Frontiers in Pharmacology | Inflammation Pharmacology

Original Research

Published on 13 Mar 2025

Mechanism of nimodipine in treating neurodegenerative diseases: in silico target identification and molecular dynamic simulation

in Inflammation Pharmacology

Shuang Zheng
Yin Wang
Shuainan Tang
Yuntao Guo
Duan Ma
Xin Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549953

Original Research

Published on 12 Mar 2025

Deciphering the role of IGFBP5 in delaying fibrosis and sarcopenia in aging skeletal muscle: therapeutic implications and molecular mechanisms

in Inflammation Pharmacology

Luze Shi
Zheci Ding
Jiwu Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557703

144 views

Mini Review

Published on 12 Mar 2025

Salt-sensitive hypertension: role of endothelial and vascular dysfunction and sex

in Inflammation Pharmacology

Helen M. Butler
Marice K. McCrorey
Lada Palygina
Ryan Lacey
Justin P. Van Beusecum

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565962

Brief Research Report

Published on 07 Mar 2025

Efficacy and safety of conventional disease-modifying antirheumatic drugs in VEXAS syndrome: real-world data from the international AIDA network

in Inflammation Pharmacology

Antonio Vitale
Flavia Leone
Valeria Caggiano
Andrea Hinojosa-Azaola
Eduardo Martín-Nares
Guillermo Arturo Guaracha-Basañez
Jiram Torres-Ruiz
Perla Ayumi Kawakami-Campos
Pravin Hissaria
Alicia Callisto

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539756

271 views

Case Report

Published on 06 Mar 2025

Case report: Effectiveness of Janus kinase inhibitors in the management of isolated noninfectious uveitis: a case series

in Inflammation Pharmacology

Nina Vidic Krhlikar
Matija Tomšič
Polona Jaki Mekjavić
Pia Klobučar
Nataša Vidović Valentinčič

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1509404

195 views

Review

Accepted on 04 Mar 2025

Ferroptosis and Hyperoxic Lung Injury: Insights into Pathophysiology and Treatment Approaches

in Inflammation Pharmacology

Liu Qian
Xiaoqiong Zhou
Lei Tian
Wenyan Xiong
Yulan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568246

Original Research

Accepted on 04 Mar 2025

Phenylethyl Isothiocyanate Mitigates Drug-Induced Liver Injury in Mice by Inhibiting Hepatocyte Pyroptosis through the NLRP3-Caspase-1-GSDMD Pathway

in Inflammation Pharmacology

Ning An
XiaoRu Wang
Meng Cheng
Mei Bai
Jia Qin
jincai Cheng
Qiang Xu
Xuefeng Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539934

Original Research

Published on 04 Mar 2025

Aspirin is associated with improved 30-day mortality in patients with sepsis-associated liver injury: a retrospective cohort study based on MIMIC IV database

in Inflammation Pharmacology

Jianbao Wang
Xuemei Hu
Susu Cao
Yiwen Zhao
Mengting Chen
Tianfeng Hua
Min Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1514392

229 views

Review

Accepted on 03 Mar 2025

Cell Death In Acute Lung Injury: caspase-regulated apoptosis, pyroptosis, necroptosis, and PANoptosis

in Inflammation Pharmacology

Jun Xiao
Wang Lichuan
Bohan Zhang
Ana Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559659

Original Research

Accepted on 03 Mar 2025

Senecio scandens Buch.-Ham. polysaccharides exert anti-atopic dermatitis properties by modulating gut microbiota and MAPK/NF-κB pathway

in Inflammation Pharmacology

Zhi-Qin Hu
Shu-Shu Xie
Ming-Yuan Zhou
Yu-Chi Chen
Fang-Mei Zhou
Zhi-Shan Ding
Xiao-Qing Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573135

Mini Review

Accepted on 03 Mar 2025

Interplay Between Endogenous hormones and Immune Systems in Human Metapneumovirus Pathogenesis and Management

in Inflammation Pharmacology

Viviana A. Ruiz-Pozo
Santiago Cadena-Ullauri
Rafael Tamayo-Trujillo
Patricia Guevara- Ramírez
Elius Andrés Paz Cruz
Mayra A Castañeda Cataña
Ana Karina Zambrano

