Frontiers in Pharmacology | Neuropharmacology

Systematic Review

Accepted on 14 Mar 2025

Effect and safety of perioperative ketamine/esketamine administration on postoperative pain and depression after breast cancer surgery: a systematic review and meta-analysis

in Neuropharmacology

Xinyi Sun
Chengwei Li
Lin Xu
Xiaojie Lin
Zheng Zhang
Chunlong Lin
Jianjun Li
Penghui Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532524

Systematic Review

Accepted on 14 Mar 2025

Effects of natural extracts in cognitive function of healthy adults : A systematic review and network meta-analysis

in Neuropharmacology

Zhi-yuan Wang
Yalu Deng
Tingyuan Zhou
Yi Liu
Yu Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573034

Original Research

Published on 14 Mar 2025

Evaluation of the neuroprotective potential of benzylidene digoxin 15 against oxidative stress in a neuroinflammation models induced by lipopolysaccharide and on neuronal differentiation of hippocampal neural precursor cells

in Neuropharmacology

Gilvânia A. Cordeiro
Jessica A. Faria
Leticia Pavan
Israel J. P. Garcia
Eduarda P. F. I. Neves
Gustavo Fernando de Frazao Lima
Hericles M. Campos
Pâmela Y. Ferreira
Paulo C. Ghedini
Elisa M. Kawamoto

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537720

195 views

Review

Published on 14 Mar 2025

The critical role of Sirt1 in ischemic stroke

in Neuropharmacology

Ziyi Jia
Ke Xu
Ruobing Li
Siyu Yang
Long Chen
Qianwen Zhang
Shulin Li
Xiaowei Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1425560

Original Research

Published on 13 Mar 2025

A real-world safety surveillance study of aducanumab through the FDA adverse event reporting system

in Neuropharmacology

Jingjing Huang
Xiaohong Long
Chunyong Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1522058

213 views

Review

Published on 13 Mar 2025

Crosstalk between neuroinflammation and ferroptosis: Implications for Parkinson’s disease progression

in Neuropharmacology

Xiangyu Guo
Ran Wei
Xunzhe Yin
Ge Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528538

121 views

Original Research

Published on 13 Mar 2025

Randomized crossover clinical studies to assess abuse liability and nicotine pharmacokinetics of Velo Oral Nicotine pouches

in Neuropharmacology

Milly N. Kanobe
Christie Y. Powell
Makena Patrudu
Sarah A. Baxter
Melissa A. Tapia
John Darnell
Kristen Prevette
Alison G. Gibson
Sarah A. Ayoku
Leanne Campbell

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1547073

522 views

Original Research

Published on 12 Mar 2025

Vortioxetine alleviates motor, cognitive and emotional disorders in post-stroke rats by regulating the TLR-2/NF-κB pathway

in Neuropharmacology

Ziqiang Dong
Zhihui Dong
Lili Xu
Jinfeng Zhang
Lin Li
Rongjuan Wang
Xiaoyan Huang
Zhengqiang Zou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555079

184 views

Original Research

Published on 12 Mar 2025

Assessing the effects of antidepressant use on stroke recurrence and related outcomes in ischemic stroke patients: a propensity score matched analysis

in Neuropharmacology

Faisal F. Alamri
Daniyah A. Almarghalani
Yasser Alatawi
Eman A. Alraddadi
Omar Babateen
Ahmed Alayyafi
Ziyad Almalki
Khaled Alsalhi
Khaled Alzahrani
Ahmed Alghamdi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558703

242 views

Original Research

Published on 11 Mar 2025

Zingerone alleviates inflammatory pain by reducing the intrinsic excitability of anterior cingulate cortex neurons in a mice model

in Neuropharmacology

Yuanyuan Wang
Lang Dong
Shu Han
Yuehan You
Mingrui Zhang
Bingjing Sun
Hong Ni
Rongjing Ge
Jianhong Liu
Jiandong Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1543594

