Original Research

Published on 06 Nov 2024

Structure-guided drug repurposing identifies aristospan as a potential inhibitor of β-lactamase: insights from virtual screening and molecular dynamics simulations

in Experimental Pharmacology and Drug Discovery

Moyad Shahwan
Mohd Shahnawaz Khan
Azna Zuberi
Nojood Altwaijry
Anas Shamsi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1459822

270 views

Mini Review

Published on 06 Nov 2024

Recent advances in extracellular matrix manipulation for kidney organoid research

in Experimental Pharmacology and Drug Discovery

Ren Wang
Yufei Sui
Qiuyan Liu
Yucui Xiong
Shanshan Li
Wu Guo
Yiwei Xu
Sheng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1472361

177 views

Original Research

Published on 06 Nov 2024

Berberine ameliorates septic cardiomyopathy through protecting mitochondria and upregulating Notch1 signaling in cardiomyocytes

in Experimental Pharmacology and Drug Discovery

Qi Shen
Yufan Yuan
Zelin Li
Ying Ling
Jian Wang
Mingjing Gao
Peng Wang
Mengli Li
Lizhong Lai
Jinlan Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1502354

194 views

Original Research

Published on 06 Nov 2024

Yigu decoction regulates plasma miRNA in postmenopausal osteoporosis patients: a randomized controlled trial

in Experimental Pharmacology and Drug Discovery

Haifeng Chen
Ruikun Zhang
Guijin Li
Kun Yan
Ziqi Wu
Yang Zhang
Zhineng Chen
Xinmiao Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1460906

144 views

Original Research

Published on 05 Nov 2024

Exploring the mechanism of sesamin for the treatment of PM2.5-induced cardiomyocyte damage based on transcriptomics, network pharmacology and experimental verification

in Experimental Pharmacology and Drug Discovery

Yadong Zhang
Rui Wen
Jingyi Ren
Fan Zhang
Huanting Pei
Jinshi Zuo
Yuxia Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1486563

246 views

Review

Accepted on 04 Nov 2024

Pathologic function and therapeutic potential of extracellular vesicle miRNA in sepsis

in Experimental Pharmacology and Drug Discovery

Rou Deng
Xiayu Cui
Runze Zhang
Changya Liu
Jielian Luo
Liang Liu
Wen Zhang
Bangjiang Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1452276

Review

Published on 01 Nov 2024

Advances of curcumin in nervous system diseases: the effect of regulating oxidative stress and clinical studies

in Experimental Pharmacology and Drug Discovery

Yuxun Wei
Hong Li
Yue Li
Yue Zeng
Tian Quan
Yanen Leng
En Chang
Yingtao Bai
Yuan Bian
Yi Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496661

541 views

Original Research

Published on 01 Nov 2024

D-mannose reduces oxidative stress, inhibits inflammation, and increases treg cell proportions in mice with ulcerative colitis

in Experimental Pharmacology and Drug Discovery

Yuqing Lu
Yongjian Xiong
Shuangshuang Zhang
Boya Wang
Yuntao Feng
Zhuonan Pu
Kun Wei
Jun Chen
Dapeng Chen
Peng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1454713

403 views

Systematic Review

Published on 01 Nov 2024

Efficacy of different traditional Chinese medicine decoctions in the treatment of ischemic stroke: a network meta-analysis

in Experimental Pharmacology and Drug Discovery

Baicheng Ning
Xiaoting Zhu
Xiaodong Wu
Weiyao Zhu
Runze Wang
Chang Qi
Mingquan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1486458

356 views

Original Research

Accepted on 31 Oct 2024

Preparation and characterization of Pistacia atlantica oleo-gum-resin-loaded electrospun nanofibers and evaluating its wound healing activity in two rat models of skin scar and burn wound

in Experimental Pharmacology and Drug Discovery

Ghobad Mohammadi
Mosayeb Safari
Masoud Karimi
Amin Iranpanah
Mohammad Hosein Farzaei
Sajad Fakhri
Javier Echeverria

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1474981

Original Research

Published on 31 Oct 2024

Isatin improves oligoasthenospermia caused by busulfan by regulating GSH/GPX4 axis to inhibit ferroptosis

in Experimental Pharmacology and Drug Discovery

Chengniu Wang
Weizhen Wang
Jin Dong
Xiaoran Li
Taowen Ye
Fanshuo Zeng
Mingyu Jiang
Jianwu Shi
Xiaorong Wang
Lei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1489956

486 views

Original Research

Published on 31 Oct 2024

Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo

in Experimental Pharmacology and Drug Discovery

Huan Yu
Dan Zhou
Wei Wang
Qingxia Wang
Min Li
Xiaoyun Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1443472

266 views

Original Research

Published on 31 Oct 2024

A computational assay for identifying millet-derived compounds that antagonize the interaction between bisphenols and estrogen-related receptor gamma

in Experimental Pharmacology and Drug Discovery

Rajesh Kumar Pathak
Jun-Mo Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1435254

370 views

Original Research

Published on 31 Oct 2024

Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice

in Experimental Pharmacology and Drug Discovery

Yulian Zou
Chengyan Wang
Huang Li
Meihua Zhong
Jin Lin
Yan Hu
Zhou Chen
Chen-Ling Gan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1500105

580 views

Review

Published on 31 Oct 2024

Pathogenesis of thoracic ossification of the ligamentum flavum

in Experimental Pharmacology and Drug Discovery

Chi Zhang
Yanan Chang
Li Shu
Zhongqiang Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496297

299 views

Review

Published on 30 Oct 2024

Targeting ferroptosis: a novel therapeutic strategy for the treatment of retinal diseases

in Experimental Pharmacology and Drug Discovery

Xiao-Dan Hao
Wen-Hua Xu
Xiaoping Zhang
Junqiang Xue

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1489877

429 views

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Articles

Structure-guided drug repurposing identifies aristospan as a potential inhibitor of β-lactamase: insights from virtual screening and molecular dynamics simulations

Recent advances in extracellular matrix manipulation for kidney organoid research

Berberine ameliorates septic cardiomyopathy through protecting mitochondria and upregulating Notch1 signaling in cardiomyocytes

Yigu decoction regulates plasma miRNA in postmenopausal osteoporosis patients: a randomized controlled trial

Exploring the mechanism of sesamin for the treatment of PM2.5-induced cardiomyocyte damage based on transcriptomics, network pharmacology and experimental verification

Pathologic function and therapeutic potential of extracellular vesicle miRNA in sepsis

Advances of curcumin in nervous system diseases: the effect of regulating oxidative stress and clinical studies

D-mannose reduces oxidative stress, inhibits inflammation, and increases treg cell proportions in mice with ulcerative colitis

Efficacy of different traditional Chinese medicine decoctions in the treatment of ischemic stroke: a network meta-analysis

Preparation and characterization of Pistacia atlantica oleo-gum-resin-loaded electrospun nanofibers and evaluating its wound healing activity in two rat models of skin scar and burn wound

Isatin improves oligoasthenospermia caused by busulfan by regulating GSH/GPX4 axis to inhibit ferroptosis

Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo

A computational assay for identifying millet-derived compounds that antagonize the interaction between bisphenols and estrogen-related receptor gamma

Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice

Pathogenesis of thoracic ossification of the ligamentum flavum

Targeting ferroptosis: a novel therapeutic strategy for the treatment of retinal diseases