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568828

Original Research

Accepted on 03 Mar 2025

Effect of an anti-interleukin-5 antibody on development of vasculitis in an ovalbumin-induced eosinophilic vasculitis mouse model

in Inflammation Pharmacology

Kiyoto Kageyama
Eri Kikuchi
Nao Hoshino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546785

Review

Published on 03 Mar 2025

Inflammation pathways as therapeutic targets in angiotensin II induced atrial fibrillation

in Inflammation Pharmacology

Ailin Hou
Dazhuo Shi
Hongbo Huang
Yuxuan Liu
Ying Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1515864

282 views

Original Research

Published on 28 Feb 2025

Identification of glycolysis-related gene signatures for prognosis and therapeutic targeting in idiopathic pulmonary fibrosis

in Inflammation Pharmacology

Han Gao
Zhongyi Sun
Xingxing Hu
Weiwei Song
Yuan Liu
Menglin Zou
Minghui Zhu
Zhenshun Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1486357

194 views

Original Research

Accepted on 27 Feb 2025

Homoplantaginin exerts therapeutic effects on intervertebral disc degeneration by alleviating TNF-αinduced nucleus pulposus cell senescence and inflammation

in Inflammation Pharmacology

Jiadong Guo
Pu Zhang
Xiao Yang
Xin Wang
Xiankun Cao
Jie Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1526107

Original Research

Published on 27 Feb 2025

Unfractionated heparin may improve near-term survival in patients admitted to the ICU with sepsis attributed to pneumonia: an observational study using the MIMIC-IV database

in Inflammation Pharmacology

Shusheng Fang
Yali Wang
Wenyu Nan
Yanhao Feng
Wen Su
Yiming Wang
Xiaodong Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1518716

299 views

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Articles

Mechanism of nimodipine in treating neurodegenerative diseases: in silico target identification and molecular dynamic simulation

Deciphering the role of IGFBP5 in delaying fibrosis and sarcopenia in aging skeletal muscle: therapeutic implications and molecular mechanisms

Salt-sensitive hypertension: role of endothelial and vascular dysfunction and sex

Efficacy and safety of conventional disease-modifying antirheumatic drugs in VEXAS syndrome: real-world data from the international AIDA network

Case report: Effectiveness of Janus kinase inhibitors in the management of isolated noninfectious uveitis: a case series

Ferroptosis and Hyperoxic Lung Injury: Insights into Pathophysiology and Treatment Approaches

Phenylethyl Isothiocyanate Mitigates Drug-Induced Liver Injury in Mice by Inhibiting Hepatocyte Pyroptosis through the NLRP3-Caspase-1-GSDMD Pathway

Aspirin is associated with improved 30-day mortality in patients with sepsis-associated liver injury: a retrospective cohort study based on MIMIC IV database

Cell Death In Acute Lung Injury: caspase-regulated apoptosis, pyroptosis, necroptosis, and PANoptosis

Senecio scandens Buch.-Ham. polysaccharides exert anti-atopic dermatitis properties by modulating gut microbiota and MAPK/NF-κB pathway

Interplay Between Endogenous hormones and Immune Systems in Human Metapneumovirus Pathogenesis and Management

Effect of an anti-interleukin-5 antibody on development of vasculitis in an ovalbumin-induced eosinophilic vasculitis mouse model

Inflammation pathways as therapeutic targets in angiotensin II induced atrial fibrillation

Identification of glycolysis-related gene signatures for prognosis and therapeutic targeting in idiopathic pulmonary fibrosis

Homoplantaginin exerts therapeutic effects on intervertebral disc degeneration by alleviating TNF-αinduced nucleus pulposus cell senescence and inflammation

Unfractionated heparin may improve near-term survival in patients admitted to the ICU with sepsis attributed to pneumonia: an observational study using the MIMIC-IV database