Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Mini Review

Published on 12 Feb 2025

Association between CYP2C19 polymorphism and proton pump inhibitors adverse drug reactions: a narrative review

in Pharmacogenetics and Pharmacogenomics

Asmaa Ibrahim
Kazeem Yusuff
Ahmed Awaisu
Hazem Elewa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1523399

125 views

Mini Review

Accepted on 11 Feb 2025

Precision Medicine in Colorectal Cancer: Genomics Profiling and Targeted Treatment

in Pharmacogenetics and Pharmacogenomics

Rony Abdi Syahputra
Adi Muradi Muhar
Adrian Velaro
Arya Tjipta Prananda
Sony Eka Nugraha
Princella Halim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532971

Original Research

Accepted on 03 Feb 2025

The CYP2D6 Phenotyping Performance of Single-point Saliva Metabolic Ratio in a Healthy

in Pharmacogenetics and Pharmacogenomics

Yongfa Huang
Zhangyuting He
Xiaoduo Guan
Pei Hu
Rui Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1438760

Review

Accepted on 03 Feb 2025

Genome-wide Functional Annotation of Variants: A Systematic Review of State-of-the-Art Tools, Techniques and Resources

in Pharmacogenetics and Pharmacogenomics

Eleftherios Pilalis
Dimitrios Zisis
Christina Andrinopoulou
Theodora Karamanidou
Maria Antonara
Thanos G. Stavropoulos
Aristotelis Chatziioannou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1474026

Original Research

Published on 03 Feb 2025

Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses

in Pharmacogenetics and Pharmacogenomics

Kohen Goble
Aarav Mehta
Damien Guilbaud
Jacob Fessler
Jingting Chen
William Nenad
Christina G. Ford
Oliver Cope
Darby Cheng
William Dennis

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516621

257 views

Original Research

Published on 30 Jan 2025

Deciphering the heterogeneity and plasticity of the tumor microenvironment in liver cancer provides insights for prognosis

in Pharmacogenetics and Pharmacogenomics

Yihao Sun
Guojuan Shi
Jian Yang
Chun-Zhong Zhou
Chuhan Peng
Yu-Hong Luo
Ying Pan
Rui-Qi Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1495280

264 views

Review

Published on 29 Jan 2025

Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications

in Pharmacogenetics and Pharmacogenomics

Zhenglin He
Yishuo Ji
Yutong Yuan
Tianfang Liang
Chenglin Liu
Yiping Jiao
Yimeng Chen
Yiming Yang
Liang Han
Yue Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532558

415 views

Original Research

Published on 22 Jan 2025

Better understanding the phenotypic effects of drugs through shared targets in genetic disease networks

in Pharmacogenetics and Pharmacogenomics

Elena Díaz-Santiago
Aurelio A. Moya-García
Jesús Pérez-García
Raquel Yahyaoui
Christine Orengo
Florencio Pazos
James R. Perkins
Juan A. G. Ranea

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1470931

557 views

Original Research

Published on 07 Jan 2025

Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients

in Pharmacogenetics and Pharmacogenomics

Yanping Guan
Bilian Li
Yiyu Zhang
Hao Luo
Xueding Wang
Xue Bai
Zhuoling Zheng
Yaying Huang
Wei Wei
Min Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1515523

454 views

Editorial

Published on 03 Jan 2025

Editorial: Insights in pharmacogenetics and pharmacogenomics: 2023

in Pharmacogenetics and Pharmacogenomics

José A. G. Agúndez
Elena García-Martín

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1540478

265 views

Original Research

Published on 03 Jan 2025

Exploring perceived barriers and attitudes in young adults towards antidepressant pharmacotherapy, including the implementation of pharmacogenetic testing to optimize prescription practices

in Pharmacogenetics and Pharmacogenomics

Bradley Roberts
Zahra Cooper
Georgia Landery
Susanne Stanley
Bernadette T. Majda
Khan R. L. Collins
P. Anthony Akkari
Sean D. Hood
Jennifer Rodger

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1526101

504 views

Original Research

Accepted on 23 Dec 2024

Allele and genotype frequencies of variants in P450 cytochromes, transports and DNA repair enzymes in the Dominican Republic population

in Pharmacogenetics and Pharmacogenomics

Elizabeth Pérez-Duval
Berniza Calderón
Marlen Izquierdo
José Alfredo Herrera Isidrón
Elizabeth Reyes Reyes
Alejandro Herrera
Manuel Soto
Alba Beltré
Idania Rodeiro

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494482

Original Research

Published on 20 Dec 2024

Integration of pharmacogenetic data in epic genomic module drives clinical decision support alerts

in Pharmacogenetics and Pharmacogenomics

Kimberly J. Newsom
Bradley Hall
Katherine A. Martinez
Scott Nelson
Petr Starostik
Khoa Nguyen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1458095

1,300 views

Review

Published on 20 Dec 2024

Pharmacogenomics for neurodegenerative disorders - a focused review

in Pharmacogenetics and Pharmacogenomics

S. Rehan Ahmad
Md. Zeyaullah
Mohammad Suhail Khan
Abdullah M. AlShahrani
Abdelrhman A. Galaleldin Altijani
Haroon Ali
Adam Dawria
Ali Mohieldin
Mohammad Shane Alam
Awad Osman Abdalla Mohamed

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1478964

1,244 views

Case Report

Published on 19 Dec 2024

Severe liver injury induced by minocycline in hepatitis B patient: a Case Report

in Pharmacogenetics and Pharmacogenomics

Ran Wang
Yun Li
Xue Xia

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516217

670 views

Review

Published on 16 Dec 2024

Pediatric flecainide pharmacogenomics: a roadmap to delivering precision-based care to pediatrics arrhythmias

in Pharmacogenetics and Pharmacogenomics

Ronald Palmen
Mollie Walton
Jonathan Wagner

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1477485

529 views

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Articles

Association between CYP2C19 polymorphism and proton pump inhibitors adverse drug reactions: a narrative review

Precision Medicine in Colorectal Cancer: Genomics Profiling and Targeted Treatment

The CYP2D6 Phenotyping Performance of Single-point Saliva Metabolic Ratio in a Healthy

Genome-wide Functional Annotation of Variants: A Systematic Review of State-of-the-Art Tools, Techniques and Resources

Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses

Deciphering the heterogeneity and plasticity of the tumor microenvironment in liver cancer provides insights for prognosis

Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications

Better understanding the phenotypic effects of drugs through shared targets in genetic disease networks

Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients

Editorial: Insights in pharmacogenetics and pharmacogenomics: 2023

Exploring perceived barriers and attitudes in young adults towards antidepressant pharmacotherapy, including the implementation of pharmacogenetic testing to optimize prescription practices

Allele and genotype frequencies of variants in P450 cytochromes, transports and DNA repair enzymes in the Dominican Republic population

Integration of pharmacogenetic data in epic genomic module drives clinical decision support alerts

Pharmacogenomics for neurodegenerative disorders - a focused review

Severe liver injury induced by minocycline in hepatitis B patient: a Case Report

Pediatric flecainide pharmacogenomics: a roadmap to delivering precision-based care to pediatrics arrhythmias