Original Research

Published on 04 Jun 2024

Influence of β-lactam pharmacodynamics on the systems microbiology of gram-positive and gram-negative polymicrobial communities

in Pharmacology of Infectious Diseases

Nicholas M. Smith
Harpreet Kaur
Ravneet Kaur
Trisha Minoza
Michael Kent
Ayeh Barekat
Justin R. Lenhard

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1339858

503 views

Original Research

Published on 30 May 2024

Targeting Leishmania infantum Mannosyl-oligosaccharide glucosidase with natural products: potential pH-dependent inhibition explored through computer-aided drug design

in Pharmacology of Infectious Diseases

Luis Daniel Goyzueta-Mamani
Haruna Luz Barazorda-Ccahuana
Mayron Antonio Candia-Puma
Alexsandro Sobreira Galdino
Ricardo Andrez Machado-de-Avila
Rodolfo Cordeiro Giunchetti
José L. Medina-Franco
Mónica Florin-Christensen
Eduardo Antonio Ferraz Coelho
Miguel Angel Chávez-Fumagalli

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1403203

1,636 views

Original Research

Published on 30 May 2024

Identification of urine biomarkers predictive of prolonged QTc interval in multidrug-resistant tuberculosis patients treated with bedaquiline

in Pharmacology of Infectious Diseases

Jiajia Yu
Weicong Ren
Jinfeng Yuan
Rongmei Liu
Liping Ma
Shenjie Tang
Yu Pang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1362544

772 views

Systematic Review

Published on 27 May 2024

Therapeutic effects of vitamin D supplementation on COVID-19 aggravation: a systematic review and meta-analysis of randomized controlled trials

in Pharmacology of Infectious Diseases

Yiyuan Yang
Wanli Sun
Fan Yang
Guoxia Zhang
Xinye Li
Shipeng Sun
Yanwei Xing

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1367686

1,562 views

Review

Published on 20 May 2024

Endolysins: a new antimicrobial agent against antimicrobial resistance. Strategies and opportunities in overcoming the challenges of endolysins against Gram-negative bacteria

in Pharmacology of Infectious Diseases

Fazal Mehmood Khan
Fazal Rasheed
Yunlan Yang
Bin Liu
Rui Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1385261

3,015 views
3 citations

Original Research

Published on 10 May 2024

Population pharmacokinetics, dosing optimization and clinical outcomes of biapenem in patients with sepsis

in Pharmacology of Infectious Diseases

Dayu Chen
Xuanyu Wu
Haixia Zhang
Huimin Yao
Lu Jin
Xuemei Luo
Jinchun Liu
Zejun Wu
Yuanchen Li
Wei Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1388150

955 views

Original Research

Published on 09 May 2024

Safety and efficacy evaluation of halicin as an effective drug for inhibiting intestinal infections

in Pharmacology of Infectious Diseases

Maolu Zhang
Shuqian Lin
Lianquan Han
Jiaming Zhang
Shaoning Liu
Xiuzhen Yang
Ruiming Wang
Xiaohui Yang
Yunpeng Yi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1389293

1,705 views

Editorial

Published on 07 May 2024

Editorial: Combinational therapy and nanotechnologies in combating pathogenic microbes and antibiotic resistance

in Pharmacology of Infectious Diseases

Kwang-sun Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1406043

503 views

Original Research

Published on 01 May 2024

Comparative efficacy of buparvaquone and imidocarb in inhibiting the in vitro growth of Babesia bovis

in Pharmacology of Infectious Diseases

Natalia M. Cardillo
Paul A. Lacy
Nicolas F. Villarino
J. Stone Doggett
Michael K. Riscoe
Reginaldo G. Bastos
Jacob M. Laughery
Massaro W. Ueti
Carlos E. Suarez

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1407548

1,155 views

Original Research

Published on 19 Apr 2024

Two promising Bacillus-derived antifungal lipopeptide leads AF4 and AF5 and their combined effect with fluconazole on the in vitro Candida glabrata biofilms

in Pharmacology of Infectious Diseases

Madduri Madhuri
Shivaprakash M. Rudramurthy
Utpal Roy

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1334419

890 views

Original Research

Published on 11 Apr 2024

In vitro pharmacokinetics/pharmacodynamics of FL058 (a novel beta-lactamase inhibitor) combined with meropenem against carbapenemase-producing Enterobacterales

in Pharmacology of Infectious Diseases

Zhiwei Huang
Xingchen Bian
Yi Li
Jiali Hu
Beining Guo
Xinyi Yang
Yi Jin
Shansong Zheng
Xinmei Wang
Cong Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1282480

