Frontiers in Pharmacology | Translational Pharmacology

Clinical Trial

Published on 19 Mar 2025

The adjunctive role of metformin in patients with mild to moderate ulcerative colitis: a randomized controlled study

in Translational Pharmacology

Ammena Y. Binsaleh
Sahar M. El-Haggar
Sahar K. Hegazy
Maha M. Maher
Monir M. Bahgat
Thanaa A. Elmasry
Sarah Alrubia
Amsha S. Alsegiani
Mamdouh Eldesoqui
Mostafa M. Bahaa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1507009

488 views

Original Research

Published on 19 Mar 2025

Metformin as a disease-modifying therapy in osteoarthritis: bridging metabolism and joint health

in Translational Pharmacology

Iryna Halabitska
Pavlo Petakh
Oleksandr Kamyshnyi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1567544

307 views

Original Research

Published on 19 Mar 2025

Sex differences in metabolic regulation by Gi/o-coupled receptor modulation of exocytosis

in Translational Pharmacology

Montana Young
Ryan P. Ceddia
Analisa Thompson-Gray
David Reyes
Jackson B. Cassada
Julio E. Ayala
Owen P. McGuinness
Sheila Collins
Heidi E. Hamm

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544456

507 views

Review

Published on 19 Mar 2025

Functional tumor-derived exosomes in NSCLC progression and clinical implications

in Translational Pharmacology

Yuxin Gao
Jun Xie
Zhenya Yang
Mengxi Li
Hongfan Yuan
Rui Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1485661

270 views

Original Research

Accepted on 17 Mar 2025

Development of an adipocyte differentiation protocol using 3T3-L1 cells for the investigation of the browning process: identification of the PPARγ agonist rosiglitazone as a browning reference drug

in Translational Pharmacology

Lorenzo Flori
Giulia Galgani
Giorgia Bray
Chiara Ippolito
Cristina Segnani
Carolina Pellegrini
Valentina Citi
NUNZIA BERNARDINI
Alma Martelli
Vincenzo Calderone

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546456

110 views

Editorial

Published on 14 Mar 2025

Editorial: The potential of transferrin as a drug target and drug delivery system

in Translational Pharmacology

Patricia Carrilho
Sidharth Chopra
Mallikarjuna Rao Pichika
Robert E. Fleming
Nermi L. Parrow

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584190

358 views

Original Research

Accepted on 13 Mar 2025

HPLC-UV method development and validation for anticancer drug sorafenib and the co-prescribed drug dexamethasone: Application to pharmacokinetic evaluation of sorafenib nanoformulations HPLC-UV method development and validation for anticancer drug sorafenib and co-prescribed drugs: Application to pharmacokinetic evaluation of sorafenib nanoformulations

in Translational Pharmacology

Abdul Mateen
Abad Khan
Ismail Khan
Saifullah Khan Khalil
Lateef Ahmad
Muhammad Junaid
Saqib Jehan
Muhammad Sohail Anwar
Muhammad Faheem
Abdul Salam

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1442762

Original Research

Published on 05 Mar 2025

Sodium nitrate regulates senescence accompanied by aortic atherosclerosis in ApoE−/− mice through the miR-34a/FGF-21 axis

in Translational Pharmacology

Ning Tao
Zhichao He
Han Duan
Liang Wang
Jing Yi
Jingyuan Shao
Lin Lv
Junzhao Duan
Hu Cao
Xiwen Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562321

543 views

Brief Research Report

Published on 03 Mar 2025

SysNatMed: rational natural medicine discovery by systems genetics

in Translational Pharmacology

Chang-Qing Ye
Jie Leng
Meng-Yuan Jin
Yuan-Dong Meng
Zi-Yi Zhao
Fan-Xing Meng
Xuan Xu
Sha-Sha Fan
Hong-Bin Luo
Xiang-Yu Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1496061

732 views

Original Research

Published on 26 Feb 2025

Knowledge structure and dynamic evolution of nanomedicine in liver cancer research: a scientometric analysis and visualization

in Translational Pharmacology

Shaodong Li
Dapeng Cui
Bo Shao
Zhenhua Kang
Guoqiang Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1509259

715 views

Review

Published on 26 Feb 2025

Muscle loss in cancer cachexia: what is the basis for nutritional support?

in Translational Pharmacology

Jaline Faiad
Márcia Fábia Andrade
Gabriela de Castro
Joyce de Resende
Marina Coêlho
Giovana Aquino
Marilia Seelaender

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519278

793 views

Original Research

Published on 17 Feb 2025

A double-layer PLGA/CoI-MeHA tissue engineering scaffold for urethral reconstruction

in Translational Pharmacology

Mingyang Chang
Qinyuan Tan
Ge Bian
Ming Zhang
Jianing Lv
Junjie Su
Xiaoqing Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555183

543 views

Review

Published on 13 Feb 2025

Exploring the application of metal-based photothermal agents in photothermal therapy combined with immune checkpoint therapy

in Translational Pharmacology

Bin Xie
ZhiRong Xiao
JiaBao Ling
Yichao Peng
Tianfeng Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553158

587 views

Original Research

Published on 12 Feb 2025

Digital twin-enhanced three-organ microphysiological system for studying drug pharmacokinetics in pregnant women

in Translational Pharmacology

Katja Graf
José Martin Murrieta-Coxca
Tobias Vogt
Sophie Besser
Daria Geilen
Tim Kaden
Anne-Katrin Bothe
Diana Maria Morales-Prieto
Behnam Amiri
Stephan Schaller

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528748

2,406 views

Review

Published on 12 Feb 2025

Advances in hydrogel for diagnosis and treatment for Parkinson’s disease

in Translational Pharmacology

Peining Zhu
Zenghui Zhao
Yufei Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552586

928 views

Brief Research Report

Published on 31 Jan 2025

Metformin dosage and galectin-3 levels: insights from PCOS patients preparing for IVF

in Translational Pharmacology

Valentina N. Nikolić
Milan Stefanović
Dejan Mitić
Slavica Sunarić
Vladana Stojiljkovic
Hristina Trajković
Aleksandra Ignjatović
Dragana Stokanović

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505022

860 views