Frontiers in Pharmacology | Pharmacology of Anti-Cancer Drugs

Original Research

Published on 17 Apr 2025

LINC01559 drives osimertinib resistance in NSCLC through a ceRNA network regulating miR-320a/IGF2BP3 axis

in Pharmacology of Anti-Cancer Drugs

Leidi Xu
Yibo Zhang
Liangliang Xing
Ying Zhou
Ning Chang
Hangtian Xi
Xiangrui Xu
Jian Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592846

114 views

Original Research

Published on 17 Apr 2025

Targeting PCNA/PARP1 axis inhibits the malignant progression of hepatocellular carcinoma

in Pharmacology of Anti-Cancer Drugs

Jipin Li
Tao Yong
Yali Chen
Tingyu Zeng
Kaifeng Zhang
Shuping Wang
Youcheng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571786

Systematic Review

Accepted on 16 Apr 2025

Efficacy and safety of neoadjuvant PD-1 inhibitors or PD-L1 inhibitors combined with chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis

in Pharmacology of Anti-Cancer Drugs

Jiaojiao Yu
Hua Zhu
Mingxu Li
Xiaoxia Tang
Ke Luan
Yinhuan Zhi
Shan Yin
Yuanqi Su
Jingyan Long
Jieru Quan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570467

Review

Published on 16 Apr 2025

SREBP2 as a central player in cancer progression: potential for targeted therapeutics

in Pharmacology of Anti-Cancer Drugs

Ruiqi Chen
Tianyu Chen
Xiang Li
Junfeng Yu
Min Lin
Siqi Wen
Man Zhang
Jinchi Chen
Bei Yi
Huage Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1535691

142 views

Original Research

Published on 16 Apr 2025

SUMOylation substrate encoding genes as prognostic biomarkers in pancreatic ductal adenocarcinoma with functional assessment of SAF-B2

in Pharmacology of Anti-Cancer Drugs

Xiangjun Wang
Chuanxin Yang
Yangming Liu
Jian Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532658

145 views

Editorial

Published on 16 Apr 2025

Editorial: Multi-omics application in exploring potential biomarkers targeting resistance of anti-cancer drugs

in Pharmacology of Anti-Cancer Drugs

Huan Wang
Jindong Xie
Zhi Tian
Diane S. Allen-Gipson
Hailin Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1594064

186 views

Original Research

Published on 16 Apr 2025

Synthesis of a novel mitochondrial fluorescent probe - killing cancer cells in vitro and in vivo

in Pharmacology of Anti-Cancer Drugs

Xiaowen Yang
Yiting Zhan
Yifei Li
Xinzhuang Shen
Yuqiu Ma
Zongjun Liu
Yipeng Liu
Chengjin Liang
Xiaoyuan Zhang
Yehao Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1543559

215 views

Editorial

Published on 16 Apr 2025

Editorial: Autophagy and lung cancer therapy: targeted drug development and new emerging technology

in Pharmacology of Anti-Cancer Drugs

Ming Zhang
Yu Wang
Chunhui Yang
Xin You
Yafei Feng
Xianglin Yang
Qi Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1599548

200 views

Original Research

Accepted on 15 Apr 2025

IL6/CCL2 from M2 polarized microglia promotes breast cancer brain metastasis and the reversal effect of β-elemene

in Pharmacology of Anti-Cancer Drugs

Rong-Rong Zhang
Qian Feng
Cai-Zhi Li
Yi-Hua Zou
Xue-Yu Wang
Xia Yang
Rong Zhang
Zhong-qiu Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1547333

Original Research

Accepted on 15 Apr 2025

Bioinformatics Analysis Across Pan-Cancer and Experimental Validation in Hepatocellular Carcinoma Revealed the Oncogenic Role of SF3B6

in Pharmacology of Anti-Cancer Drugs

Linshuang Tu
Jiefu Luo
Ya Yin
Huihong Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516534

Original Research

Published on 15 Apr 2025

Multiscale screening and identifying specific targets for artesunate in suppressing bladder cancer

in Pharmacology of Anti-Cancer Drugs

Yi Yuan
Guangdi Chu
Qingyue Ma
Zhijuan Liang
Ye Liang
Haitao Niu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584502

170 views

Review

Published on 15 Apr 2025

Parthenolide: pioneering new frontiers in hematological malignancies

in Pharmacology of Anti-Cancer Drugs

Elmira Zarei
Ayda Zarei
Azadeh Omidkhoda

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534686

193 views

Case Report

Published on 15 Apr 2025

Case Report: Neoadjuvant therapy with ripretinib for gastrointestinal stromal tumor: a case report

in Pharmacology of Anti-Cancer Drugs

Guanmo Liu
Zicheng Zheng
Jie Li
Yixuan He
Chenggang Zhang
Yihua Wang
Weiming Kang
Xin Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573610

168 views

Original Research

Published on 15 Apr 2025

Integrative analysis of m6A-SNPs and single-cell RNA sequencing reveals key drivers of endocrine combined with CDK4/6 inhibitor therapy resistance in ER+ breast cancer

in Pharmacology of Anti-Cancer Drugs

Ruijie Ming
Han Zhang
Huan Wu
Fangbiao Zhan
Xiaoping Huang
Huawen Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1590363

165 views

Original Research

Published on 14 Apr 2025

Dehydroleucodine exerts an antiproliferative effect on human Burkitt’s lymphoma Daudi cells via SLC7A11-mediated ferroptosis

in Pharmacology of Anti-Cancer Drugs

Rui Shen
Fang Cheng
Rui Guo
Wenjing Wang
Xiaolong Yang
Yemiao Chen
Yaokai Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572364

177 views

Case Report

Published on 14 Apr 2025

Case Report: A novel ELMOD3-ALK and EML4-ALK double-fusion responses to neoadjuvant alectinib in a lung adenocarcinoma patient

in Pharmacology of Anti-Cancer Drugs

Kaili Huang
Wen Li
Yinyin Xue
Lei Peng
Qiang Wu
Qinghua Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1515826

217 views