818 views

Original Research

Published on 10 Apr 2024

Physalin H, physalin B, and isophysalin B suppress the quorum-sensing function of Staphylococcus aureus by binding to AgrA

in Pharmacology of Infectious Diseases

Junpei Yamaguchi
Teruhisa Manome
Yasumasa Hara
Yuriko Yamazaki
Yuumi Nakamura
Masami Ishibashi
Akiko Takaya

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1365815

1,064 views

Original Research

Published on 09 Apr 2024

Phage-antibiotic combinations in various treatment modalities to manage MRSA infections

in Pharmacology of Infectious Diseases

Archana Loganathan
Bulent Bozdogan
Prasanth Manohar
Ramesh Nachimuthu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1356179

2,436 views
3 citations

Review

Published on 02 Apr 2024

Inhibitory effect of natural compounds on quorum sensing system in Pseudomonas aeruginosa: a helpful promise for managing biofilm community

in Pharmacology of Infectious Diseases

Aref Shariati
Milad Noei
Marzieh Askarinia
Amin Khoshbayan
Abbas Farahani
Zahra Chegini

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1350391

2,637 views
3 citations

Original Research

Published on 21 Mar 2024

The synergistic antibacterial activity and mechanism of colistin-oxethazaine combination against gram-negative pathogens

in Pharmacology of Infectious Diseases

Jie Li
Ning Han
Yangyang Li
Feifei Zhao
Wenguang Xiong
Zhenling Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1363441

1,138 views
1 citation

Original Research

Published on 20 Mar 2024

Evaluating cardiac disorders associated with triazole antifungal agents based on the US Food and Drug Administration Adverse Event reporting system database

in Pharmacology of Infectious Diseases

Jinhua Chen
Shijun Xu
Weijiang Yu
Cuicui Sun
Wenzhou Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1255918

1,955 views

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Articles

Influence of β-lactam pharmacodynamics on the systems microbiology of gram-positive and gram-negative polymicrobial communities

Targeting Leishmania infantum Mannosyl-oligosaccharide glucosidase with natural products: potential pH-dependent inhibition explored through computer-aided drug design

Identification of urine biomarkers predictive of prolonged QTc interval in multidrug-resistant tuberculosis patients treated with bedaquiline

Therapeutic effects of vitamin D supplementation on COVID-19 aggravation: a systematic review and meta-analysis of randomized controlled trials

Endolysins: a new antimicrobial agent against antimicrobial resistance. Strategies and opportunities in overcoming the challenges of endolysins against Gram-negative bacteria

Population pharmacokinetics, dosing optimization and clinical outcomes of biapenem in patients with sepsis

Safety and efficacy evaluation of halicin as an effective drug for inhibiting intestinal infections

Editorial: Combinational therapy and nanotechnologies in combating pathogenic microbes and antibiotic resistance

Comparative efficacy of buparvaquone and imidocarb in inhibiting the in vitro growth of Babesia bovis

Two promising Bacillus-derived antifungal lipopeptide leads AF4 and AF5 and their combined effect with fluconazole on the in vitro Candida glabrata biofilms

In vitro pharmacokinetics/pharmacodynamics of FL058 (a novel beta-lactamase inhibitor) combined with meropenem against carbapenemase-producing Enterobacterales

Physalin H, physalin B, and isophysalin B suppress the quorum-sensing function of Staphylococcus aureus by binding to AgrA

Phage-antibiotic combinations in various treatment modalities to manage MRSA infections

Inhibitory effect of natural compounds on quorum sensing system in Pseudomonas aeruginosa: a helpful promise for managing biofilm community

The synergistic antibacterial activity and mechanism of colistin-oxethazaine combination against gram-negative pathogens

Evaluating cardiac disorders associated with triazole antifungal agents based on the US Food and Drug Administration Adverse Event reporting system database