Frontiers in Pharmacology | Translational Pharmacology

Original Research

Accepted on 17 Feb 2025

Sodium nitrate regulates senescence accompanied by aortic atherosclerosis in ApoE -/-mice through the miR-34a/FGF-21 axis

in Translational Pharmacology

Ning Tao
Zhichao He
Han Duan
Liang Wang
Jing Yi
Jingyuan Shao
Lin Lv
Junzhao Duan
Hu Cao
Xiwen Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562321

Original Research

Accepted on 17 Feb 2025

Male Mice Treated with Combined Anti-Fibrotic Therapeutics, IPW5371 and Tadalafil, are Predisposed to Adverse Cardiovascular Events

in Translational Pharmacology

Jazz Stephens
Uriel Blas-Machado
Chrissy Sherrill
David Caudell
Nancy Kock
Ashley Davis
Jordyn Whitfield
Barry Hart
Kylie Kavanagh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537494

Original Research

Published on 17 Feb 2025

A double-layer PLGA/CoI-MeHA tissue engineering scaffold for urethral reconstruction

in Translational Pharmacology

Mingyang Chang
Qinyuan Tan
Ge Bian
Ming Zhang
Jianing Lv
Junjie Su
Xiaoqing Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555183

140 views

Clinical Trial

Accepted on 14 Feb 2025

The Adjunctive Role of Metformin in Patients with Mild to Moderate Ulcerative Colitis: A Randomized Controlled Study

in Translational Pharmacology

Mostafa Bahaa
Ammena Y Binsaleh
Sahar M El-Haggar
Sahar K Hegazy
Maha M Maher
Monir M Bahgat
Thanaa A Elmasry
Sarah Alrubia
Amsha S Alsegiani
Mamdouh Eldesouqui

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1507009

Review

Published on 13 Feb 2025

Exploring the application of metal-based photothermal agents in photothermal therapy combined with immune checkpoint therapy

in Translational Pharmacology

Bin Xie
ZhiRong Xiao
JiaBao Ling
Yichao Peng
Tianfeng Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553158

152 views

Original Research

Accepted on 12 Feb 2025

Potential effects of lipid lowering and antioxidant activity of exosomes from Phascolosoma esculenta: In vivo and in vitro Studies

in Translational Pharmacology

Lin Yang
Xue Yi
Duan Meitao
Ahmed Mahal
Binbin Chen
Zhiqiang Zhang
Jungang Ren
Ming Chen
Chen Meng
Moxun Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1560462

Original Research

Published on 12 Feb 2025

Digital twin-enhanced three-organ microphysiological system for studying drug pharmacokinetics in pregnant women

in Translational Pharmacology

Katja Graf
José Martin Murrieta-Coxca
Tobias Vogt
Sophie Besser
Daria Geilen
Tim Kaden
Anne-Katrin Bothe
Diana Maria Morales-Prieto
Behnam Amiri
Stephan Schaller

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528748

838 views

Review

Published on 12 Feb 2025

Advances in hydrogel for diagnosis and treatment for Parkinson’s disease

in Translational Pharmacology

Peining Zhu
Zenghui Zhao
Yufei Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552586

225 views

Brief Research Report

Accepted on 11 Feb 2025

SysNatMed: rational natural medicine discovery by systems genetics

in Translational Pharmacology

Chang-Qing Ye
Jie Leng
Meng-Yuan Jin
Yuan-Dong Meng
Zi-Yi Zhao
Fan-Xing Meng
Xuan Xu
Sha-Sha Fan
Hong-Bin Luo
Xiang-Yu Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1496061

Original Research

Accepted on 07 Feb 2025

Sex Differences in Metabolic Regulation by Gi/o-coupled Receptor Modulation of Exocytosis

in Translational Pharmacology

Montana Young
Ryan P Ceddia
Analisa Thompson-Gray
David Reyes
Jackson B Cassada
Julio E Ayala
Owen P Mcguinness
Sheila Collins
Heidi Hamm

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544456

Original Research

Accepted on 07 Feb 2025

Knowledge Structure and Dynamic Evolution of Nanomedicine in Liver Cancer Research: A Scientometric Analysis and Visualization

in Translational Pharmacology

Shaodong Li
Jiandong Fei
Bo Shao
Zhenhua Kang
Guoqiang Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1509259

Brief Research Report

Published on 31 Jan 2025

Metformin dosage and galectin-3 levels: insights from PCOS patients preparing for IVF

in Translational Pharmacology

Valentina N. Nikolić
Milan Stefanović
Dejan Mitić
Slavica Sunarić
Vladana Stojiljkovic
Hristina Trajković
Aleksandra Ignjatović
Dragana Stokanović

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505022

434 views

Review

Accepted on 27 Jan 2025

Muscle Loss in Cancer Cachexia: what is the basis for nutritional support?

in Translational Pharmacology

Jaline Faiad
Márcia Fábia Andrade
Gabriela Salim de Castro
Marina Coelho
Giovana Aquino
Joyce Resende
Marilia Seelaender

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519278

Mini Review

Published on 22 Jan 2025

Brief summary of the regulatory frameworks of regenerative medicine therapies

in Translational Pharmacology

Jinah Yoon
Sukhyang Lee
Min Jung Kim
Jung-Hyun Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1486812

585 views

Brief Research Report

Published on 16 Jan 2025

Impact of using time-averaged exposure metrics on binary endpoints in exposure-response analyses

in Translational Pharmacology

Yu-Wei Lin
Anna Largajolli
A. Yin Edwards
S. Y. Amy Cheung
Kashyap Patel
Stefanie Hennig

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1487062

546 views

Original Research

Published on 09 Jan 2025

Targeted lipidomics analysis of possible molecular mechanisms of lipid changes in temporal lobe epilepsy models

in Translational Pharmacology

Huaiyu Sun
Xuewei Li
Zhiqing Chen
Hongmei Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1531524

520 views

Navigation group

Articles

Sodium nitrate regulates senescence accompanied by aortic atherosclerosis in ApoE -/-mice through the miR-34a/FGF-21 axis

Male Mice Treated with Combined Anti-Fibrotic Therapeutics, IPW5371 and Tadalafil, are Predisposed to Adverse Cardiovascular Events

A double-layer PLGA/CoI-MeHA tissue engineering scaffold for urethral reconstruction

The Adjunctive Role of Metformin in Patients with Mild to Moderate Ulcerative Colitis: A Randomized Controlled Study

Exploring the application of metal-based photothermal agents in photothermal therapy combined with immune checkpoint therapy

Potential effects of lipid lowering and antioxidant activity of exosomes from Phascolosoma esculenta: In vivo and in vitro Studies

Digital twin-enhanced three-organ microphysiological system for studying drug pharmacokinetics in pregnant women

Advances in hydrogel for diagnosis and treatment for Parkinson’s disease

SysNatMed: rational natural medicine discovery by systems genetics

Sex Differences in Metabolic Regulation by Gi/o-coupled Receptor Modulation of Exocytosis

Knowledge Structure and Dynamic Evolution of Nanomedicine in Liver Cancer Research: A Scientometric Analysis and Visualization

Metformin dosage and galectin-3 levels: insights from PCOS patients preparing for IVF

Muscle Loss in Cancer Cachexia: what is the basis for nutritional support?

Brief summary of the regulatory frameworks of regenerative medicine therapies

Impact of using time-averaged exposure metrics on binary endpoints in exposure-response analyses

Targeted lipidomics analysis of possible molecular mechanisms of lipid changes in temporal lobe epilepsy models