208 views

Original Research

Accepted on 10 Mar 2025

Brosimine B and the Biphasic Dose-Response: Insights into Hormesis and Retinal Neuroprotection

in Neuropharmacology

Susanne Suely Santos da Fonseca
Natacha Medeiros de Souza Port's
Gisele Priscila Soares de Aguiar
Eliã Pinheiro Botelho
Nádia Miléo Garcês de Couto
Wandson Braamcamp de Souza Pinheiro
André Salim Khayat
Elizabeth Sumi Yamada
Edmar Tavares da Costa
Chubert Bernardo Castro de Sena

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558726

Review

Accepted on 10 Mar 2025

Natural products protect against spinal cord injury by inhibiting ferroptosis: A literature review

in Neuropharmacology

Wei She
Su Junxiao
Wenji Ma
Guohai Ma
Jianfu Li
Hui Zhang
Cheng Qiu
Xingyong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557133

Original Research

Published on 07 Mar 2025

α-Bisabolol alleviates doxorubicin-induced cognitive dysfunction in rats via enhancing the hippocampal BDNF/TrKB signaling and inhibiting neuroinflammation

in Neuropharmacology

Sara T. Elazab
Walter H. Hsu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549009

241 views

Systematic Review

Accepted on 06 Mar 2025

Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a systematic review and network meta-analysis

in Neuropharmacology

Long-yun Zhou
Xiaobo Wang
Xu-qing Chen
Ran Li
Bin-Bin Yu
Meng-Xiao Pan
Lu Fang
Jian Li
Xue-Jun Cui
Min Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538879

Original Research

Accepted on 06 Mar 2025

Indole-3-acetic acid and chenodeoxycholic acid attenuate TLR4/NF-κB signaling and endoplasmic reticulum stress in valproic acid-induced neurotoxicity

in Neuropharmacology

Wedad S Sarawi
Ahlam Mohammed Alhusaini
Ghada S Barwaished
Myasah M Altamimi
Iman H Hasan
Amjad S Aljarboa
Norah K Algarzae
Saleh A Bakheet
Samiah A Alhabardi
Sheikh F Ahmad

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570125

Systematic Review

Published on 06 Mar 2025

Clinical implications of fracture severity risk with pioglitazone: a systematic review and meta-analysis of clinical randomized trials

in Neuropharmacology

Hala F. Azhari
Jesse Dawson

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1357309

184 views

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Articles

Effect and safety of perioperative ketamine/esketamine administration on postoperative pain and depression after breast cancer surgery: a systematic review and meta-analysis

Effects of natural extracts in cognitive function of healthy adults : A systematic review and network meta-analysis

Evaluation of the neuroprotective potential of benzylidene digoxin 15 against oxidative stress in a neuroinflammation models induced by lipopolysaccharide and on neuronal differentiation of hippocampal neural precursor cells

The critical role of Sirt1 in ischemic stroke

A real-world safety surveillance study of aducanumab through the FDA adverse event reporting system

Crosstalk between neuroinflammation and ferroptosis: Implications for Parkinson’s disease progression

Randomized crossover clinical studies to assess abuse liability and nicotine pharmacokinetics of Velo Oral Nicotine pouches

Vortioxetine alleviates motor, cognitive and emotional disorders in post-stroke rats by regulating the TLR-2/NF-κB pathway

Assessing the effects of antidepressant use on stroke recurrence and related outcomes in ischemic stroke patients: a propensity score matched analysis

Zingerone alleviates inflammatory pain by reducing the intrinsic excitability of anterior cingulate cortex neurons in a mice model

Brosimine B and the Biphasic Dose-Response: Insights into Hormesis and Retinal Neuroprotection

Natural products protect against spinal cord injury by inhibiting ferroptosis: A literature review

α-Bisabolol alleviates doxorubicin-induced cognitive dysfunction in rats via enhancing the hippocampal BDNF/TrKB signaling and inhibiting neuroinflammation

Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a systematic review and network meta-analysis

Indole-3-acetic acid and chenodeoxycholic acid attenuate TLR4/NF-κB signaling and endoplasmic reticulum stress in valproic acid-induced neurotoxicity

Clinical implications of fracture severity risk with pioglitazone: a systematic review and meta-analysis of clinical randomized trials