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REVIEW article

Front. Physiol.
Sec. Vascular Physiology
Volume 15 - 2024 | doi: 10.3389/fphys.2024.1461519

The Causes of Pulmonary Hypertension and the Benefits of Aerobic Exercise for Pulmonary Hypertension from an Integrated Perspective

Provisionally accepted
Yinping Song Yinping Song 1*Yingping Song Yingping Song 1*Hao Jia Hao Jia 2Qing Ma Qing Ma 1*Lulu Zhang Lulu Zhang 1Xiangyi Lai Xiangyi Lai 1*Youhua Wang Youhua Wang 2
  • 1 School of Physical Education, Xi'an Fanyi University, Xi'an, Shanxi, China
  • 2 School of Physical Education, Shaanxi Normal University, Xi'an, China

The final, formatted version of the article will be published soon.

    Pulmonary hypertension is a progressive disease of the pulmonary arteries that begins with increased pulmonary artery pressure, driven by progressive remodeling of the small pulmonary arteries, and ultimately leads to right heart failure and death.Vascular remodeling is the main pathological feature of pulmonary hypertension, but treatments for needle pulmonary hypertension are lacking. Determining the process of vascular proliferation and dysfunction may be a way to decipher the pathogenesis of pulmonary hypertension. In this review, we summarize the important pathways of pulmonary hypertension pathogenesis. We show how these processes are integrated and emphasize the benign role of aerobic exercise, which, as an adjunctive therapy, may be able to modify vascular remodeling in pulmonary hypertension.

    Keywords: pulmonary hypertension, aerobic exercise, er stress, ROS, Thrombosis, 6-minute walk distance

    Received: 08 Jul 2024; Accepted: 26 Sep 2024.

    Copyright: © 2024 Song, Song, Jia, Ma, Zhang, Lai and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yinping Song, School of Physical Education, Xi'an Fanyi University, Xi'an, 71010, Shanxi, China
    Yingping Song, School of Physical Education, Xi'an Fanyi University, Xi'an, 71010, Shanxi, China
    Qing Ma, School of Physical Education, Xi'an Fanyi University, Xi'an, 71010, Shanxi, China
    Xiangyi Lai, School of Physical Education, Xi'an Fanyi University, Xi'an, 71010, Shanxi, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.