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ORIGINAL RESEARCH article
Front. Physiol.
Sec. Medical Physics and Imaging
Volume 16 - 2025 | doi: 10.3389/fphys.2025.1457197
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Objective: This This study aims to enhance the efficiency and accuracy of thyroid nodule segmentation in ultrasound images, ultimately improving nodule detection and diagnosis. For clinical deployment on mobile and embedded devices, DeepLabV3+ strives to achieve a balance between a lightweight architecture and high segmentation accuracy. Methodology: A comprehensive dataset of ultrasound images was meticulously curated using a high-resolution ultrasound imaging device. Data acquisition adhered to standardized protocols to ensure high-quality imaging. Preprocessing steps, including noise reduction and contrast optimization, were applied to enhance image clarity. Expert radiologists provided ground truth labels through meticulous annotation. To improve segmentation performance, we integrated MobileNetV2 and Depthwise Separable Dilated Convolution into the Atrous Spatial Pyramid Pooling (ASPP) module, incorporating the Pyramid Pooling Module (PPM) and attention mechanisms. To mitigate classification imbalances, we employed Tversky loss functions in the ultrasound image classification process. Results: In semantic image segmentation, DeepLabV3+ achieved an impressive Intersection over Union (IoU) of 94.37%, while utilizing only 12.4MB of parameters, including weights and biases. This remarkable accuracy demonstrates the effectiveness of our approach. A high IoU value in medical imaging analysis reflects the model's ability to accurately delineate object boundaries. Conclusion: DeepLabV3+ represents a significant advancement in thyroid nodule segmentation, particularly for thyroid cancer screening and diagnosis. The obtained segmentation results suggest promising directions for future research, especially in the early detection of thyroid nodules. Deploying this algorithm on mobile devices offers a practical solution for early diagnosis and is likely to improve patient outcomes.
Keywords: DeepLabV3+, Thyroid nodule segmentation, ultrasound imaging, MobileNetV2, Attention mechanisms, Tversky Loss Function, medical imaging
Received: 30 Jun 2024; Accepted: 26 Feb 2025.
Copyright: © 2025 Yanga, Ashraf, Riaz, Huang and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Changan Yanga, a Department of Thyroid and Breast Surgery, Jinjiang Municipal Hospital, Quanzhou, Fujian Province, 362200, China., Quanzhou, Fujian Province, China
Mudassar Riaz, School of Information Engineering, Chang’an University, Xi’an, Shaanxi Province,710000, PR China, Xian, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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