lu, Yu and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Rong Xu, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu Province, China

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