Frontiers in Pharmacology | Gastrointestinal and Hepatic Pharmacology

Study Protocol

Accepted on 11 Jul 2025

Brucea javanica Oil Emulsion plus Supportive Care for Refractory Advanced Colorectal Cancer: A Pilot RCT Protocol

in Gastrointestinal and Hepatic Pharmacology

Liyuan Fang
Yan Wang
Yuhang Fang
Runxi Wang
Yi Xie
Shuhan Yang
Suying Liu
Ying Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610575

190 views

Systematic Review

Accepted on 11 Jul 2025

Potential of ciprofol as an alternative to propofol in elderly patients undergoing gastrointestinal endoscopy: a meta-analysis and trial sequential analysis

in Gastrointestinal and Hepatic Pharmacology

Juan Deng
Yunfeng Yu
Xinyu Yang
Yuman Yin
Min Liao
Zhenjie Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1644182

105 views

Original Research

Accepted on 11 Jul 2025

Exploring the Molecular Characteristics of Inflammatory Bowel Disease from the Perspective of Hypoxia-Related Genes

in Gastrointestinal and Hepatic Pharmacology

Lin Mou
Lei Zheng
Rui Chen
Yifei Wang
Niao Yu
Xueyan Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1612676

Review

Published on 11 Jul 2025

Beyond antibiotics: probiotics as a promising ally against Helicobacter pylori

in Gastrointestinal and Hepatic Pharmacology

Lin Yuan
Chong Yang
Ying Han
Fan Yang
Huabing Tu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1620870

1,101 views

Original Research

Published on 11 Jul 2025

Evaluating the risk of osteoporosis-related adverse events with proton pump inhibitors: a pharmacovigilance study

in Gastrointestinal and Hepatic Pharmacology

Jingkai Di
Nan Yang
Yicong Zhao
Shuai Chen
Zijian Guo
Dongdong He
Chuan Xiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1582908

248 views

Review

Published on 11 Jul 2025

Role of the Annexin A protein family in liver diseases: insights and therapeutic opportunities

in Gastrointestinal and Hepatic Pharmacology

Mingyang Feng
Yong He
Hui Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569927

253 views

Systematic Review

Published on 11 Jul 2025

What is the optimal biological therapy for moderate to severe ulcerative colitis: a systematic review and network meta-analysis

in Gastrointestinal and Hepatic Pharmacology

Longbin Huang
Chen Kong
Ningning Yue
Hailan Zhao
Yuan Zhang
Chengmei Tian
Zhiliang Mai
Daoru Wei
Ruiyue Shi
Jun Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1602024

932 views

Original Research

Published on 09 Jul 2025

D-glucaro-1,4-lactone alleviates acetaminophen-induced hepatotoxicity in mice via modulating gut microbiota and metabolites associated with Lactobacillus–glutamine and nicotinic acid pathways

in Gastrointestinal and Hepatic Pharmacology

Zhiying Song
Yiran Pan
Zeyu Wang
Yujing Chen
Yufeng Deng
Lele Wang
Qi Hu
Wenxiang Huang
Shuilin Sun
Baogang Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627850

325 views

Original Research

Published on 08 Jul 2025

Glucagon-like peptide-1 receptor agonist-induced cholecystitis and cholelithiasis: a real-world pharmacovigilance analysis using the FAERS database

in Gastrointestinal and Hepatic Pharmacology

Chao Tao
Yinhui Zhang
Tenggang Wan
Wenting Zhao
Jing Chen
Ke Wang
Liuxuan Yang
Guojun Wang
Qian Ding
Jinlu Shang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557691

412 views

Original Research

Accepted on 07 Jul 2025

Analyzing the potential targets and mechanisms of liver damage induced by Acetyl tributyl citrate (ATBC) plasticizer using network toxicology, molecular docking and in vitro experiments

in Gastrointestinal and Hepatic Pharmacology

Dong-qun Guo
Yu-Ming Fang
Zhen-dong Sun
Ya-fen Zeng
Gui-dan Wang
Jin-wei Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1636576

Original Research

Accepted on 04 Jul 2025

Hydrogen gas (H2) delivered by intraperitoneal injection alleviated methionine-and choline-deficient diet-induced metabolic dysfunctionassociated steatotic liver disease in mice via inhibiting GSDMD-and GSDME-mediated pyroptosis

in Gastrointestinal and Hepatic Pharmacology

Yun Chen
Kangrong Wang
Wenhai Guo
Chengqin Lu
Wenting Suo
Qiuling Li
Yao Deng
Xinling Chen
Min Dai
Xiaodong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1575106

187 views

Review

Accepted on 02 Jul 2025

The role of gallic acid in liver disease: A review of its phytochemistry, pharmacology, and safety

in Gastrointestinal and Hepatic Pharmacology

Xiaohan Zhai
Peiyu Li
Yifan Song
Lv Linlin
Wenshuo Zhang
Aixi Jia
Deshi Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1595508

135 views

Original Research

Published on 02 Jul 2025

Nimotuzumab plus chemotherapy and immunotherapy as first-line/neoadjuvant therapy for advanced esophageal squamous cell carcinoma

in Gastrointestinal and Hepatic Pharmacology

Qi Wang
Zhi Cui
Muhong Deng
Guoqing Zhang
Fangfang Jing
Yue Ma
Fang Pang
Quanli Han

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1585048

629 views

Original Research

Published on 30 Jun 2025

Pharmacological basis for medicinal use of Cymbopogon proximus Hochst. ex A. Rich. Essential oil in hyperactive gastrointestinal disorders

in Gastrointestinal and Hepatic Pharmacology

Hassan N. Althurwi
Najeeb Ur Rehman
Maged S. Abdel-Kader
Faisal F. Albaqami

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1533511

478 views

Systematic Review

Published on 26 Jun 2025

Effect of serum MMP-7 on the diagnostic accuracy of biliary atresia: systematic review and meta-analysis

in Gastrointestinal and Hepatic Pharmacology

Haojun Wang
Hui Liu
Wanfu Li
Ainiwaer Keranmu
Peng Liang
Yaqi Wang
Tao Zhang
Yeliaman Jiayilawu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1581053

614 views

Original Research

Published on 25 Jun 2025

Explore the changes of metabolites in feces and serum of acute pancreatitis patients with different etiologies by LC-MS based metabolomics strategy

in Gastrointestinal and Hepatic Pharmacology

Meng-Yan Cui
Miao-Yan Fan
Jun Wu
Su-Min Chen
Meng-Qi Zhao
Qiao-Li Jiang
Jing-Jing Wang
Yue Zeng
Yu Zhao
Ying-Ying Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1614713

528 views